T Cell News and Research

Latest T Cell News and Research

Shortage of TDP-43 protein causes muscle wasting and stunted nerve cells

A shortage of a protein called TDP-43 caused muscle wasting and stunted nerve cells. This finding supports the idea that malfunction of this protein plays a decisive role in ALS and FTD. The study is published in the "Proceedings of the National Academy of Sciences of the USA" (PNAS).

3 Mar 2013

The clock runs out on averting sequestration

Time ticked down to March 1 -- also known as sequestration D-day -- without the White House and lawmakers finding a way to avert the scheduled cuts.

3 Mar 2013

Knockdown or deletion of Jmjd3 gene could improve efficiency of stem cell conversion process

The removal of a genetic roadblock could improve the efficiency of converting adult cells into stem cells by 10 to 30 times, report scientists from The Methodist Hospital Research Institute and two other institutions in the latest issue of Cell.

3 Mar 2013

UNC1215 chemical probe can help investigate L3MBTL3 methyl-lysine reader domain

In an article published as the cover story of the March 2013 issue of Nature Chemical Biology, Lindsey James, PhD, research assistant professor in the lab of Stephen Frye, Fred Eshelman Distinguished Professor in the UNC School of Pharmacy and member of the UNC Lineberger Comprehensive Cancer Center, announced the discovery of a chemical probe that can be used to investigate the L3MBTL3 methyl-lysine reader domain.

3 Mar 2013

Global inhibition of all Notch signals would not be safe after bone marrow transplantation

Bone marrow transplant is a key treatment for patients with leukemia, lymphoma, multiple myeloma and other blood disorders. University of Michigan researchers have discovered that inhibiting a signaling pathway in some of the transplanted cells could prevent the most serious potential complications of the procedure, a conflict between the transplanted cells and the recipient's own tissue called graft-versus-host disease.

2 Mar 2013

Melanoma tumours deliberately create conditions that knock out body's premier immune defence

New research in the Journal of Clinical Investigation reveals that tumours in melanoma patients deliberately create conditions that knock out the body's 'premier' immune defence and instead attract a weaker immune response unable to kill off the tumour's cancerous cells.

2 Mar 2013

Significant link between defective viruses and increased rate of transmission of major disease

Defective viruses, thought for decades to be essentially garbage unrelated to the transmission of normal viruses, now appear able to play an important role in the spread of disease, new research by UCLA life scientists indicates.

2 Mar 2013

Scientists discover enzyme regulation that catalyzes chain elongation in the terpenoid pathway

Max Planck scientists in Jena, Germany, have discovered an unusual regulation of enzymes that catalyze chain elongation in an important secondary metabolism, the terpenoid pathway.

2 Mar 2013

Researchers identify novel signaling pathway responsible for neuroprotective activity of parkin

Researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich identify a novel signal transduction pathway, which activates the parkin gene and prevents stress-induced neuronal cell death.

2 Mar 2013

Synthetic progesterone birth control injections have vulnerability to certain infections: Research

Women who are pregnant or using synthetic progesterone birth control injections have a conspicuous vulnerability to certain infections including malaria, Listeria, HIV, and herpes simplex virus.

2 Mar 2013

Study shows triple-negative breast cancer cells missing key enzyme

A groundbreaking new study led by the University of Kentucky Markey Cancer Center's Dr. Peter Zhou found that triple-negative breast cancer cells are missing a key enzyme that other cancer cells contain - providing insight into potential therapeutic targets to treat the aggressive cancer.

2 Mar 2013

Mercury exposure raises diabetes risk later in life

People with a high level of mercury exposure in young adulthood are at an increased risk for developing diabetes later in life, report researchers.

1 Mar 2013

Kallikrein gene variants modulate OSCC development

Polymorphisms in the kallikrein7 and kallikrein10 genes are associated with the development and progression of oral squamous cell carcinoma, a study in Taiwanese men indicates.

1 Mar 2013

Eye-rubbing may provoke, aggravate keratoconus

Rubbing the eyes leads to an increase in protease activity and levels of protease and inflammatory mediators, a clinical study shows.

1 Mar 2013

First Edition: March 1, 2013

Kaiser Health News staff writer Mary Agnes Carey reports: "David P. Blom is one of thousands of hospital executives across the country who are bracing for a reduction in Medicare payments as part of a series of federal spending cuts that begin Friday. Blom, 58, is president and chief executive officer of OhioHealth, a Columbus, Ohio, based not-for-profit health care system that includes 18 hospitals, 23 health and surgery centers, home-health providers and other facilities."

1 Mar 2013

Researchers elucidate how Fgf8 is controlled by multiple regulatory elements in mammal embryos

During embryo development, genes are dynamically, and very precisely, switched on and off to confer different properties to different cells and build a well-proportioned and healthy animal. Fgf8 is one of the key genes in this process, controlling in particular the growth of the limbs and the formation of the different regions of the brain. Researchers at EMBL have elucidated how Fgf8 in mammal embryos is, itself, controlled by a series of multiple, interdependent regulatory elements.

1 Mar 2013

Pivotal study of olesoxime in Spinal Muscular Atrophy receives positive interim review

Trophos SA, a clinical stage pharmaceutical company developing innovative therapeutics from discovery to clinical validation for under-served medical needs in neurology and cardiology, announced the completion of the interim analysis of the pivotal efficacy study of olesoxime in the rare neurodegenerative condition Spinal Muscular Atrophy (SMA).

1 Mar 2013

Urea cycle disorder patient successfully treated by Promethera(R) HepaStem in Phase I/II trial in France

Promethera Biosciences, a Belgian biotechnology company developing Promethera(R) HepaStem, a cell-based therapy for the treatment of liver-based metabolic diseases including Crigler-Najjar Syndrome and Urea Cycle Disorders, announced that it has successfully treated a patient with liver progenitor cells enrolled in its Phase I/II trial.

1 Mar 2013

New way to identify heterogeneous brain cells by looking at epigenetic variation

Scientists from the Johns Hopkins University School of Medicine in Baltimore, MD have developed a new way to identify heterogeneous brain cells by looking at epigenetic variation (the heritable alterations in gene expression caused by mechanisms other than changes in DNA sequence).

1 Mar 2013

Not all acne bacteria trigger pimples: Study

The bacteria that cause acne live on everyone's skin, yet one in five people is lucky enough to develop only an occasional pimple over a lifetime.

1 Mar 2013

T Cell News and Research

Latest T Cell News and Research

Shortage of TDP-43 protein causes muscle wasting and stunted nerve cells

The clock runs out on averting sequestration

Knockdown or deletion of Jmjd3 gene could improve efficiency of stem cell conversion process

UNC1215 chemical probe can help investigate L3MBTL3 methyl-lysine reader domain

Global inhibition of all Notch signals would not be safe after bone marrow transplantation

Melanoma tumours deliberately create conditions that knock out body's premier immune defence

Significant link between defective viruses and increased rate of transmission of major disease

Scientists discover enzyme regulation that catalyzes chain elongation in the terpenoid pathway

Researchers identify novel signaling pathway responsible for neuroprotective activity of parkin

Synthetic progesterone birth control injections have vulnerability to certain infections: Research

Study shows triple-negative breast cancer cells missing key enzyme

Mercury exposure raises diabetes risk later in life

Kallikrein gene variants modulate OSCC development

Eye-rubbing may provoke, aggravate keratoconus

First Edition: March 1, 2013

Researchers elucidate how Fgf8 is controlled by multiple regulatory elements in mammal embryos

Pivotal study of olesoxime in Spinal Muscular Atrophy receives positive interim review

Urea cycle disorder patient successfully treated by Promethera(R) HepaStem in Phase I/II trial in France

New way to identify heterogeneous brain cells by looking at epigenetic variation

Not all acne bacteria trigger pimples: Study

Immunology eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

Newsletters you may be interested in