Sorbitol Research and Safety

Sorbitol is a naturally occurring sweetener synthetically extracted from glucose. Owing to its low calorific value, it is used in pharmaceutical products, sugar-free foods, and oral care products such as mouth fresheners and toothpastes. It is prescribed for use by diabetes patients as it has a lesser tendency to increase the sugar level in the blood.

Cup of sorbitol, a natural sweetener. Image Credit: Photosiber / Shutterstock
Cup of sorbitol, a natural sweetener. Image Credit: Photosiber / Shutterstock

Consumption of sorbitol gives a cooling sensation in the mouth with almost no aftertaste.  It helps to maintain the high quality of food products by retaining moisture, improving the texture, and acts as a crystallization modifier, a softening agent, and a viscosity controller. It is an important ingredient in confectionery items and food that need to be stored for some time. Sorbitol is a natural constituent of fruits such as apples and pears; dry fruits such as prunes and raisins; stoned fruits like apricots and peaches, and berries of the family of the Sorbus tree.

Sorbus aucuparia. Image Credit: Gucio_55 / Shutterstock
Sorbus aucuparia. Image Credit: Gucio_55 / Shutterstock

Research on Sorbitol

In 1985, a report by the European Union’s Scientific Committee on food stated that intake of above 50 g of sorbitol per day may result in diarrhea. It also stated that food containing greater than 10% of sorbitol may be harmful to health and can have a laxative effect. Polyols are alcohol sugars and sorbitol is a type of polyol. In Europe, polyols are banned in soft drinks because of their laxative effects.

In 2011, the European Food Safety Authority submitted a health report on polyols such as sorbitol and concluded that they could be used for improving dental health and for repairing teeth enamel. EFSA has no fixed safety margin for the daily intake of sorbitol.

Sorbitol was first used in the USA by the food industry in 1929. The Generally Recognized as Safe (GRAS) list of Food and Drug Administration (FDA) suggests a tolerance of 7% of sorbitol in foods. FDA studies have found no toxicity and determine the normal level of consumption of sorbitol to be 25 g daily in two doses. No carcinogenic effects were found in experiments on sorbitol. Animal studies involving rats injected with sorbitol showed no tumor incidences at the injection site.


Sorbitol has been declared safe for use by a number of scientific studies. The Joint Food and Agriculture Organization (JECFA) has categorized the acceptable daily intake (ADI) of sorbitol as “not specified,” which is actually the safest category for any food ingredient. There is no fixed upper margin for the intake level of sorbitol. However, FDA suggests that if the daily intake level of sorbitol exceeds 30 g per day, it may result in serious symptoms. People suffering from nausea, vomiting, or abdominal pain should avoid sweeteners like sorbitol, while pregnant and breast-feeding women should consult their physician before use.

Sorbitol is best used when stored at the normal atmospheric temperature (15°C to 30°C). Temperatures below this level may lead to thickening of sorbitol, and it should not be allowed to freeze.

Side Effects

The side effects of consumption of sorbitol are mild; the main health concern faced is gastrointestinal disturbances, as sorbitol does not get completely digested in the small intestine.

The small intestine absorbs sorbitol in small amounts, which are then converted to fructose. The presence of the excess amount of the remaining sorbitol may result in diarrhea. Excessive sorbitol usage may result in gastrointestinal complexities such as flatulence, bloating, cramping, and other abdominal discomforts. Sorbitol intake may cause serious problems in people who are highly sensitive to laxative effects caused by it.

Other side effects that may arise due to sorbitol usage are listed below:

  • In diabetic patients, it may lead to injury of blood vessels and nerves.
  • Damage to the eyes with formation of cataract and increased risk to the kidneys.
  • In rare cases, people may have skin allergies like itching and blisters on the surface of the skin.
  • Some people may suffer from anal and rectal itching.
  • Possibility of tarry stools.
  • Difficulty in breathing.
  • Excessive thirst.
  • Decrease in urine output.

Consultation with the physician is suggested if any of the above symptoms arise.

Effects on children


Generally, sorbitol does not lead to tooth decay. Starches and sugars in foods are split up by oral bacteria and these bacteria release acids. Such acids gradually destroy tooth enamel if they are not rinsed properly. Sorbitol and other sugar acids or polyols react against bacterial metabolism and hence there is no decay in the enamel.


Diabetic children are suggested to manage their blood lipids, glucose, and weight. As sorbitol is absorbed gradually and partially, the reaction of blood glucose and combined insulin is decreased. Also, the calorific value of sorbitol is two-thirds of normal sugar, so it is helpful in managing the body mass index among children.

However, the excess intake of this sweetener might have a negative impact on children.

Further Reading

Last Updated: Dec 28, 2022


The opinions expressed here are the views of the writer and do not necessarily reflect the views and opinions of News Medical.
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