Vaccine

A vaccine is a biological preparation that improves immunity to a particular disease. A vaccine typically contains an agent that resembles a disease-causing microorganism, and is often made from weakened or killed forms of the microbe. The agent stimulates the body's immune system to recognize the agent as foreign, destroy it, and "remember" it, so that the immune system can more easily recognize and destroy any of these microorganisms that it later encounters.

Aluminum in Vaccines: Mechanisms, Myths, and Safety Data

This article explains how aluminum adjuvants work in vaccines, their proven safety record, and addresses common myths and scientific findings. It also highlights new developments in vaccine adjuvant technology and the ongoing need for rigorous monitoring.

How Veterinary Vaccines Affect Human Health

What is a Toxoid Vaccine?

What are the Different Types of Vaccines?

Vaccine Effectiveness

What is the Importance of Vaccination Coverage?

Plant-Derived Vaccines

Vaccine Schedule

What is an RNA Vaccine?

Insight into Personalized Vaccines

What are the Main Causes of Vaccine Hesitancy?

Vaccine Production

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Vaccine History

What is a VLP Vaccine?

Hib Immunization

Transforming Vaccine Design: The Promise of Systems Biology

What is Immunobridging?

What is a DNA Vaccine?

Vaccine Immunity

Immunization strategies: What lessons can we learn from successful campaigns?

The Essential Program on Immunization is 50: Milestones, achievements, and future directions

What is a Vaccine Breakthrough?

What are Nanoparticle-Based Vaccines?

How are Vaccines Stored?

Vaccination in Humanitarian Settings

Vaccine Delivery

Role of Computer Modeling in Vaccine Development

What is a Non-Replicating Vaccine?

Vaccine Excipients

A New Breed of Vaccine: Exploring Doggybone ™ DNA Technology

What is a Live-Attenuated Vaccine?

What are Vaccines?

The Big Catch-Up: How the COVID-19 pandemic impacted vaccination coverage

What is an Inactivated Vaccine?

History of Vaccination

Investigating the Importance of Investing in Vaccine Manufacturing

What are Adenovirus-Based Vaccines?

What is a Subunit Vaccine?

Could there be a Salmonella Vaccine?

What the Newest mRNA Vaccines Could Do Beyond COVID

The Future of Vaccines

Latest Vaccine News and Research

Researchers uncover new mechanism linking metabolism, immunity, and skeletal health

Obesity alters bone health not only through increased body weight but also by reshaping the bone marrow environment.

25 Apr 2026

WHO reports measurable health gains but warns of unmet goals

The World Health Organization (WHO) today released its Results Report, highlighting measurable improvements in people's health worldwide in 2025, despite funding cuts affecting both the organization and the broader global health sector.

24 Apr 2026

The Big Catch-Up reaches millions of children with life-saving vaccines

The Big Catch-Up (BCU), a historic multi-year, multi-country effort to address vaccination declines driven largely by the COVID-19 pandemic, has reached an estimated 18.3 million children aged 1 to 5 across 36 countries with more than 100 million doses of life-saving vaccines, helping to narrow critical immunity gaps, announced Gavi, the Vaccine Alliance (Gavi), WHO, and UNICEF at the start of World Immunization Week.

24 Apr 2026

Air quality in infancy may fundamentally shape long-term immune development

Ambient air pollution is associated with respiratory infection burden in the first year of life, according to preliminary findings from the Immune Development in Early Life (IDEaL) Rome Cohort. Findings from the cohort will be presented during the Pediatric Academic Societies (PAS) 2026 Meeting, taking place April 24-27 in Boston.

24 Apr 2026

Study highlights the fragility of measles elimination in the United States

A new study examined measles vaccination coverage following a large postelimination outbreak, primarily affecting unvaccinated children. Findings from the study will be presented during the Pediatric Academic Societies (PAS) 2026 Meeting, taking place April 24-27 in Boston.

24 Apr 2026

Innovative light probes allow real-time visualization of cellular processes

Fluorescent proteins have revolutionized science, enabling researchers to tag and visualize individual molecules in living cells, tissues, and animals.

23 Apr 2026

Virtual neurology visits match in-person care outcomes

For people who see a neurology clinician for the first time, a new study has found that being seen virtually vs. in-person made no difference in how soon they needed more care.

22 Apr 2026

New antibody mechanism selectively suppresses harmful immune responses

The immune system is our frontline protection against infection, continually searching for and destroying unknown pathogens.

22 Apr 2026

Rising rotavirus cases highlight importance of childhood vaccination

With a rising number of rotavirus cases being reported across the country and in New Jersey this spring, experts from Hackensack Meridian Children's Health are urging parents to ensure their children are vaccinated against this common and potentially severe illness.

21 Apr 2026

Early immune responses linked to broadly neutralizing antibodies against HIV

Some people living with HIV develop antibodies capable of neutralizing many different strains of the virus. New research links this to immune responses that occur early in infection.

21 Apr 2026

AI chatbots give misleading health advice nearly half the time

Widespread inaccuracies in AI chatbot health responses pose public health risks, highlighting the urgent need for better oversight and cleaner training data.

21 Apr 2026

Why Japan saw a major pertussis surge in 2025 while other countries peaked earlier

This study found that pertussis cases fell across Japan, Australia, New Zealand, China, and the USA during COVID-19 restrictions, then resurged afterward, with most countries peaking in 2024 but Japan showing a delayed major outbreak in 2025. In Japan, the surge was concentrated in school-aged children and adolescents, highlighting possible gaps in booster protection and the need to reassess immunization strategies.

20 Apr 2026

Study reveals significant gaps in MMR vaccine knowledge among ER patients

Measles remains one of the most contagious infectious diseases, spread through coughing and sneezing, with even small declines in vaccination coverage leading to outbreaks. As of 2026, California has reported its highest annual measles case count in seven years. In response to this growing concern, researchers have begun examining gaps in measles-related knowledge and vaccination coverage.

20 Apr 2026

What still drives childhood vaccine gaps in the United States

A nationwide analysis of provider-verified NIS-Child data from 2010 to 2023 found that US childhood vaccination coverage remained generally high but was consistently shaped by social and structural factors such as maternal education, income, insurance, language, and region. The study also showed that coverage of the combined seven-vaccine series rose over time, yet persistent disparities remained, especially for vaccines such as influenza, hepatitis A, and rotavirus.

19 Apr 2026

What the Health? From KFF Health News: A new CDC nominee, again

President Donald Trump this week nominated a former deputy surgeon general who has expressed support for vaccines to lead the Centers for Disease Control and Prevention.

17 Apr 2026

Scientists find unexpected immune pathways for mRNA cancer vaccines

The advent of mRNA vaccines against SARS-CoV-2 in 2020 changed the course of the COVID-19 pandemic.

17 Apr 2026

Childhood flu infection leaves lasting immune imprint

A study reveals how childhood flu infections impact long-term mortality risk, highlighting implications for vaccination and future outbreak management.

17 Apr 2026

Superficial skin exposures pose a higher rabies risk than previously thought

While it was previously thought that keratinocytes (skin cells) were only passive conductors that allow the rabies virus to pass through, novel research reveals that these cells play a much more active role. The findings of a new study in the Journal of Investigative Dermatology (JID), published by Elsevier, provide direct evidence that keratinocytes can support viral replication and transmit the rabies virus to neurons. The investigators offer a mechanistic explanation for how superficial skin exposures from scratches or minor bites by dogs and bats can lead to neuroinvasion, contributing to the risk of infection.

16 Apr 2026

New flu vaccine approach targets multiple virus strains

Doctors recommend getting your flu shot annually, since the specific influenza strain it targets varies from year to year. But what if the shot could be more effective while protecting against more strains?

15 Apr 2026

Mitochondrial activity keeps dendritic cells ready to fight disease

Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) show that active mitochondria maintain dendritic cells, the immune system's sentinels, in a "ready-to-respond" state, linking cellular metabolism to gene regulation and T-cell activation.

15 Apr 2026