Typhoid Fever

Typhoid fever is a life-threatening illness caused by the bacterium Salmonella Typhi. Typhoid fever is still common in the developing world, where it affects about 21.5 million persons each year.

What is Typhoid?

Typhoid fever is an infection caused by a strain of bacteria called Salmonella typhii, which is related to the bacteria that causes salmonella food poisoning. The infection can affect the whole body and damage multiple organs. Unless treated, this infection can have life threatening consequences.

Typhoid Symptoms

Typhoid Diagnosis

Typhoid Treatment

Typhoid Prevention

Typhoid Fever History

Latest Typhoid Fever News and Research

Advancing the development of vaccines through recombinant technology

In this interview, News-Medical talks to Dr. Amy Sheng, the head of CRO at Sino Biological, about current developments in the field of vaccine development through recombinant techniques.

From Sino Biological Inc. 4 May 2023

Tissue-resident memory cells are key to immunity to Salmonella in mice

Salmonella infections cause about a million deaths a year worldwide, and there is an urgent need for better vaccines for both typhoid fever and non-typhoidal Salmonella disease.

18 Apr 2023

Study demonstrates safety and efficacy of a three-dose whole-parasite vaccine against malaria

A three-dose regimen of a whole-parasite vaccine against malaria – called Plasmodium falciparum sporozoite (PfSPZ) vaccine – demonstrated safety and efficacy when tested in adults living in Burkina Faso, West Africa, which has endemic malaria.

4 Jan 2023

Antibiotic-resistant strains of typhoid bacteria continue to spread out of South Asia

Antibiotic-resistant strains of Salmonella Typhi, the typhoid bacteria, have spread from South Asia to other countries nearly 200 times since 1990, new research suggests.

29 Jun 2022

Drug-resistant typhoid needs to be treated as a global problem

The bacteria that causes typhoid fever is becoming increasingly resistant to common antibiotics used to treat the disease, with resistant strains spreading to hundreds of countries in the past three decades, new analysis shows.

29 Jun 2022

Bacteria causing typhoid fever are highly developing antibiotic resistance

Bacteria causing Typhoid fever are becoming increasingly resistant to some of the most important antibiotics for human health, according to a study published in The Lancet Microbe journal. The largest genome analysis of Salmonella enterica serovar Typhi (S. Typhi) also reveals that resistant strains - almost all originating in South Asia - have spread to other countries nearly 200 times since 1990.

22 Jun 2022

World Immunization Week 2022: Striving for a Long Life for All with the International Vaccine Institute

As part of World Immunization Week 2022, News Medical speaks to the International Vaccine Institute about their fight against vaccine inequity, as well as what a “Long Life for All” means to them.

25 Apr 2022

Study assesses how vaccination against typhoid fever could help avert antimicrobial resistance

Researchers from Yale University, University of Basel, University of Antwerp, CDDEP and other institutions recently published 'Estimating the effect of vaccination on antimicrobial-resistant typhoid fever in 73 countries supported by Gavi: a mathematical modeling study' in The Lancet Infectious Diseases.

4 Feb 2022

COVID-19 first wave increased the sale of antibiotic formulations in India

The first wave of COVID-19 in 2020 in India saw a substantial increase in the sale of antibiotic formulations used in adults and adolescents, especially azithromycin, says a study.

19 Jul 2021

Role of traditional medicine against SARS-CoV-2

A group of researchers at Kannur University reviewed selected papers and in silico work on potential drug leads that could be used to manage COVID-19.

13 Jun 2021

Covid strikes clergy as they comfort pandemic’s sick and dying

The Rev. Jose Luis Garayoa survived typhoid fever, malaria, a kidnapping and the Ebola crisis as a missionary in Sierra Leone, only to die of Covid-19 after tending to the people of his Texas church who were sick from the virus and the grieving family members of those who died.

23 Feb 2021

Antimicrobial resistance to critical drugs spirals in low- and middle-income countries

As antibiotic use grows in lower-income countries so does antibiotic resistance, says report.

20 Feb 2021

Vi-DT typhoid conjugate vaccine met primary endpoints in phase III study

Vi-DT typhoid conjugate vaccine, developed jointly by the International Vaccine Institute (IVI) and SK bioscience, has met the primary endpoints in a phase III study in Nepal.

17 Dec 2020

MARA project aims to use new DNA based nanotechnology to fight bacteria

Antibiotics are used to prevent and treat bacterial infections. They have played a major role in combating infectious diseases such as tuberculosis, pneumonia, typhoid fever, and meningitis in 20th century.

27 Nov 2020

Multiple, intertwined cell death systems to prevent the spread of 'intracellular' bacteria

Melbourne researchers have revealed the multiple, intertwined cell death systems that prevent the spread of the 'intracellular' bacterium Salmonella, an important cause of typhoid fever which kills more than 100,000 people annually.

30 Jul 2020

Lymphopenia may hint a higher risk of future illness, death

Lymphopenia, which indicates lower levels of lymphocytes in the blood, has been tied to a higher risk of future illness and death, a new study found.

13 Jan 2020

UMSOM research shows even milder cases of diarrheal diseases can lead to child mortality

Diarrheal diseases are a leading cause of death for young children, accounting for nine percent of all deaths worldwide in children under five years of age, with most occurring in children under two years of age.

9 Jan 2020

UMSOM researchers to test the safety, tolerability of prototype Shigella-ETEC vaccine

Each year, millions of people contract serious diarrheal illnesses typically from contaminated food and water. Among the biggest causes of diarrheal diseases are the bacteria Shigella and enterotoxigenic Escherichia coli, and researchers at the University of Maryland School of Medicine are testing a vaccine designed to offer protection against these serious pathogens.

10 Dec 2019

UMSOM receives landmark contract from NIAID for influenza research

Kathleen Neuzil, MD, MPH, Professor of Medicine and Pediatrics and Director of the Center for Vaccine Development and Global Health at the University of Maryland School of Medicine and Dean E. Albert Reece, MD, PhD, MBA, announced that CVD has been awarded a contract from the National Institute of Allergy and Infectious Diseases, with total funding up to more than $200 million over seven years if all contract options are exercised.

20 Sep 2019

Researchers study typhoid genomes of travelers from different parts of the world

Salmonella enterica serovar Typhi causes more than 20 million cases of typhoid fever each year, and disproportionately infects children in low and middle income countries.

From PLOS ONE 17 Sep 2019

Typhoid Fever

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