Vaccine

A vaccine is a biological preparation that improves immunity to a particular disease. A vaccine typically contains an agent that resembles a disease-causing microorganism, and is often made from weakened or killed forms of the microbe. The agent stimulates the body's immune system to recognize the agent as foreign, destroy it, and "remember" it, so that the immune system can more easily recognize and destroy any of these microorganisms that it later encounters.

Aluminum in Vaccines: Mechanisms, Myths, and Safety Data

This article explains how aluminum adjuvants work in vaccines, their proven safety record, and addresses common myths and scientific findings. It also highlights new developments in vaccine adjuvant technology and the ongoing need for rigorous monitoring.

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A New Breed of Vaccine: Exploring Doggybone ™ DNA Technology

What is a Live-Attenuated Vaccine?

The Future of Vaccines

Investigating the Importance of Investing in Vaccine Manufacturing

Could there be a Salmonella Vaccine?

Hib Immunization

What are the Different Types of Vaccines?

What is a Toxoid Vaccine?

What is a DNA Vaccine?

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How Veterinary Vaccines Affect Human Health

Transforming Vaccine Design: The Promise of Systems Biology

Vaccine History

Vaccine Schedule

What is an Inactivated Vaccine?

What the Newest mRNA Vaccines Could Do Beyond COVID

Vaccine Excipients

Role of Computer Modeling in Vaccine Development

Vaccine Delivery

What are Adenovirus-Based Vaccines?

History of Vaccination

What is a Vaccine Breakthrough?

Insight into Personalized Vaccines

Vaccination in Humanitarian Settings

Vaccine Immunity

What is a Non-Replicating Vaccine?

What is a Subunit Vaccine?

The Big Catch-Up: How the COVID-19 pandemic impacted vaccination coverage

Vaccine Effectiveness

What is a VLP Vaccine?

The Essential Program on Immunization is 50: Milestones, achievements, and future directions

Plant-Derived Vaccines

Vaccine Production

How are Vaccines Stored?

What are the Main Causes of Vaccine Hesitancy?

What is an RNA Vaccine?

What are Nanoparticle-Based Vaccines?

What is the Importance of Vaccination Coverage?

What are Vaccines?

Latest Vaccine News and Research

WashU study identifies shared target for a new diarrhea vaccine

The bacteria enterotoxigenic E. coli and Shigella together cause hundreds of millions of infections each year and are among the leading causes of diarrheal death, especially in children.

17 Jun 2026

Houston Methodist study reveals how strep bacterium causes infection

A fast-rising strep bacterium has become increasingly notorious for causing serious infections in humans, including complications that can lead to muscle damage and patient death. New Houston Methodist research appearing in The American Journal of Pathology, published by Elsevier, sheds light on how Streptococcus dysgalactiae subspecies equisimilis (SDSE) causes disease and may provide important insights to aid in vaccine development.

17 Jun 2026

Targeted vaccination strategies strengthen global biosecurity and biosafety

Biosafety prevents biohazard risks to humans and the environment, biosecurity protects biological assets from misuse, and One Health is an interdisciplinary framework uniting human, animal, and environmental health—all core to global health protection.

17 Jun 2026

Maternal RSV vaccine shows 68% protection against infant RSV hospitalization

In a test-negative case-control study of 274 hospitalized infants aged 90 days or younger, maternal RSVpreF vaccination was associated with 67.6% effectiveness against RSV-associated acute respiratory illness hospitalization. Protection was similar against RSV-linked lower respiratory tract disease, with the highest point estimate in the first month of life, although confidence intervals were wide.

16 Jun 2026

New mRNA flu vaccine offers broader protection against influenza strains

A new study led by researchers at Washington University School of Medicine in St. Louis has found that an investigational mRNA influenza vaccine helps the immune system recognize a wider range of influenza viruses than today's standard flu shot, offering stronger and potentially longer-lasting protection.

15 Jun 2026

Australia’s diphtheria outbreak shows why boosters, antibiotics, and better housing all matter

A 131-case diphtheria outbreak in Australia’s Northern Territory showed how toxigenic Corynebacterium diphtheriae can re-emerge even in highly vaccinated populations. Genomic and epidemiological evidence linked most cases to a dominant ST381 strain, with transmission shaped by overcrowding, poor skin health, and persistent health inequities.

15 Jun 2026

New poll reveals how politics reshaped trust in U.S. public health

A Harvard Chan/de Beaumont national poll of 2,205 U.S. adults found CDC trust dropped to 50% one year into new federal public health leadership, while state and local health agencies remained more trusted.

14 Jun 2026

New poll reveals political divide over public water fluoridation

As the debate over the value of adding fluoride to public drinking water percolates in communities across the nation, a new nationally representative survey from the Annenberg Public Policy Center (APPC) of the University of Pennsylvania finds Americans sharply divided over the use of fluoride in public drinking water.

12 Jun 2026

Antibody profiles offer insights into long Covid cognitive symptoms

Persistent symptoms after COVID-19 infection continue to affect millions of people worldwide, even as the number of acute infections has declined.

12 Jun 2026

Experimental vaccine protects against fentanyl and related opioids

Fentanyl and related variants of the synthetic opioid kill more Americans each year than car accidents and gun violence combined. In too-high doses, the drugs hijack brain chemistry and shut down the signals that control breathing.

11 Jun 2026

Leading AI models ace many vaccine questions but falter on clinical rules

A multilingual benchmark of 1,886 vaccine-related questions found that large language models answered most items accurately across English, Spanish, and Chinese. However, performance varied by vaccine type, language, and prompting method, with persistent errors in dosing, contraindications, age eligibility, and other clinically sensitive guidance.

11 Jun 2026

Single-dose vaccine provides complete protection against Andes hantavirus

In a study published in The Lancet, researchers at The University of Texas Medical Branch (UTMB) report the development of new vaccines that, in animal testing, provided full protection against the deadly Andes hantavirus after a single dose.

11 Jun 2026

Researchers track how chronic wasting disease spreads to other species

Chronic wasting disease (CWD) is generally associated with animals. But a new study by researchers from the University of Calgary and international collaborators explored the potential for CWD to spread from deer, elk and other cervid (hooved, plant-eating) animals to other species.

11 Jun 2026

Key proteins enable louse-borne relapsing fever pathogen to evade immunity

Louse-borne relapsing fever is caused by the spirochete bacterium Borrelia recurrentis, which is transmitted by body lice (not head lice).

10 Jun 2026

Public health messaging still beats AI chatbots for HPV vaccine promotion

The study finds that AI chatbots boost HPV vaccination intent temporarily, but public health resources are crucial for lasting impact on vaccination decisions.

10 Jun 2026

AI-powered chatbots no better than written public health materials for vaccine promotion

A new Penn-led randomized controlled trial has found that AI-powered chatbots can make vaccine-hesitant parents more likely to say they will immunize their children against human papillomavirus (HPV), but no more than standard written public health materials.

9 Jun 2026

Experimental two‑in‑one vaccine shows success in human LASSARAB trial

Researchers from Thomas Jefferson University and the University of Maryland School of Medicine have reported encouraging results from the first human clinical trial of LASSARAB, an experimental vaccine designed to protect against Lassa fever and rabies in a single formulation.

9 Jun 2026

How Programmable Nanobiology Could Drive the Fifth Industrial Revolution

Professor Heddle's insights on nanobiology and AI highlight their potential to innovate drug delivery and vaccine development, addressing critical health needs.

9 Jun 2026

Study links menstrual cycle timing to COVID vaccine side effects

A study of 1,474 Clue app users found that women vaccinated against COVID-19 during the follicular phase had higher odds of self-reported side effects than those vaccinated during the luteal phase.

8 Jun 2026

New project launches to advance chikungunya vaccine in Africa

Funded by the Global Health EDCTP3 Joint Undertaking, a new €15.3 million project coordinated by Institut Pasteur brings together seven partners across four continents to advance clinical trials and prepare for the manufacturing of a chikungunya vaccine in Africa.

8 Jun 2026