T Cell News and Research

Latest T Cell News and Research

Leukemia & Lymphoma Society awards SCOR program grant to Walter and Eliza Hall Institute team

Research into the natural process of cell death, its role in the development of blood cancers and harnessing cell death to improve cancer therapies has seen a Walter and Eliza Hall Institute research team from Melbourne, Australia, awarded a grant of more than $6 million by the US-based Leukemia & Lymphoma Society.

7 Sep 2012

American troops with noise-induced hearing loss, tinnitus may benefit from novel strategies

Antioxidants, dietary supplements and high-tech brain imaging are among some of the novel strategies that may help detect, treat and even prevent noise-induced hearing loss and tinnitus among American troops, according to researchers at Henry Ford Hospital.

7 Sep 2012

Drug discovery solutions from SPT Labtech to be demonstrated at MipTech

SPT Labtech will be offering delegates at MipTec 2012 (24th-27th September, Basel, Switzerland) the opportunity to experience their innovative automated solutions for effortless drug discovery first-hand.

From SPT Labtech 7 Sep 2012

Children and young patients with chronic HBV infection do have a protective immune response

Scientists from A*STAR's Singapore Institute for Clinical Sciences (SICS), together with clinical collaborators from London , discovered for the first time that children and young patients with chronic Hepatitis B Virus infection (HBV carriers) do have a protective immune response, contrary to current belief, and hence can be more suitable treatment candidates than previously considered.

7 Sep 2012

Mammalian target of rapamycin inhibitors can prevent radiation-induced tissue damage

Radiation therapy is one of the most widely used cancer treatments, but it often damages normal tissue and can lead to debilitating conditions. A class of drugs known as mammalian target of rapamycin (mTOR) inhibitors can prevent radiation-induced tissue damage in mice by protecting normal stem cells that are crucial for tissue repair, according to a preclinical study published by Cell Press in the September issue of the journal Cell Stem Cell.

7 Sep 2012

Germline BAP1 mutations associated with novel cancer syndrome

University of Hawai'i Cancer Center researchers have discovered germline BAP1 mutations are associated with a novel cancer syndrome characterized by malignant mesothelioma, uveal melanoma, cutaneous melanoma and atypical melanocytic tumors. Germline mutations are hereditary gene defects that are present in every cell.

7 Sep 2012

Hispanics/Latinos with non-small cell lung cancer have higher overall survival rates

Analysis of non-small cell lung cancer (NSCLC) patient records in the California Cancer Registry (CCR) database during the 20-year period of 1988-2008 indicates that Hispanics/Latinos with NSCLC have a higher overall survival compared to non-Hispanic white patients, according to research presented at the 2012 Chicago Multidisciplinary Symposium in Thoracic Oncology.

7 Sep 2012

Adding bavituximab to docetaxel doubles overall survival in late-stage NS-NSCLC patients

Adding the monoclonal antibody bavituximab to docetaxel chemotherapy doubles overall response rate and improves progression-free survival and overall survival in late-stage non-squamous, non-small cell lung cancer (NS-NSCLC) patients who have already received one prior chemotherapy regimen, according to research presented at the 2012 Chicago Multidisciplinary Symposium in Thoracic Oncology.

7 Sep 2012

Married patients with locally advanced lung cancer likely to survive longer after treatment

Married patients with locally advanced lung cancer are likely to survive longer after treatment than patients who are single, according to a study by researchers at the University of Maryland Marlene and Stewart Greenebaum Cancer Center in Baltimore.

7 Sep 2012

PCI after lung cancer treatment reduces risk of brain metastases in stage III NSCLC patients

Stage III non-small cell lung cancer (NSCLC) patients treated with surgery and/or radiation therapy have a significantly reduced risk of developing brain metastases if they also receive prophylactic cranial irradiation (PCI); however, this study did not show an improvement in overall survival with PCI, according to research presented at the 2012 Chicago Multidisciplinary Symposium in Thoracic Oncology.

7 Sep 2012

Study investigates effects of acidity on breast and pancreatic cancer cell lines

Researchers at Moffitt Cancer Center and colleagues at the University of South Florida and Wayne State University have discovered that tumor cell survival relies on adaptation to acidic conditions in the tumor microenvironment.

7 Sep 2012

Crizotinib effective in shrinking tumors in patients with ALK positive non-small cell lung cancer

Crizotinib is effective in shrinking tumors in patients with anaplastic lymphoma receptor tyrosine kinase (ALK) positive non-small cell lung cancer, a cancer commonly found in people who never smoked, and should be the standard of care for advanced stages of this disease, according to research presented at the 2012 Chicago Multidisciplinary Symposium in Thoracic Oncology.

7 Sep 2012

Race, marital status can impact survival rates of patients with Stage III non-small cell lung cancer

A study of survival data for Stage III, non-small cell lung cancer (NSCLC) patients at the University of Maryland's Greenebaum Cancer Center in Baltimore indicates that marital status and race can significantly impact patient survival rates, according to research presented at the 2012 Chicago Multidisciplinary Symposium in Thoracic Oncology.

7 Sep 2012

OncoMed announces data from demcizumab preclinical study on pancreatic cancer

OncoMed Pharmaceuticals, Inc., a clinical-stage company developing novel therapeutics that target cancer, today announced the online publication in Clinical Cancer Research of preclinical data demonstrating the potent anti-cancer activity of anti-DLL4 (demcizumab) in patient-derived pancreatic tumor models.

7 Sep 2012

DNA synthesis methods: an interview with Clemens Richert

Automated DNA synthesis has been around for almost three decades. The key difference between the established methodology for making oligodeoxynucleotides (short stretches of single-stranded DNA) and our method is the template strand.

7 Sep 2012

RSV virus selectively kills cancer cells

RSV, a virus that causes respiratory infections in infants and young children, selectively kills cancer cells while leaving healthy cells alone, researchers from the School of Medicine at The University of Texas Health Science Center San Antonio said.

7 Sep 2012

GENCODE Consortium uncovers staggering array of genes in human genome

The GENCODE Consortium expects the human genome has twice as many genes than previously thought, many of which might have a role in cellular control and could be important in human disease. This remarkable discovery comes from the GENCODE Consortium, which has done a painstaking and skilled review of available data on gene activity.

7 Sep 2012

Book examines highly complex structures of synaptic regions

Synapses are bulbous structures where two neurons communicate. Neurotransmitter molecules released from the presynaptic terminal of one neuron diffuse to the postsynaptic terminal on the other, binding to receptors that lead to propagation or modulation of the signal.

7 Sep 2012

Absence of Puma and Bim protein leads to autoimmune diseases

Researchers at the Walter and Eliza Hall Institute have discovered that a pair of molecules work together to kill so-called 'self-reactive' immune cells that are programmed to attack the body's own organs.

7 Sep 2012

Study finds PARP1 and EZH2 as potential therapeutic targets for small cell lung cancer

Newly discovered molecular differences between small cell lung cancer and nonsmall cell lung cancer have revealed PARP1 and EZH2 as potential therapeutic targets for patients with small cell lung cancer, according to the results of a study published in Cancer Discovery, a journal of the American Association for Cancer Research.

7 Sep 2012

T Cell News and Research

Latest T Cell News and Research

Leukemia & Lymphoma Society awards SCOR program grant to Walter and Eliza Hall Institute team

American troops with noise-induced hearing loss, tinnitus may benefit from novel strategies

Drug discovery solutions from SPT Labtech to be demonstrated at MipTech

Children and young patients with chronic HBV infection do have a protective immune response

Mammalian target of rapamycin inhibitors can prevent radiation-induced tissue damage

Germline BAP1 mutations associated with novel cancer syndrome

Hispanics/Latinos with non-small cell lung cancer have higher overall survival rates

Adding bavituximab to docetaxel doubles overall survival in late-stage NS-NSCLC patients

Married patients with locally advanced lung cancer likely to survive longer after treatment

PCI after lung cancer treatment reduces risk of brain metastases in stage III NSCLC patients

Study investigates effects of acidity on breast and pancreatic cancer cell lines

Crizotinib effective in shrinking tumors in patients with ALK positive non-small cell lung cancer

Race, marital status can impact survival rates of patients with Stage III non-small cell lung cancer

OncoMed announces data from demcizumab preclinical study on pancreatic cancer

DNA synthesis methods: an interview with Clemens Richert

RSV virus selectively kills cancer cells

GENCODE Consortium uncovers staggering array of genes in human genome

Book examines highly complex structures of synaptic regions

Absence of Puma and Bim protein leads to autoimmune diseases

Study finds PARP1 and EZH2 as potential therapeutic targets for small cell lung cancer

Immunology eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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