T Cell News and Research

Latest T Cell News and Research

RBC storage duration not associated with transfusion-related pulmonary complications

There is no difference in early measures of pulmonary function, immunologic status or coagulation status after fresh versus standard issue single-unit red blood cell (RBC) transfusion, according to a new study from the Mayo Clinic.

21 Jan 2012

Texas abortion issue back in court today

A Federal judge in Austin holds another hearing on Texas law requiring women seeking an abortion to have a sonogram. Also, NPR looks at the growing number of restrictions across the country.

21 Jan 2012

NCI-funded project aims to shed new light on implications for bone metastasis in prostate cancer

Prostate cancer is the most frequent and second deadliest cancer men face. A team of Wayne State University researchers recently received $363,660 from the National Cancer Institute of the National Institutes of Health for the project - "Bone-induced c-kit in prostate cancer cells: implications for bone metastasis" - that aims to shed new light on implications for bone metastasis in prostate cancer.

21 Jan 2012

Exercise fails to improve glucose metabolism in autophagy-deficient mice

The health benefits of exercise on blood sugar metabolism may come from the body's ability to devour itself, UT Southwestern Medical Center researchers report in the journal Nature.

21 Jan 2012

Combination of gefitinib and miRNA-inhibitor might effectively treat NSCLC

New research published in Nature Medicine indicates that targeted drugs such as gefitinib might more effectively treat non-small cell lung cancer if they could be combined with agents that block certain microRNAs.

20 Jan 2012

Novel imaging platform reveals new details on aggressive cancer development

When cancers become aggressive and spread they are the most deadly. Unfortunately, little is known about how to stop this development. A new imaging platform developed by Lawson Health Research Institute's Drs. Ann Chambers and John Lewis is providing insight into just that - the exact moment when cancer cells turn deadly.

20 Jan 2012

Cedars-Sinai's annual Brainworks program to take place on Feb. 13

Taking turns gazing into a surgical microscope, 130 seventh- and eighth-graders from Los Angeles area schools will see a phantom skull and perform virtual surgery - and many could catch a glimpse of the future.

20 Jan 2012

WSU professors receive NSF grant to develop math model of liver metabolism

Predicting problems in one of the body's most complex organs soon may become easier because of work being done by Wayne State University researchers.

20 Jan 2012

Making Cancer History seminar to take place on Feb. 11

Cancer experts from The University of Texas MD Anderson Cancer Center return to West Palm Beach Feb. 11 for the institution's annual Making Cancer History seminar. The event, in the Cohen Pavilion of the Raymond F. Kravis Center for the Performing Arts, 701 Okeechobee Blvd., begins at 8:30 a.m. with a breakfast buffet.

20 Jan 2012

Scientists discover unexpected way in which a neutrophil prepares for battle

UCSF scientists have discovered the unexpected way in which a key cell of the immune system prepares for battle. The finding, they said, offers insight into the processes that take place within these cells and could lead to strategies for treating conditions from spinal cord injury to cancer.

20 Jan 2012

Inflammation enhances pancreatic cancer cell progression

Ben Stanger, MD, PhD, assistant professor of Medicine in the Division of Gastroenterology at the Perelman School of Medicine, University of Pennsylvania, and Andrew Rhim, MD, a Gastroenterology Fellow in the Stanger lab, discovered that pancreatic cancer cells in an animal model begin to spread before clinically obvious tumor tissue is detected.

20 Jan 2012

EMA CHMP may issue an opinion on CTI's Pixuvri MAA in mid-Feb.

Cell Therapeutics, Inc. ("CTI") announced today that, following discussions with the European Medicines Agency's ("EMA") Committee for Medicinal Products for Human Use ("CHMP"), the CHMP may issue an opinion on CTI's Marketing Authorization Application ("MAA") for Pixuvri in mid-February.

20 Jan 2012

MSC-mediated RNAi transfer holds promise for Huntington's disease

A team of researchers at the UC Davis Institute for Regenerative Cures has developed a technique for using stem cells to deliver therapy that specifically targets the genetic abnormality found in Huntington's disease, a hereditary brain disorder that causes progressive uncontrolled movements, dementia and death.

20 Jan 2012

Defect in neuronal RNA splicing process may contribute to neurological disease

A Jackson Laboratory research team led by Professor and Howard Hughes Medical Investigator Susan Ackerman, Ph.D., has discovered a defect in the RNA splicing process in neurons that may contribute to neurological disease.

20 Jan 2012

Distal-less gene plays a critical role in development of fruit fly olfactory system

Fruit flies don't have noses, but a huge part of their brains is dedicated to processing smells. Flies probably rely on the sense of smell more than any other sense for essential activities such as finding mates and avoiding danger. UW-Madison researchers have discovered that a gene called distal-less is critical to the fly's ability to receive, process and respond to smells.

20 Jan 2012

Inherited mutation links exploding chromosomes to cancer

An inherited mutation in a gene known as the guardian of the genome is likely the link between exploding chromosomes and some particularly aggressive types of cancer, scientists at the European Molecular Biology Laboratory (EMBL), the German Cancer Research Centre (DKFZ) and the University Hospital, all in Heidelberg, Germany, have discovered.

20 Jan 2012

Study investigates immune response in cancer

In a study investigating immune response in cancer, researchers from Moffitt Cancer Center in Tampa, Fla., and the University of South Florida have found that interaction between the immune system's antigen-specific CD4 T cells and myeloid-derived suppressor cells (MDSC) - cells that play a major role in cancer-related immune suppression - dramatically change the nature of MDSC-mediated suppression. By contrast, the same effect was not observed when MDSCs interacted with the immune system's CD8 T cells.

20 Jan 2012

Researchers reveal role of micronuclei in cancer process

They are the Robinson Crusoes of the intracellular world -- lone chromosomes, whole and hardy, stranded outside the nucleus where their fellow chromosomes reside. Such castaways, each confined to its own "micronucleus," are often found in cancer cells, but scientists haven't known what role, if any, they play in the cancer process.

20 Jan 2012

New federal drug label recommendations for CKD patients

The U.S. Food and Drug Administration (FDA) recently recommended that clinicians be more conservative when they prescribe chronic kidney disease (CKD) patients with drugs that treat red blood cell deficiencies. But the drug label's recommendations fall short, according to two commentaries appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology.

20 Jan 2012

Study explains gender-related incidence of liver cancer

Men are four times more likely to develop liver cancer compared to women, a difference attributed to the sex hormones androgen and estrogen. Although this gender difference has been known for a long time, the molecular mechanisms by which estrogens prevent -- and androgens promote -- liver cancer remain unclear.

20 Jan 2012