Sickle Cell Disease News and Research

Latest Sickle Cell Disease News and Research

New gene editing approach could revolutionize the treatment of blood disorders

In a step forward in the development of genetic medicines, researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have developed a proof-of-concept model for delivering gene editing tools to treat blood disorders, allowing for the modification of diseased blood cells directly within the body.

27 Jul 2023

Rice bioengineers receive NIH grant for sickle cell disease research

Rice University bioengineer Gang Bao and his team have won a 4-year, $2.6 million grant from the National Institutes of Health to address critical questions surrounding the safety and efficacy of using gene editing to treat sickle cell disease.

18 Jul 2023

Study describes the scope and integration of music therapy program within UH medical centers

A new study from University Hospitals (UH) Connor Whole Health describes the scope and integration of their music therapy program within10 UH medical centers.

14 Jul 2023

Sickle cell disease: A global call to action

Reducing the burden of Sickle Cell Disease (SCD) requires substantial financial and political commitment to improving data-collection, diagnosis, treatment and training - doing so will positively impact the lives of millions of patients and families worldwide - says a new Commission published in The Lancet Haematology journal.

12 Jul 2023

Study shows how glutamine can help or hinder cancer-killing activity

Scientists at St. Jude Children's Research Hospital found immune and tumor cells compete over glutamine, a major nutrient in their local environment, with significant implications for anti-cancer activity.

5 Jul 2023

Base editing shows promise for treating sickle cell disease and beta thalassemia

Gene therapy that alters hemoglobin genes may be an answer to curing sickle cell disease (SCD) and beta thalassemia.

3 Jul 2023

New study warns of dangers of gene editing in human embryos

Scientists have discovered that the cells of early human embryos are often unable to repair damage to their DNA.

26 Jun 2023

U.S. patent granted for novel tool designed to reliably diagnose and monitor sickle cell disease

In the United States, sickle cell disease affects about 100,000 people and about 2 million Americans carry this genetic mutation.

22 Jun 2023

New base-edited T-cells proven effective to treat lymphoblastic leukemia

Three young patients with relapsed T-cell leukemia have now been treated with base-edited T-cells, as part of a 'bench-to-bedside' collaboration between UCL and Great Ormond Street Hospital for Children (GOSH).

15 Jun 2023

Study provides a more complete picture of sickle cell disease mortality burden

A new study suggests the number of deaths due to sickle cell disease is 11 times higher than what is indicated from mortality data sources alone. Sickle cell disease is not just underdiagnosed, but it also increases risk of infection and of death from conditions like stroke, heart problems, kidney problems, and pregnancy complications.

13 Jun 2023

Damon Runyon and St. Jude announce a new pediatric-focused fellowship

The Damon Runyon Cancer Research Foundation and St. Jude Children's Research Hospital announced a new pediatric-focused fellowship today.

8 Jun 2023

Electronic health records identified as hidden source of bias impacting clinical trials

Results of clinical trials are only as good as the data upon which they rest. This is especially true in terms of diversity - if most people in a trial are from a certain race or socioeconomic group, then the results may not be broadly applicable.

7 Jun 2023

St. Jude researchers discover NLRP12 as a direct bridge from hemolysis to inflammatory disease

Infections and other diseases can cause red blood cells to rupture, releasing the oxygen-binding molecule hemoglobin, which breaks down into heme.

1 Jun 2023

Genetic change supercharged spread and severity of epizootic H5N1 avian influenza virus

St. Jude Children's Research Hospital scientists discovered how the current epizootic H5N1 avian influenza virus (bird flu) gained new genes and greater virulence as it spread west.

30 May 2023

Scientists study the structure and function of a transporter involved in cancer, immunity

Scientists at St. Jude Children's Research Hospital and the University of Texas Southwestern Medical Center studied the structure and function of a transporter involved in cancer and immunity.

24 May 2023

Targeting the hemoglobin problem in sickle cell disease using a new drug

A class of drugs used for their ability to stop tumor cells from dividing is now under study for their potential to reduce the pain and damage caused by sickle cell disease, investigators report.

11 May 2023

New approach addresses the challenge of directly connecting genetic variants to human traits, health

A major challenge in human genetics is understanding which parts of the genome drive specific traits or contribute to disease risk. This challenge is even greater for genetic variants found in the 98% of the genome that does not encode proteins.

5 May 2023

Neighborhood support may help protect pediatric brain tumor patients from cognitive decline

To gain a clearer understanding of the differences between childhood cancer patients with brain tumors when it comes to the impact of radiation therapy on cognition, scientists at St. Jude Children's Research Hospital studied the effect of their environment.

28 Apr 2023

The Wonder of DNA: Reflections from Dr. Francis Collins on the 20th Anniversary of the Human Genome Project

To highlight how far the field of genetics has come, we spoke with Dr. Francis Collins, the leader of the Human Genome Project about his incredible career in genetics.

25 Apr 2023

Clinical trial may set a new 'gold standard' for the treatment of childhood craniopharyngioma

St. Jude Children's Research Hospital is reporting phase 2 clinical trial results treating the brain tumor craniopharyngioma with proton therapy.

19 Apr 2023

Sickle Cell Disease News and Research

Latest Sickle Cell Disease News and Research

New gene editing approach could revolutionize the treatment of blood disorders

Rice bioengineers receive NIH grant for sickle cell disease research

Study describes the scope and integration of music therapy program within UH medical centers

Sickle cell disease: A global call to action

Study shows how glutamine can help or hinder cancer-killing activity

Base editing shows promise for treating sickle cell disease and beta thalassemia

New study warns of dangers of gene editing in human embryos

U.S. patent granted for novel tool designed to reliably diagnose and monitor sickle cell disease

New base-edited T-cells proven effective to treat lymphoblastic leukemia

Study provides a more complete picture of sickle cell disease mortality burden

Damon Runyon and St. Jude announce a new pediatric-focused fellowship

Electronic health records identified as hidden source of bias impacting clinical trials

St. Jude researchers discover NLRP12 as a direct bridge from hemolysis to inflammatory disease

Genetic change supercharged spread and severity of epizootic H5N1 avian influenza virus

Scientists study the structure and function of a transporter involved in cancer, immunity

Targeting the hemoglobin problem in sickle cell disease using a new drug

New approach addresses the challenge of directly connecting genetic variants to human traits, health

Neighborhood support may help protect pediatric brain tumor patients from cognitive decline

The Wonder of DNA: Reflections from Dr. Francis Collins on the 20th Anniversary of the Human Genome Project

Clinical trial may set a new 'gold standard' for the treatment of childhood craniopharyngioma

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

Sickle Cell Disease News and Research

Latest Sickle Cell Disease News and Research

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

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