Vaccine

A vaccine is a biological preparation that improves immunity to a particular disease. A vaccine typically contains an agent that resembles a disease-causing microorganism, and is often made from weakened or killed forms of the microbe. The agent stimulates the body's immune system to recognize the agent as foreign, destroy it, and "remember" it, so that the immune system can more easily recognize and destroy any of these microorganisms that it later encounters.

Aluminum in Vaccines: Mechanisms, Myths, and Safety Data

This article explains how aluminum adjuvants work in vaccines, their proven safety record, and addresses common myths and scientific findings. It also highlights new developments in vaccine adjuvant technology and the ongoing need for rigorous monitoring.

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Vaccination in Humanitarian Settings

What are the Different Types of Vaccines?

What are Adenovirus-Based Vaccines?

Vaccine Delivery

Vaccine Production

What are Nanoparticle-Based Vaccines?

Investigating the Importance of Investing in Vaccine Manufacturing

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The Future of Vaccines

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What is a VLP Vaccine?

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Hib Immunization

What the Newest mRNA Vaccines Could Do Beyond COVID

What is an RNA Vaccine?

Vaccine Immunity

How are Vaccines Stored?

What is a Non-Replicating Vaccine?

What is a DNA Vaccine?

A New Breed of Vaccine: Exploring Doggybone ™ DNA Technology

Vaccine Schedule

The Big Catch-Up: How the COVID-19 pandemic impacted vaccination coverage

What is a Subunit Vaccine?

History of Vaccination

What is an Inactivated Vaccine?

Vaccine Excipients

What are Vaccines?

Insight into Personalized Vaccines

Plant-Derived Vaccines

Immunization strategies: What lessons can we learn from successful campaigns?

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Latest Vaccine News and Research

Organ-on-a-chip system reveals how aging weakens vaccine-driven anti-cancer immunity

Dr. Vadim Jucaud's lab at the Terasaki Institute has introduced a new organ-on-a-chip platform that recapitulates age-dependent immune responses, offering a more accurate testing bed for evaluating cancer vaccine performance in older adults, the population most affected by cancer and often overlooked in traditional preclinical testing.

4 Dec 2025

Single-dose dengue vaccine will benefit populations in hard-to-reach regions

A world-first single-dose vaccine against the dengue virus, manufactured and approved for use in Brazil, will especially benefit populations in hard-to-reach regions of the country such as the Amazon, say disease specialists.

4 Dec 2025

Injectable scaffold vaccine shows strong protection against implant-related MRSA

Research reveals that silica scaffolds can train the immune system against S. aureus, offering a novel approach to prevent orthopedic device infections.

4 Dec 2025

New rapid test distinguishes real HIV infections from vaccine-related false positives

Since the human immunodeficiency virus (HIV) was identified in 1983, roughly 91.4 million people around the world have contracted the virus and an additional 44.1 million have died from related causes.

3 Dec 2025

Americans trust AMA over CDC on vaccine safety

For decades, health-related statements by major professional health associations such as the American Medical Association (AMA) agreed with those of the Centers for Disease Control and Prevention (CDC) because both relied on the same body of scientific knowledge, much of it funded by the federal health sector.

3 Dec 2025

Shingles vaccine may benefit individuals already diagnosed with dementia, new study finds

An unusual public health policy in Wales may have produced the strongest evidence yet that a vaccine can reduce the risk of dementia.

2 Dec 2025

Pneumococcal vaccination lowers antibiotic-resistant bacteria in children

Children in Guatemala who received a common vaccine that helps prevent pneumonia were less likely to carry antibiotic-resistant bacteria, according to a new study led by Washington State University researchers.

2 Dec 2025

WHO urges action to end the AIDS epidemic

On World AIDS Day, the World Health Organization (WHO) calls on governments and partners to rapidly expand access to new WHO-approved tools including lenacapavir (LEN) to drive down infections and counter disruption to essential health services caused by cuts to foreign aid.

2 Dec 2025

RFK Jr. wants to delay the hepatitis B vaccine. Here’s what parents need to know.

Working out of a tribal-owned hospital in Anchorage, Alaska, liver specialist Brian McMahon has spent decades treating the long shadow of hepatitis B. Before a vaccine became available in the 1980s, he saw the virus claim young lives in western Alaskan communities with stunning speed.

2 Dec 2025

Combination immunotherapy may be the key to control HIV without long-term antiviral treatment

A new study from UC San Francisco shows it may be possible to control HIV without long-term antiviral treatment - an advance that points the way toward a possible cure for a disease that affects 40 million people around the world.

1 Dec 2025

Measles deaths plummet but infections surge worldwide

Global immunization efforts have led to an 88% drop in measles deaths between 2000 and 2024, according to a new report from the World Health Organization (WHO). Nearly 59 million lives have been saved by the measles vaccine since 2000.

29 Nov 2025

Regional crises and climate shocks drive global resurgence of cholera

Cholera, caused by Vibrio cholerae, spreads through contaminated water and thrives where sanitation systems have collapsed. Once inside the body, it dehydrates victims within hours, but with prompt treatment, nearly every life can be saved.

27 Nov 2025

Global Virus Network outlines priorities as Marburg virus emerges in Ethiopia

The Global Virus Network (GVN), a coalition of leading human and animal virologists in more than 40 countries dedicated to advancing pandemic preparedness through research, education and training, and global health solutions, today issued a statement on the newly confirmed outbreak of Marburg virus disease (MVD) in southern Ethiopia.

27 Nov 2025

Tattoo ink alters immune cells and weakens some vaccine responses

New research shows tattoo pigments migrate to lymph nodes, causing inflammation and altering immune responses to vaccines, with potential health risks.

27 Nov 2025

Year-round access to RSV immunization may reduce major seasonal outbreaks

Providing year-round access to RSV immunization would minimize the risk of large seasonal outbreaks across the nation, including in both urban and rural areas.

26 Nov 2025

South Carolina’s measles outbreak shows chilling effect of vaccine misinformation

Near the back corner of the local library's parking lot, largely out of view from the main road, the South Carolina Department of Public Health opened a pop-up clinic in early November, offering free measles vaccines to adults and children.

26 Nov 2025

'Mental model' approach shown to reduce effects of misinformation about mRNA vaccines

Correcting misinformation after it has gone viral is a common way of informing the public that what they've encountered may be inaccurate, lack context, be unproven, or be demonstrably false.

24 Nov 2025

Study introduces cost-effective approach to analyze entire T-cell repertoire

Studying T cells, the immune cells most responsible for responding to infections and cancers, just received a significant boost in the form of a new technique from St. Jude Children's Research Hospital.

24 Nov 2025

Kimchi consumption strengthens antigen recognition and immune regulation

Amid concerns about the simultaneous spread of multiple respiratory diseases, such as colds and influenza, with the change of seasons in current times, a recent clinical study has scientifically proven that kimchi, a traditional Korean fermented food, enhances the function of human immune cells and maintains the balance of the immune system.

24 Nov 2025

New Cochrane reviews confirm the effectiveness of HPV vaccines in preventing cervical cancer

Two new Cochrane reviews show strong and consistent evidence that HPV vaccines are effective in preventing cervical cancer and pre-cancerous changes, especially when given to young people before they are exposed to the virus.

24 Nov 2025