T Cell News and Research

Latest T Cell News and Research

Human Argonautes directly cuts messenger RNA

Human Argonautes (hAgo), are key proteins involved in a process known as RNA interference. RNAi, as it is often called, is a mechanism that cells use to regulate gene expression.

7 Jun 2013

Ingenol mebutate drug does not offer added benefit over diclofenac/hyaluronic acid gel

The drug ingenol mebutate (trade name: Picato) has been approved in Germany since November 2012 as a gel for the treatment of certain forms of actinic keratosis in adults. In an early benefit assessment pursuant to the Act on the Reform of the Market for Medicinal Products (AMNOG) the German Institute for Quality and Efficiency in Health Care (IQWiG) examined whether this new drug offers an added benefit over diclofenac/hyaluronic acid gel. Such an added benefit cannot be derived from the dossier, however, as the drug manufacturer did not submit any relevant data: it did not cite any studies that directly compared ingenol mebutate with diclofenac/hyaluronic acid gel, and the method chosen by the manufacturer for an indirect comparison was unsuitable.

7 Jun 2013

Cow antibodies points to new ways for making human medicines

Humans have been raising cows for their meat, hides and milk for millennia. Now it appears that the cow immune system also has something to offer. A new study led by scientists from The Scripps Research Institute (TSRI) focusing on an extraordinary family of cow antibodies points to new ways to make human medicines.

7 Jun 2013

HSV-1 exploits immune system receptor to boost infectivity and cause disease

Researchers at the University of California, San Diego School of Medicine and colleagues report that the herpes simplex virus type-1 (HSV-1), which affects an estimated 50 to 80 percent of all American adults, exploits an immune system receptor to boost its infectivity and ability to cause disease.

7 Jun 2013

Researchers demonstrate how young genes acquire essential functions

Researchers from UConn and other institutions in the U.S. and abroad have shown how a relatively young gene can acquire a new function and become essential to an organism's life.

7 Jun 2013

Researchers define nine molecular hallmarks of aging, debunk myths related to antioxidants

For some species, living twice as long in good health depends on no more than a few genes. When this fact was revealed by studies on worms three decades ago, it ushered in a golden age of ageing studies that has delivered numerous results, but also sown some confusion.

7 Jun 2013

Changes in normal glycan behavior lead to fatal lysosomal disease, say researchers

From the neurons that enable thought to the keratinocytes that make toenails grow-a complex canopy of sugar molecules, commonly known as glycans, envelop every living cell in the human body.

6 Jun 2013

Research reveals how HIV triggers signal to kill infected immune cell

Untreated HIV infection destroys a person's immune system by killing infection-fighting cells, but precisely when and how HIV wreaks this destruction has been a mystery until now. New research by scientists at the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, reveals how HIV triggers a signal telling an infected immune cell to die.

6 Jun 2013

Researchers discover TRF1 gene that is important for nuclear reprogramming

Researchers are still fascinated by the idea of the possibility of reprogramming the cells of any tissue, turning them into cells with the capacity to differentiate into cells of a completely different type- pluripotent cells-and they are still striving to understand how it happens.

6 Jun 2013

BioLineRx starts enrollment in Phase 2 trial of BL-8040 for treatment of AML

BioLineRx, a biopharmaceutical development company, announced today enrollment of the first patient in a Phase 2 trial for BL-8040, for the treatment of acute myeloid leukemia.

6 Jun 2013

Genetic duplication that occurred millions of years ago encouraged evolution of ASF1b gene: Study

How and when evolution generates diversity or gives form to proteins, living beings' functional building blocks, are essential questions that still surround the theory of evolution. In humans, the majority of genes have emerged via genetic duplication, a strategy in which a gene generates two identical copies that can evolve to generate different proteins.

6 Jun 2013

Investigators report possible missing link necessary to prevent osteoporosis

By analyzing biopsy specimens from patients with postmenopausal osteoporosis and primary hyperparathyroidism, investigators have begun to pay increasing attention to "reversal cells," which prepare for bone formation during bone remodeling.

6 Jun 2013

Researchers provide insights into potential therapeutic approaches to Down syndrome

University of Michigan researchers have determined how a gene that is known to be defective in Down syndrome is regulated and how its dysregulation may lead to neurological defects, providing insights into potential therapeutic approaches to an aspect of the syndrome.

6 Jun 2013

BUSM researchers uncover important clues that may expand treatment options for schizophrenia

Researchers at Boston University School of Medicine have uncovered important clues about a biochemical pathway in the brain that may one day expand treatment options for schizophrenia.

6 Jun 2013

New research suggests that surgical anesthesia may also have lasting effects on adult brains

As pediatric specialists become increasingly aware that surgical anesthesia may have lasting effects on the developing brains of young children, new research suggests the threat may also apply to adult brains.

6 Jun 2013

Cells with amplified HER2 gene need to be considered carefully, study says

Biocept, Inc., a privately-held, CLIA certified laboratory testing company focused on detection and analysis of circulating tumor cells and circulating tumor DNA in cancer patients, reported the publication in the journal Cancer Medicine of a paper entitled "Discordance in HER2 gene amplification in circulating and disseminated tumor cells in patients with operable breast cancer" on research performed with collaborators from the University of Texas MD Anderson Cancer Center.

5 Jun 2013

Research demonstrates need for development of new treatments for regeneration of nerve cells

Researchers at the University of Michigan have evidence that a single gene controls both halves of nerve cells, and their research demonstrates the need to consider that design in the development of new treatments for regeneration of nerve cells.

5 Jun 2013

Study suggests modulation of "enhancer-directed RNAs" can alter gene expression in living cells

In a pair of distinct but complementary papers, researchers at the University of California, San Diego School of Medicine and colleagues illuminate the functional importance of a relatively new class of RNA molecules.

5 Jun 2013

New approach in treating multiple sclerosis

In his article, "Pathoetiology of multiple sclerosis: are we barking up the wrong tree?", Peter K. Stys of the Hotchkiss Brain Institute, University of Calgary, argues that while the majority of the medical research community currently approaches MS as an autoimmune disease (much like Lupus and Rheumatoid Arthritis), for which the trigger is the immune system attacking a particular part of the nervous system, the features of the disease are equally well explained by approaching MS as a neurodegenerative disease (such as Parkinson's and Alzheimer's), which is followed by an immune reaction to damage.

5 Jun 2013

Researchers to receive ASTRO Gold Medal for outstanding contributions to the field of radiation oncology

The American Society for Radiation Oncology (ASTRO) will award Amato J. Giaccia, PhD, Radhe Mohan, PhD, FASTRO, and Prabhakar Tripuraneni, MD, FASTRO, with the Society's highest honor—the ASTRO Gold Medal. The 2013 awardees will receive the ASTRO Gold Medal during the Awards Ceremony on Tuesday, September 24, at ASTRO's 55th Annual Meeting, September 22-25, 2013, at the Georgia World Congress Center in Atlanta.

5 Jun 2013

T Cell News and Research

Latest T Cell News and Research

Human Argonautes directly cuts messenger RNA

Ingenol mebutate drug does not offer added benefit over diclofenac/hyaluronic acid gel

Cow antibodies points to new ways for making human medicines

HSV-1 exploits immune system receptor to boost infectivity and cause disease

Researchers demonstrate how young genes acquire essential functions

Researchers define nine molecular hallmarks of aging, debunk myths related to antioxidants

Changes in normal glycan behavior lead to fatal lysosomal disease, say researchers

Research reveals how HIV triggers signal to kill infected immune cell

Researchers discover TRF1 gene that is important for nuclear reprogramming

BioLineRx starts enrollment in Phase 2 trial of BL-8040 for treatment of AML

Genetic duplication that occurred millions of years ago encouraged evolution of ASF1b gene: Study

Investigators report possible missing link necessary to prevent osteoporosis

Researchers provide insights into potential therapeutic approaches to Down syndrome

BUSM researchers uncover important clues that may expand treatment options for schizophrenia

New research suggests that surgical anesthesia may also have lasting effects on adult brains

Cells with amplified HER2 gene need to be considered carefully, study says

Research demonstrates need for development of new treatments for regeneration of nerve cells

Study suggests modulation of "enhancer-directed RNAs" can alter gene expression in living cells

New approach in treating multiple sclerosis

Researchers to receive ASTRO Gold Medal for outstanding contributions to the field of radiation oncology

Immunology eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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