Vaccine

A vaccine is a biological preparation that improves immunity to a particular disease. A vaccine typically contains an agent that resembles a disease-causing microorganism, and is often made from weakened or killed forms of the microbe. The agent stimulates the body's immune system to recognize the agent as foreign, destroy it, and "remember" it, so that the immune system can more easily recognize and destroy any of these microorganisms that it later encounters.

Aluminum in Vaccines: Mechanisms, Myths, and Safety Data

This article explains how aluminum adjuvants work in vaccines, their proven safety record, and addresses common myths and scientific findings. It also highlights new developments in vaccine adjuvant technology and the ongoing need for rigorous monitoring.

Insight into Personalized Vaccines

What is a Non-Replicating Vaccine?

How Veterinary Vaccines Affect Human Health

What are Nanoparticle-Based Vaccines?

Investigating the Importance of Investing in Vaccine Manufacturing

Transforming Vaccine Design: The Promise of Systems Biology

Vaccine Schedule

What is an RNA Vaccine?

Vaccine Delivery

Vaccine Effectiveness

What is a Toxoid Vaccine?

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What is the Importance of Vaccination Coverage?

What is a DNA Vaccine?

What is Immunobridging?

Vaccine History

What are the Main Causes of Vaccine Hesitancy?

What are Adenovirus-Based Vaccines?

A New Breed of Vaccine: Exploring Doggybone ™ DNA Technology

Vaccine Production

What is a VLP Vaccine?

What is a Subunit Vaccine?

Immunization strategies: What lessons can we learn from successful campaigns?

The Big Catch-Up: How the COVID-19 pandemic impacted vaccination coverage

What is a Live-Attenuated Vaccine?

Vaccine Immunity

Vaccine Excipients

Plant-Derived Vaccines

History of Vaccination

The Future of Vaccines

Hib Immunization

What the Newest mRNA Vaccines Could Do Beyond COVID

Role of Computer Modeling in Vaccine Development

Vaccination in Humanitarian Settings

What are the Different Types of Vaccines?

Could there be a Salmonella Vaccine?

How are Vaccines Stored?

The Essential Program on Immunization is 50: Milestones, achievements, and future directions

What is an Inactivated Vaccine?

What are Vaccines?

What is a Vaccine Breakthrough?

Latest Vaccine News and Research

Weak governance hinders One Health outbreak response in Africa

Across Africa, One Health is endorsed at the top but often breaks down where outbreaks start, writes Albert Ansah.

5 Feb 2026

Expanded vaccine supply allows resumption of cholera prevention campaigns

Global cholera vaccine supply has now increased to a level sufficient to allow the resumption of life-saving preventive campaigns for the first time in over three years, Gavi, the Vaccine Alliance, UNICEF, and the World Health Organization (WHO) announced today.

5 Feb 2026

Study reveals evidence of silent mpox exposure in healthy Nigerians

New evidence suggests that mpox may be circulating quietly among healthy Nigerians, with some infections occurring without the symptoms that typically trigger detection by health authorities.

5 Feb 2026

Gut microbial butyrate enhances mucosal vaccine antibody responses

A research team from POSTECH and ImmunoBiome in Korea, led by Professor Sin-Hyeog Im, has uncovered a new mechanism showing how butyrate-a short-chain fatty acid produced by gut commensal bacteria-enhances T follicular helper (Tfh) cell activity to promote antibody production and strengthen mucosal vaccine efficacy.

4 Feb 2026

Breakthrough enables continuous laboratory growth of human norovirus

Researchers at Baylor College of Medicine report in Science Advances a breakthrough in human norovirus (HuNoV) research.

4 Feb 2026

COVID vaccination not linked to reduced childbirth

COVID-19 vaccination is not the cause behind a decrease in childbirth, according to a study from Linköping University, Sweden.

4 Feb 2026

Poll: Many adults over 50 skip flu and COVID vaccines

This winter's brutal flu season isn't over, and COVID-19 cases have risen recently too. But a new poll taken in recent weeks shows that vaccination against both viruses lags among people 50 and over, and the national survey reveals key reasons why.

3 Feb 2026

Single-dose HIV vaccine candidate induces neutralizing antibodies

Scientists at The Wistar Institute have developed an HIV vaccine candidate that achieves something never before observed in the field: inducing neutralizing antibodies against HIV after a single immunization in nonhuman primates.

3 Feb 2026

Six years after COVID-19: Lessons learned and pandemic preparedness

Six years ago, the Director-General of the World Health Organization sounded the highest global alarm available under international law at the time, declaring the outbreak of a new coronavirus disease (later known as COVID-19) a Public Health Emergency of International Concern (PHEIC).

3 Feb 2026

Clinical trial launched to test experimental intranasal spray against respiratory viruses

Last year, at least one million people in the U.S. were hospitalized for respiratory virus illnesses like the flu or COVID-19, according to the Centers for Disease Control and Prevention.

2 Feb 2026

How the CDC prepares influenza vaccines for pandemics

CDC scientists outline the comprehensive methodology involved in the development of influenza candidate vaccine viruses.

2 Feb 2026

Nasal spray vaccine prevents infection from highly pathogenic H5N1 virus

Researchers at WashU Medicine have developed a nasal vaccine against the highly pathogenic H5N1 avian influenza virus, or bird flu, which has jumped from wild birds to livestock to humans.

30 Jan 2026

New diagnostic framework addresses challenges of rapidly-mutating RNA viruses

The rapid evolutionary dynamics of RNA viruses, driven by high mutation rates and the consequent formation of complex quasispecies populations, present a formidable obstacle to conventional molecular diagnostic approaches.

30 Jan 2026

Sino Biological expands research reagent portfolio to support global Nipah virus vaccine and diagnostic development

Recent reports of Nipah virus (NiV) infections in West Bengal, India, have reignited global concern, prompting public health authorities to prioritize research into this high-mortality pathogen.

From Sino Biological Inc. 30 Jan 2026

Genetic inheritance and life experience leave distinct epigenetic marks in immune cells

The COVID-19 pandemic gave us tremendous perspective on how wildly symptoms and outcomes can vary between patients experiencing the same infection.

29 Jan 2026

Two-pronged therapeutic technology for cancer wins Pfizer Prize for Biomedical Research 2026

Whereas conventional treatments such as chemotherapy and radiotherapy show their limitations in battling certain advanced cancers, immunotherapy and therapeutic vaccines have opened up a new realm of hope for patients.

29 Jan 2026

Older adults' driving habits may provide early warning signs of cognitive decline or dementia

Older adults' driving habits revealed clues about their brain health and may provide early warning signs of cognitive decline or dementia, according to a preliminary study to be presented at the American Stroke Association's International Stroke Conference 2026.

29 Jan 2026

Her son’s injury never got its day in vaccine court. Their lawyer is now advising RFK on its overhaul.

In 2019, after a routine vaccination, 11-year-old Keithron Thomas felt a sharp pain in his shoulder and down his arm. His mother, Melanie Bostic, thought it would go away after a few days. But days turned to weeks, then months, and years.

29 Jan 2026

How DNA and life experiences leave distinct marks on the human immune system

Using single-cell epigenomic profiling of immune cells from 110 individuals, researchers show that genetic variation and environmental exposures shape the human immune system through distinct DNA methylation mechanisms. Genetic effects concentrate within gene bodies of memory cells, while environmental exposures primarily remodel regulatory regions in naive immune cells.

28 Jan 2026

UVA Health scientists pioneer a new way to create vaccines far more quickly than ever before

UVA Health scientists are reporting promising success as they pioneer a new way to create vaccines far more quickly, nimbly and inexpensively than ever before.

28 Jan 2026