T Cell News and Research

Latest T Cell News and Research

Tissues in SIV-infected monkeys can ramp up production of Tregs

Tissue in monkeys infected with a close relative of HIV can ramp up production of a type of T cell that actually weakens the body's attack against the invading virus. The discovery, in lymph nodes draining the intestinal tract, could help explain how the HIV virus evades the body's immune defenses.

15 Feb 2012

U-M's first human embryonic stem cell line to be placed on the U.S.NIH registry

The University of Michigan's first human embryonic stem cell line will be placed on the U.S. National Institutes of Health's registry, making the cells available for federally-funded research. It is the first of the stem cell lines derived at the University of Michigan to be placed on the registry.

15 Feb 2012

Curcumin prolongs life and enhances activity of fruit flies with AD

Curcumin, a substance extracted from turmeric, prolongs life and enhances activity of fruit flies with a nervous disorder similar to Alzheimers. The study conducted at Link-ping University, indicates that it is the initial stages of fibril formation and fragments of the amyloid fibrils that are most toxic to neurons.

15 Feb 2012

New vaccine can prevent bacterial infection of orthopaedic implants

Methicillin resistant staph aureus (MRSA) infections are resistant to antibiotics and can cause a myriad of problems -- bone erosion, or osteomyelitis, which shorten the effective life of an implant and greatly hinder replacement of that implant. MRSA can result in prolonged disability, amputation and even death.

15 Feb 2012

Study shows how malaria parasite changes into banana form before sexual reproduction

New research from the University of Melbourne shows how the malaria parasite (Plasmodium falciparum) changes into a banana shape before sexual reproduction, a finding that could provide targets for vaccine or drug development and may explain how the parasite evades the human immune system.

14 Feb 2012

Scientists identify and describe molecular mechanism behind holoprosencephaly

Researchers of the Max Delbr-ck Center for Molecular Medicine (MDC) Berlin-Buch have now identified and described a molecular mechanism underlying the most common malformation of the brain in humans. In holoprosencephaly (HPE), the forebrain (prosencephalon) is only incompletely formed.

14 Feb 2012

Aspirin-like drugs help prevent spread of tumors in the body

Australian scientists have made a breakthrough which could help in the fight against cancer. The team from Peter MacCallum Cancer Centre in Melbourne has found a link between non-steroidal anti-inflammatory drugs (NSAIDs), such as aspirin, and the ability of tumours to spread in the body. They say that doctors have been aware of the benefits of NSAIDs for many years, but did not fully understand the biological processes involved.

14 Feb 2012

Gene sequencing could identify genetic variants of lung cancer and colorectal cancer

Foundation Medicine Inc., a molecular information company that brings comprehensive cancer gene analysis to routine clinical care, and Dana-Farber Cancer Institute have come up with the results from their collaborative next-generation sequencing (NGS) study to assay cancer-relevant genes in 24 non-small cell lung cancer (NSCLC) and 40 colorectal cancer (CRC) cases.

14 Feb 2012

Epigenetic mechanisms maintain tolerance in T cells specific for self antigens

At the most basic level, the immune system must distinguish self from non-self, that is, it must discriminate between the molecular signatures of invading pathogens (non-self antigens) and cellular constituents that usually pose no risk to health (self-antigens).

14 Feb 2012

National Library of Medicine acquires papers of sickle cell disease expert

The National Library of Medicine of the National Institutes of Health (NIH), the world's largest medical library, announced recently the acquisition of the papers of Charles F. Whitten, M.D., distinguished professor of pediatrics and associate dean of medicine emeritus at Wayne State University. Whitten passed away in 2008.

14 Feb 2012

New light on treatment targets for potentially life-threatening cardiac arrhythmia conditions

That flutter in your heart may have more to do with the movement of sodium ions than the glance of a certain someone across a crowded room.

14 Feb 2012

'Targeted' drugs may be effective against lung and colorectal tumors driven by novel gene abnormalities

Novel gene abnormalities discovered in a subpopulation of lung and colorectal tumors could potentially identify patients with a good chance of responding to highly specific "targeted" drugs already in use for treating other cancers, scientists report.

14 Feb 2012

Radiation treatment transforms breast cancer stem cells into new iBCSCs

Breast cancer stem cells are thought to be the sole source of tumor recurrence and are known to be resistant to radiation therapy and don't respond well to chemotherapy.

14 Feb 2012

Scientists create fungi with additional foreign genes to produce chemicals for drugs

Usually, mould fungi are nothing to cheer about - but now they can be used as "chemical factories". Scientists at the Vienna University of Technology have succeeded in introducing bacterial genes into the fungus Trichoderma, so that the fungus can now produce important chemicals for the pharmaceutical industry. The raw material used by the fungus is abundant - it is chitin, which makes up the shells of crustaceans.

14 Feb 2012

Tips to reduce car accident risk among teens

Teenage drivers are four times more likely than an adult driver to get into a car accident according to the Centers for Disease Control. The elevated risk comes in wake of a young driver's inexperience coupled with the natural tendency to want to test or break the rules. As a car accident lawyer in San Diego, there are many cases that come across my desk involving young, inexperienced drivers.

14 Feb 2012

Fresh insights into cell division could help scientists develop cancer drugs

Fresh insights into how our cells multiply could help scientists develop drugs to treat cancer. Researchers have gained better understanding of the workings of two key proteins that control cell division. This process must be carried out accurately to keep cells healthy, and when it goes out of control, it can lead to cancer.

14 Feb 2012

New potential therapy for Huntington disease

Medical researchers at the University of Alberta have discovered a promising new therapy for Huntington disease that restores lost motor skills and may delay or stop the progression of the disease based on lab model tests, says the lead researcher.

14 Feb 2012

Radiation induces testicular cancer in male fetuses

Male fetuses of mothers that are exposed to radiation during early pregnancy may have an increased chance of developing testicular cancer, according to a study in mice at The University of Texas MD Anderson Cancer Center.

14 Feb 2012

Scientists create new mouse model for medulloblastoma

Scientists at Sanford-Burnham Medical Research Institute (Sanford-Burnham) developed a new mouse model for studying a devastating childhood brain cancer called medulloblastoma.

14 Feb 2012

Two studies demonstrate preliminary success of CyBorD in AL amyloidosis

Two studies published today in Blood, the Journal of the American Society of Hematology (ASH), demonstrate preliminary success of an effective multiple myeloma (MM) regimen in patients with AL amyloidosis, a rare and devastating blood disease that results in deposition of damaging abnormal protein in critical organs of the body, including the kidneys, heart, liver, and intestines, and shares some characteristics with MM.

14 Feb 2012