What is Scabies?

Scabies is a common parasitic infection caused by the mite Sarcoptes scabiei variety hominis, arthropod of the order Acarina. Epidemics during wars, as well as famines and overcrowding, are responsible for an estimated 300 million cases of scabies worldwide every year.

Scabies: Signs, Symptoms, Causes, and Treatment | Merck Manual Consumer Version

From the time of the Greeks and Romans through the Middle Ages, the disease of scabies was also known as the “itch.” Roman physician Celsus is credited with describing its characteristic features and designating the term “scabies.” In 1687, Italian physician Giovanni Cosimo Bonomo discovered the parasitic etiology of the disease, making scabies one of the first illnesses with a known cause.

In modern medical literature, scabies refers to the various skin lesions produced by female mites, their eggs, and scybala, which is a medical term for hardened masses of feces, that are deposited in the epidermis, leading to a delayed-type hypersensitivity reaction. Hallmarks of the mite infestation include intense itching, papular rash, as well as emotional disturbance from the concept of arthropod infestation.

Mite biology and life cycle

The scabies mite represents an obligate ectoparasite that must live on the outside of a mammal host in order to survive. Although it is considered a single species (Sarcoptes scabiei), there are several physiological varieties or subspecies that are host-specific.

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The entire life cycle of the mite usually occurs in about 10 days for males and 14 days for females. After mating, the pregnant female crawls through the stratum corneum of the skin, tunneling her way with her strong mandibles. There, the female mite deposits two or three eggs, together with scybala, every day for several weeks.

These eggs hatch in approximately one week. In about three weeks, mature adults can be found. Adult mites have eight legs, which is a feature used to distinguish them from less mature larval forms that have six legs. The larval and nymph forms, as well as the males, live on the skin surface.

Transmission of the disease

Humans are the source of the infestation, with transmission usually occurring after prolonged and close skin-to-skin contact. In crusted or Norwegian scabies, which is a rare and severe form of the disease, the transmission may also occur as a result of exposure to infected clothing or bedding.

Once they find a new host, the mites can start to burrow within minutes. Presently, there is no published research on the minimum contact time required for the transfer of mites; therefore, any person in direct contact with an individual who has scabies is considered at risk.

Scabies mites are able to survive and remain capable of infestation for approximately 24 to 36 hours at room conditions, which is a temperature of approximately 21°C and 40%–80% relative humidity. additionally, these mites can also survive up to 19 days in a cool and humid environment. To identify a potential host, adult mites use odor and thermotaxis, which is a form of movement in response to changes in temperature.

This skin infestation often occurs in the form of cyclic epidemics. Significant associations with poverty, poor personal hygiene, overpopulation, and war-centric pandemics have been described. In fact, the disease is particularly rampant in overcrowded places without suitable sanitation such as nursing homes, schools, and prisons.

Scabies has a worldwide distribution and affects individuals of all ages with no specific gender predisposition. Additional public health significance of the disease is recognized when large numbers of individuals are affected. Outbreaks of scabies in such dimensions necessitate a special treatment strategy.


Further Reading

Last Updated: Apr 21, 2021

Dr. Tomislav Meštrović

Written by

Dr. Tomislav Meštrović

Dr. Tomislav Meštrović is a medical doctor (MD) with a Ph.D. in biomedical and health sciences, specialist in the field of clinical microbiology, and an Assistant Professor at Croatia's youngest university - University North. In addition to his interest in clinical, research and lecturing activities, his immense passion for medical writing and scientific communication goes back to his student days. He enjoys contributing back to the community. In his spare time, Tomislav is a movie buff and an avid traveler.


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