Vaccine

A vaccine is a biological preparation that improves immunity to a particular disease. A vaccine typically contains an agent that resembles a disease-causing microorganism, and is often made from weakened or killed forms of the microbe. The agent stimulates the body's immune system to recognize the agent as foreign, destroy it, and "remember" it, so that the immune system can more easily recognize and destroy any of these microorganisms that it later encounters.

Aluminum in Vaccines: Mechanisms, Myths, and Safety Data

This article explains how aluminum adjuvants work in vaccines, their proven safety record, and addresses common myths and scientific findings. It also highlights new developments in vaccine adjuvant technology and the ongoing need for rigorous monitoring.

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How Veterinary Vaccines Affect Human Health

Investigating the Importance of Investing in Vaccine Manufacturing

The Essential Program on Immunization is 50: Milestones, achievements, and future directions

What is a Toxoid Vaccine?

The Big Catch-Up: How the COVID-19 pandemic impacted vaccination coverage

What the Newest mRNA Vaccines Could Do Beyond COVID

What are the Different Types of Vaccines?

What is Immunobridging?

Vaccine Delivery

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Could there be a Salmonella Vaccine?

Vaccine Schedule

What is a Live-Attenuated Vaccine?

Vaccine Effectiveness

What are the Main Causes of Vaccine Hesitancy?

What is an Inactivated Vaccine?

What is a Non-Replicating Vaccine?

What are Vaccines?

Vaccine Immunity

Hib Immunization

Immunization strategies: What lessons can we learn from successful campaigns?

Role of Computer Modeling in Vaccine Development

History of Vaccination

How are Vaccines Stored?

Vaccination in Humanitarian Settings

Insight into Personalized Vaccines

What is a Subunit Vaccine?

What is a DNA Vaccine?

Transforming Vaccine Design: The Promise of Systems Biology

What is a VLP Vaccine?

Plant-Derived Vaccines

What is an RNA Vaccine?

A New Breed of Vaccine: Exploring Doggybone ™ DNA Technology

Vaccine History

Vaccine Excipients

The Future of Vaccines

What are Adenovirus-Based Vaccines?

What are Nanoparticle-Based Vaccines?

Vaccine Production

Latest Vaccine News and Research

New laser technique ensures integrity of mRNA therapeutics

Messenger RNA (mRNA) technology is transforming medicine by providing our cells with genetic instructions to produce proteins that help the immune system prevent or fight a wide range of diseases, including cancer and other rare disorders.

26 Feb 2026

Rising vitamin K shot refusal increases newborn brain injury risk

Increasing numbers of parents are refusing vitamin K shots for their newborns, putting infants at greater risk of avoidable brain injuries, according to a preliminary systematic review released February 26, 2026, that will be presented at the American Academy of Neurology's 78th Annual Meeting taking place April 18-22, 2026, in Chicago and online.

26 Feb 2026

Meningococcal B vaccine fails to prevent gonorrhea, trial shows

Contrary to existing evidence from observational studies, the meningococcal B vaccine (4CMenB) has no effect on preventing the acquisition of gonorrhea, according to the results of the world's largest randomized control trial (RCT) into possible efficacy, conducted by Griffith University's Institute for Biomedicine and Glycomics and the Kirby Institute at UNSW Sydney.

25 Feb 2026

Study confirms long-term effectiveness of HPV vaccination

Human papillomavirus (HPV) vaccination is associated with a significantly reduced risk of invasive cervical cancer, with no indication of waning protection up to 18 years after vaccination, finds a study from Sweden published by The BMJ today.

25 Feb 2026

Unexpected behavior observed during interactions between immune cells and dying cells

Over the years, cell biology has built a detailed picture of how cells compartmentalize their internal functions. Central to this organization is the nucleus, which houses the genetic material and is separated from the cytoplasm by a robust nuclear envelope.

25 Feb 2026

Automated platform finds unexpected enhancers for mRNA therapeutics

Integrating AI with advanced robotics to create self-driving labs (SDL) is a promising approach to tackling molecular discovery.

24 Feb 2026

US measles and pertussis outbreaks expose policy failures, not just vaccine hesitancy

A recent commentary argues that US measles and pertussis outbreaks are not simply the result of vaccine hesitancy but reflect weakened immunization policies, permissive exemptions, and underfunded public health systems. The authors contend that policy environments determine whether pockets of low coverage escalate into large-scale, preventable outbreaks.

24 Feb 2026

Hospitals fighting measles confront a challenge: Few doctors have seen it before

At around 2 a.m., 7-year-old twin brothers arrived at Mission Hospital in Asheville. Both had a fever, a cough, a rash, pink eye, and cold symptoms.

24 Feb 2026

Precision mRNA vaccine strategy shows early promise for improving TNBC relapse risk

An individualized neoantigen mRNA vaccine was tested in patients with early-stage triple-negative breast cancer and showed feasibility, safety, and strong T cell immune responses. Long-term follow-up suggested durable immune memory with encouraging relapse-free outcomes, though controlled trials are needed to confirm clinical benefit.

19 Feb 2026

COVID and flu vaccination rates during pregnancy remain low in Norway

A study of over 50,000 pregnant women in Norway during the 2023/24 influenza season found that only 29.9% were vaccinated against influenza and 12.1% against COVID-19 during pregnancy, remaining far below recommended targets.

19 Feb 2026

Study: Booster vaccines reduced severe COVID outcomes

Booster vaccines reduced the risk of COVID‑19–related hospitalisation and death, according to a new study of over 3 million adults who had the autumn 2022 vaccine in England.

18 Feb 2026

COVID vaccination during pregnancy linked to lower preeclampsia risk

A new multinational study from the INTERCOVID Consortium, including Ann & Robert H. Lurie Children's Hospital of Chicago, has found that COVID-19 vaccination during pregnancy, particularly when combined with a booster dose, significantly reduces the risk of preeclampsia, a serious and potentially life-threatening pregnancy complication.

18 Feb 2026

Fred Hutch scientists reach crucial milestone in blocking Epstein Barr virus

Fred Hutch Cancer Center scientists reached a crucial milestone in blocking Epstein Barr virus (EBV), a pathogen estimated to infect 95% of the global population that is linked to multiple types of cancer, neurodegenerative diseases and other chronic health conditions.

17 Feb 2026

OVACell project pioneers viral target immunotherapy for ovarian cancer

A small team at OVACell is fighting ovarian cancer with hidden viral sequences and advanced immunotherapies.

16 Feb 2026

Aptar Pharma’s intranasal solutions power CastleVax Phase II clinical trials for next-gen COVID-19 vaccine

In a significant step forward for mucosal immunity, Aptar Pharma has announced that its innovative nasal delivery systems are being utilized in CastleVax’s Phase II clinical trial for CVAX-01, an intranasal COVID-19 vaccine candidate.

From Hanson Wade Group - 4th Nasal Formulation & Delivery Summit 16 Feb 2026

Why lung cancer in never smokers is rising and how targeted detection could reduce deaths

Lung cancer in never smokers is an increasingly recognized global health issue with distinct biological drivers, environmental risk factors, and genetic susceptibilities. Improved risk modelling, targeted screening strategies, and preventive approaches are needed to enable earlier detection and reduce mortality in this growing patient group.

15 Feb 2026

Nasal COVID vaccine boost increases IgA responses linked to variant neutralisation

Intranasal boosting after prior intramuscular COVID vaccination induced strong mucosal IgA responses in a small human cohort. These antibodies showed markedly enhanced neutralising activity against Omicron variants and evidence of immune memory reprogramming toward mucosal protection.

15 Feb 2026

Antibody feedback reshapes B cell selection during immune response

A collaborative study published in Immunity from the Batista Lab and Liu Lab at the Ragon Institute, together with the Schief Lab at Scripps Research Institute, has uncovered a previously unrecognized mechanism that shapes how immune cells are selected during an immune response.

13 Feb 2026

Engineered Listeria boosts innate immunity against cancer

After nearly 40 years of research on how Listeria bacteria manipulate our cells and battle our immune system to cause listeriosis, Daniel Portnoy and his colleagues have discovered a way to turn the bacteria into a potent booster of the immune system - and a potential weapon against cancer.

13 Feb 2026

Novel antibody 007 targets the elusive HIV envelope epitope

HIV-1 can be neutralized by antibodies which bind to vulnerable structures on the virus surface. One such vulnerable site is the so-called V3 glycan site of the viral envelope protein.

13 Feb 2026