T Cell News and Research

Latest T Cell News and Research

Quanticel, Celgene and Versant enter collaboration to discover and develop first-in-class cancer drugs

Privately held biotechnology company Quanticel Pharmaceuticals Inc. and Celgene Corporation, together with Versant Ventures, today announced they have entered into an exclusive, strategic collaboration to discover and develop first-in-class cancer drugs.

4 Nov 2011

New technologies could aid in malignant melanoma diagnosis and therapy

Because the incidence of malignant melanoma is rising faster than any other cancer in the U.S., researchers at Moffitt Cancer Center in Tampa, Fla., and colleagues at Tampa-based Intezyne Technologies, Inc., Western Carolina University and the University of Arizona are working overtime to develop new technologies to aid in both malignant melanoma diagnosis and therapy.

4 Nov 2011

Cerebellum contributes to creation of cognitive map in the hippocampus

The cerebellum is far more intensively involved in helping us navigate than previously thought. To move and learn effectively in spatial environments our brain, and particularly our hippocampus, creates a "cognitive" map of the environment. The cerebellum contributes to the creation of this map through altering the chemical communication between its neurones. If this ability is inactivated, the brain is no longer able to to create an effective spatial representation and thus navigation in an environment becomes impaired.

4 Nov 2011

Early diagnosis of large intestine cancer could be feasible in the long term

Itxaro Perez, a biochemist at the University of the Basque Country (UPV/EHU), has contributed in such a way that, in the long term, the early diagnosis of cancer of the large intestine could be feasible.

4 Nov 2011

Inserm researchers successfully rejuvenate cells from elderly donors

Inserm's AVENIR "Genomic plasticity and aging" team, directed by Jean-Marc Lemaitre, Inserm researcher at the Functional Genomics Institute, has recently succeeded in rejuvenating cells from elderly donors.

4 Nov 2011

Important to keep obstacles to malaria control in mind as research moves forward

In a post in the Center for Strategic & International Studies' "Smart Global Health" blog, Julia Nagel, web and social media assistant at the Global Health Policy Center, examines "the obstacles that global malaria control efforts face," writing that "eradicating malaria is complex and difficult" because "there are four species of human malaria" that "respond differently to medicines, exhibit drug resistance in different ways, and most importantly, make finding a fool-proof vaccine against all malaria nearly impossible."

4 Nov 2011

Einstein scientists receive two NCI grants to study cancer metastasis

The National Cancer Institute (NCI) has awarded Albert Einstein College of Medicine of Yeshiva University two grants totaling $8 million to study the microenvironments that drive the spread of cancer from the primary tumor to other parts of the body in the process known as metastasis.

4 Nov 2011

Scientists discover alternative mechanism for extension of telomeres

Scientists of the German Cancer Research Center have discovered an alternative mechanism for the extension of the telomere repeat sequence by DNA repair enzymes.

4 Nov 2011

Penn research group receives NCI grant to establish BETRNet

A research group at the Perelman School of Medicine of the University of Pennsylvania, led by John Lynch, MD, PhD, assistant professor of Medicine in the Division of Gastroenterology, has received a National Cancer Institute (NCI) grant to establish a Barrett's esophagus translational research network (BETRNet) with Columbia University and the Mayo Clinic.

4 Nov 2011

Slowing aging by cleaning away old cells: Study

Researchers have found a novel way of reversing the aging process. They found that a special category of cells, known as senescent cells, are bad actors that promote the aging of the tissues. Cleansing the body of the cells, they hope, could postpone many of the diseases of aging. This could pave the way for drugs that would keep human tissues healthier longer, but it is unclear until further testing is done whether such drugs could eventually help people live longer.

3 Nov 2011

Cancer cells maintain rapid proliferation due to PK-M2 enzyme

Cancer cells maintain their life-style of extremely rapid growth and proliferation thanks to an enzyme called PK-M2 (pyruvate kinase M2) that alters the cells' ability to metabolize glucose - a phenomenon known as the Warburg effect.

3 Nov 2011

Gene therapy and stem cell transplantation successfully reverse hemophilia A

For the first time, researchers have combined gene therapy and stem cell transplantation to successfully reverse the severe, crippling bleeding disorder hemophilia A in large animals, opening the door to the development of new therapies for human patients.

3 Nov 2011

Allos third quarter net loss decreases to $11.2 million

Allos Therapeutics, Inc. today reported financial results for the three months ended September 30, 2011.

3 Nov 2011

ARIAD reports net income of $13.9 million for third quarter 2011

ARIAD Pharmaceuticals, Inc. today reported financial results for the third quarter of 2011 and provided an update on its corporate developments.

3 Nov 2011

Breakdown of unsaturated fats can induce complications in obese patients with acute pancreatitis

The toxic byproducts produced by the breakdown of unsaturated fats lead to a higher likelihood of severe inflammation, cell death and multi-system organ failure among acute pancreatitis patients who are obese, say researchers at the University of Pittsburgh School of Medicine.

3 Nov 2011

New study in fruit flies offers clues to delay human aging

One of the few reliable ways to extend an organism's lifespan, be it a fruit fly or a mouse, is to restrict calorie intake. Now, a new study in fruit flies is helping to explain why such minimal diets are linked to longevity and offering clues to the effects of aging on stem cell behavior.

3 Nov 2011

Study reveals what causes lysosome to overflow in Batten disease

Waste management is a big issue anywhere, but at the cellular level it can be a matter of life and death. A Weizmann Institute study, published in the Journal of Cell Biology, has revealed what causes a molecular waste container in the cell to overflow in Batten disease, a rare but fatal neurodegenerative disorder that begins in childhood.

3 Nov 2011

Increasing TR2/TR4 expression can lead to higher fetal hemoglobin levels in sickle cell patients

A University of Michigan Health System laboratory study reveals a key trigger for producing normal red blood cells that could lead to a new treatment for those with sickle cell disease.

3 Nov 2011

BUSM researcher receives two NIH grants to study scleroderma

Boston University School of Medicine (BUSM) researcher Robert Lafyatis, MD, recently was awarded two grants from the National Institutes of Health's (NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases.

3 Nov 2011

Scientists discover how to starve prostate cancer cells

Each year about 3300 Australian men die of prostate cancer. It's Australia's second worst cancer killer for men, matching the impact of breast cancer on women. Current therapies for prostate cancer include surgical removal of the prostate, radiation, freezing the tumour or cutting off the supply of the hormone testosterone-but there are often side-effects including incontinence and impotence.

3 Nov 2011