Vaccine

A vaccine is a biological preparation that improves immunity to a particular disease. A vaccine typically contains an agent that resembles a disease-causing microorganism, and is often made from weakened or killed forms of the microbe. The agent stimulates the body's immune system to recognize the agent as foreign, destroy it, and "remember" it, so that the immune system can more easily recognize and destroy any of these microorganisms that it later encounters.

Aluminum in Vaccines: Mechanisms, Myths, and Safety Data

This article explains how aluminum adjuvants work in vaccines, their proven safety record, and addresses common myths and scientific findings. It also highlights new developments in vaccine adjuvant technology and the ongoing need for rigorous monitoring.

Immunization strategies: What lessons can we learn from successful campaigns?

What is a Vaccine Breakthrough?

How are Vaccines Stored?

What is a Toxoid Vaccine?

What is Immunobridging?

What is an RNA Vaccine?

What is a Subunit Vaccine?

Vaccine Production

What is the Importance of Vaccination Coverage?

What are the Main Causes of Vaccine Hesitancy?

What are the Different Types of Vaccines?

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What is a DNA Vaccine?

Investigating the Importance of Investing in Vaccine Manufacturing

What is an Inactivated Vaccine?

Vaccination in Humanitarian Settings

The Future of Vaccines

What are Adenovirus-Based Vaccines?

History of Vaccination

What are Nanoparticle-Based Vaccines?

Vaccine Immunity

Transforming Vaccine Design: The Promise of Systems Biology

A New Breed of Vaccine: Exploring Doggybone ™ DNA Technology

What are Vaccines?

Vaccine Schedule

Hib Immunization

What the Newest mRNA Vaccines Could Do Beyond COVID

Insight into Personalized Vaccines

Vaccine Delivery

Could there be a Salmonella Vaccine?

Plant-Derived Vaccines

Vaccine Effectiveness

Vaccine Excipients

What is a Non-Replicating Vaccine?

The Essential Program on Immunization is 50: Milestones, achievements, and future directions

What is a VLP Vaccine?

Role of Computer Modeling in Vaccine Development

How Veterinary Vaccines Affect Human Health

Vaccine History

The Big Catch-Up: How the COVID-19 pandemic impacted vaccination coverage

What is a Live-Attenuated Vaccine?

Latest Vaccine News and Research

Single DNA injection provides long-lasting weight loss in mouse study

Scientists at The Wistar Institute have shown that a single injection of a small, circular piece of genetic instructions can produce weight loss and blood glucose control in murine models that lasts up to 10 times as long as incretin-mimicking drugs like Ozempic and Wegovy.

26 Jun 2026

Yale study offers critical clues for future norovirus treatments

As the leading cause of viral gastroenteritis worldwide, norovirus is an all too familiar ailment. Its telltale digestive upset — not to mention its reputation for being notoriously contagious — has earned it the nicknames "winter vomiting bug" and "stomach flu."

26 Jun 2026

Engineered CAR T cells successfully target bladder cancer in mice

Researchers at Weill Cornell Medicine, Cedars-Sinai Medical Center, and Roswell Park Comprehensive Cancer Center have developed genetically engineered CAR T cells that specifically target and kill bladder cancer cells.

26 Jun 2026

Rare Ebola strain may spread beyond Congo, study warns

A rare strain of Ebola that began spreading undetected in eastern Democratic Republic of Congo (DRC) in early April 2026 has now confirmed transmission in Uganda and is potentially on course to reach South Sudan, according to a new modelling study from the World Health Organization (WHO) published in The Lancet Infectious Diseases journal.

25 Jun 2026

Iron overload gradually increases neurons' vulnerability to neurodegeneration

Neurodegenerative diseases affect tens of millions of people worldwide. Among these, Alzheimer's and Parkinson's diseases are the most common; in the United States alone, the Alzheimer's Disease Association and Parkinson's Foundation report roughly 7 million people with Alzheimer's and another million with Parkinson's.

25 Jun 2026

Spermidine supplement improves COVID 19 vaccine response in older adults

As we age, the immune system gradually declines and becomes less effective at responding to infections and vaccines.

25 Jun 2026

Research may help pave the way for new vaccine targeting diarrheal disease

Research led by the University of Bergen (UiB) and NORCE may help pave the way for a new vaccine targeting one of the world's leading causes of severe diarrheal disease.

25 Jun 2026

US study shows updated COVID vaccines cut hospitalization odds by 55%

The 2025-2026 COVID-19 vaccines were associated with 50% estimated effectiveness against COVID-19-associated emergency department and urgent care encounters among immunocompetent US adults. They were also linked to an estimated 55% effectiveness against COVID-19-associated hospitalization, providing added protection beyond existing immunity from prior infection or vaccination.

24 Jun 2026

Study outlines legal challenges for fetal tissue research in Japan

Human fetal tissue research has contributed to advances in developmental biology, the study of congenital diseases, regenerative medicine, and vaccine development.

24 Jun 2026

Prime and pull vaccine approach prevents genital herpes infection

Genital herpes is a lifelong infection. While available treatments can manage symptoms, they cannot cure the infection or prevent transmission.

22 Jun 2026

Scientists discover protective antibodies with potential to treat West Nile virus

West Nile virus (WNV) is transmitted by mosquitoes and is increasingly relevant for Europe and worldwide. It can cause severe brain infection and death, yet there is no specific antiviral treatment or approved human vaccine.

22 Jun 2026

New vaccines successfully boost frontline immune cells against HIV

T-cells are the immune system's frontline defenders with a crucial role in controlling HIV. In a milestone clinical trial published in the Journal of Clinical Investigation, researchers with the UNC Institute for Global Health and Infectious Diseases (IGHID) at the UNC School of Medicine have demonstrated that new vaccines can significantly boost T cells targeting the most vulnerable, conserved regions of HIV-areas considered key to effective immune control.

22 Jun 2026

How clinicians can identify and manage Ebola, hantavirus

Two deadly infectious diseases, Ebola https://www.cmaj.ca/lookup/doi/10.1503/cmaj.260834 and hantavirus https://www.cmaj.ca/lookup/doi/10.1503/cmaj.260789, have made headlines in recent weeks as they pose serious threats to public health.

22 Jun 2026

Aging immune cells may explain why autoimmunity rises later in life

A new Review reveals how aging can push the immune system into a paradoxical state, weaker against threats yet more prone to attacking the body’s own tissues.

21 Jun 2026

HPV vaccination linked to sharp decline in cervical cancer deaths

High-income countries that initiated widespread administration of the Human Papilloma Virus (HPV) vaccine in the mid-2000s have experienced substantial declines in cervical cancer cases, marking a significant achievement in medicine.

18 Jun 2026

New mRNA vaccine shrinks neuroblastoma tumors in preclinical study

A new study from RCSI University of Medicine and Health Sciences demonstrates a novel approach in anticancer vaccine development. Results present the first preclinical evidence to show the efficacy of an mRNA vaccine in targeting neuroblastoma, the deadliest childhood cancer.

18 Jun 2026

Scientists design artificial protein structures using advanced AI tools

An international research team led by a Korean scientist has succeeded in designing large-scale protein structures that faithfully replicate the self-assembly principles found in naturally occurring viruses, using artificial intelligence (AI).

18 Jun 2026

Emergency departments could help boost annual flu vaccination rates

A University of California, Riverside-led study of more than 3,200 emergency department (ED) patients across the United States found that while awareness of influenza vaccination is widespread, most adults seen in EDs are not up to date on their annual flu vaccine.

17 Jun 2026

WashU study identifies shared target for a new diarrhea vaccine

The bacteria enterotoxigenic E. coli and Shigella together cause hundreds of millions of infections each year and are among the leading causes of diarrheal death, especially in children.

17 Jun 2026

Houston Methodist study reveals how strep bacterium causes infection

A fast-rising strep bacterium has become increasingly notorious for causing serious infections in humans, including complications that can lead to muscle damage and patient death. New Houston Methodist research appearing in The American Journal of Pathology, published by Elsevier, sheds light on how Streptococcus dysgalactiae subspecies equisimilis (SDSE) causes disease and may provide important insights to aid in vaccine development.

17 Jun 2026