Vaccine

A vaccine is a biological preparation that improves immunity to a particular disease. A vaccine typically contains an agent that resembles a disease-causing microorganism, and is often made from weakened or killed forms of the microbe. The agent stimulates the body's immune system to recognize the agent as foreign, destroy it, and "remember" it, so that the immune system can more easily recognize and destroy any of these microorganisms that it later encounters.

Aluminum in Vaccines: Mechanisms, Myths, and Safety Data

This article explains how aluminum adjuvants work in vaccines, their proven safety record, and addresses common myths and scientific findings. It also highlights new developments in vaccine adjuvant technology and the ongoing need for rigorous monitoring.

The Essential Program on Immunization is 50: Milestones, achievements, and future directions

What are Adenovirus-Based Vaccines?

Vaccination in Humanitarian Settings

What the Newest mRNA Vaccines Could Do Beyond COVID

What are Nanoparticle-Based Vaccines?

Vaccine History

A New Breed of Vaccine: Exploring Doggybone ™ DNA Technology

Role of Computer Modeling in Vaccine Development

What is a Subunit Vaccine?

Plant-Derived Vaccines

Vaccine Production

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The Big Catch-Up: How the COVID-19 pandemic impacted vaccination coverage

What is an RNA Vaccine?

What is a DNA Vaccine?

History of Vaccination

How are Vaccines Stored?

What is Immunobridging?

Vaccine Delivery

Hib Immunization

Vaccine Immunity

Transforming Vaccine Design: The Promise of Systems Biology

What are Vaccines?

The Future of Vaccines

Immunization strategies: What lessons can we learn from successful campaigns?

Vaccine Schedule

How Veterinary Vaccines Affect Human Health

Vaccine Effectiveness

Insight into Personalized Vaccines

What is a Toxoid Vaccine?

Vaccine Excipients

What is a Vaccine Breakthrough?

What is a VLP Vaccine?

What are the Main Causes of Vaccine Hesitancy?

What is the Importance of Vaccination Coverage?

What are the Different Types of Vaccines?

Investigating the Importance of Investing in Vaccine Manufacturing

What is a Non-Replicating Vaccine?

What is a Live-Attenuated Vaccine?

Could there be a Salmonella Vaccine?

What is an Inactivated Vaccine?

Latest Vaccine News and Research

Updated clinical guideline offers strategies to reduce vaccination distress

A comprehensive guideline update with 16 recommendations to reduce vaccination distress, with suggestions ranging from applying topical pain relief to distractions, has been published in the Canadian Medical Association Journal.

21 Sep 2026

New brain circuit discovery offers hope for panic disorder treatments

Our survival depends on brains that constantly search for danger and, if found, stay alert until it has passed.

21 Sep 2026

World Cup travel and low vaccination fuel Latin American measles outbreaks

Countries in Latin America are being urged to strengthen vaccination and surveillance to fight measles as the region records the highest number of cases in more than two decades, disease experts say.

21 Sep 2026

Congo faces unprecedented Ebola outbreak without approved vaccine protection

As the Ebola outbreak spreads unabated in the Democratic Republic of the Congo (DRC), vaccine developers are scrambling to develop and test a vaccine candidate that will target the species at its center.

21 Sep 2026

Measles outbreaks may reveal more than gaps in vaccination

A commentary in Human Vaccines & Immunotherapeutics argues that measles outbreaks can serve as a sensitive indicator of weaknesses in vaccination coverage, surveillance, health equity, community trust, and broader immunization systems. The authors contend that pursuing measles eradication could also strengthen routine immunization, laboratory capacity, outbreak preparedness, and health-system resilience.

21 Sep 2026

A 194-country analysis reveals gaps in how late childhood vaccinations are tracked

A global analysis of WHO/UNICEF data from 194 countries found wide variation in countries’ ability to record delayed childhood vaccinations, with 64% of reporting countries saying they could capture late doses in 2022. Following birth cohorts over time and adding delayed MCV1 doses raised median coverage estimates by 3.6 to 5.1 percentage points across available cohort years, though incomplete and inconsistent reporting limited confidence in some estimates.

21 Sep 2026

New mRNA vaccine expands flu protection options for older adults

Every fall, millions of Americans heed the call to get their annual flu shot. Getting vaccinated reduces the risk of severe illness, hospitalization, and death from influenza.

20 Sep 2026

HIV awareness emphasizes prevention, treatment and healthy aging

About 1.2 million people in the United States are living with HIV, or human immunodeficiency virus. Because of major advances in medical treatment and technology, people with HIV are living long, healthy lives.

18 Sep 2026

Global Virus Network monitors spreading avian influenza in Australian mammals

The Global Virus Network (GVN) is closely monitoring detections of highly pathogenic avian influenza A (H5N1), commonly known as bird flu, in several mammal species in Australia as the virus continues to spread among birds and mammals worldwide.

18 Sep 2026

Chile becomes first South American nation to eliminate dog-transmitted rabies

Chile has become the first country in South America to receive the World Health Organization (WHO) validation for eliminating dog-transmitted rabies as a public health problem.

18 Sep 2026

US health officials knowingly relied on flawed vaccine safety algorithm

US health officials knowingly relied on a compromised algorithm to detect signals of harm from mRNA covid-19 vaccines and silenced efforts to fix it, finds an investigation published by The BMJ today.

17 Sep 2026

Immunotherapy combined with BCG vaccine drastically lowers tuberculosis relapse risk

Tuberculosis (TB) remains one of the world's leading causes of death, and preventing post-treatment relapse continues to be a major worldwide health challenge.

17 Sep 2026

Innate immune system variations determine vaccine side effects

Redness and pain at the injection site, fever, fatigue or headaches: vaccines can cause side effects, but their frequency and severity vary considerably from person to person.

17 Sep 2026

Single-molecule imaging reveals nucleated growth mechanism of viral capsids

Oxford University researchers have captured the step-by-step assembly of individual virus-like particles, revealing how simple molecular interactions can reliably build these complex biological structures. The results have been published today (16 September) in Nature.

17 Sep 2026

Salk scientists demonstrate B cells directly enhance killer T cell function

Cancer is the second leading cause of death in the United States, according to a 2026 Cancer Research Institute report. Cancer biologists are keenly aware of this statistic, as it drives them to innovations that revolutionize cancer care-innovations like immunotherapy.

17 Sep 2026

Hedgehog coronaviruses reveal potential pathways for cross-species transmission

Washington State University researchers have discovered how a group of coronaviruses circulating in hedgehogs invades host cells, a key to understanding their potential to jump between species and their risk of causing a pandemic in humans.

16 Sep 2026

Study confirms continued effectiveness of antibodies and vaccines used to prevent RSV infections

An analysis of more than 60,000 respiratory syncytial virus (RSV) sequences from around the world found that viral variants associated with resistance to current RSV prevention tools remain rare, according to a study published Sept. 16 in Nature.

16 Sep 2026

New AACR report outlines future of cutting-edge cancer research

Today, the American Association for Cancer Research (AACR) released the 16th edition of its annual Cancer Progress Report.

16 Sep 2026

Harvard scientists design evolutionary traps to stop viral mutations

When a virus mutates, the world usually finds out the hard way. Variants of influenza and SARS‑CoV‑2 can slip past vaccines and antibody drugs before scientists fully understand what has changed.

15 Sep 2026

Insilico Medicine launches AI initiative to develop longevity vaccines

Insilico Medicine, a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, today announced Longevity Vaccines, a research initiative developing treatments that direct a patient's own immune cells to eliminate the earliest cellular drivers of age-related disease.

15 Sep 2026