Life Science Articles

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High-performance Thin Layer Chromatography (HPTLC) in the Pharmaceutical Industry

High-performance Thin Layer Chromatography (HPTLC) is a robust and cost-effective separation technique employed in the development and analysis of new drugs.

17 Oct 2019

Human Cell Models of the Developing Cortex

Studying human brain development in vivo is difficult. Human cell models such as neurovascular organoids offer researchers unseen insights into the cortex.

17 Oct 2019

Improving Image Resolution Using Nanoparticles

Nanoparticles are small sized particles capable of penetrating vasculature and circulating the body.

15 Oct 2019

Using Phage Display for Antibody Discovery and Development

In phage-display, the gene encoding a bacteriophage protein is replaced with a gene encoding a novel protein. The technique can be used for antibody discovery.

16 Oct 2019

What Can We Learn from the Pan-Genome?

Some decades after the first ever genetic sequence of a living organism was shared, public databases contain several hundred complete bacterial genomes.

15 Oct 2019

Authenticating Complex Herbal Products using Liquid Chromatography

Scientists reviewed the current options for herbal product authentication by chromatographic techniques, to decide on a robust standardized technique.

8 Oct 2019

Confocal Versus Super-resolution Microscopy

Super-resolution microscopy refers to a collection of methods used to increase the resolution of light microscopy, whereas confocal microscopy uses a laser beam to increase the signal intensity from the sample.

11 Oct 2019

Revealing the Molecular Basis of Fragrances using Gas Chromatography

Researchers used multidimensional gas chromatography coupled to serial detection systems to provide deep insights into what makes a pleasant fragrance.

14 Oct 2019

What are Affimers?

Antibodies have been the most popular method for studying protein expression and function for the past decades, but have been dogged by lack of validation and the poor cost-effectiveness of constantly generating new antibodies.

25 Sep 2019

Sensing Oxidative Stress: The ROS-p53 Pathway

Oxidative stress occurs when there are high levels of reactive oxygen species (ROS) in the body, that are capable of damaging lipids, proteins, and DNA.

1 Oct 2019

Interfacial Protein Monolayers are Strong Enough to Hold a Cell

Scientists have shown that a protein monolayer deposited on a liquid-liquid interface between water and a perfluorocarbon solvent can hold hMSCs.

25 Sep 2019

Lipid Metabolism and the Gut Microbiota

This article describes examines the evidence for the role of the gut microbiota in lipid metabolism.

25 Sep 2019

Creating Hypoimmunogenic Induced Pluripotent Stem Cells (iPSCs)

iPSCs may be genetically modified into a hypoimmunogenic state to which the recipient’s immune system will respond less vigorously.

25 Sep 2019

Genetic Factors that Influence Bacterial Diversity in the Human Gut

“Microbiota” is a term used to describe the collection of microorganisms (bacteria, archaea, and eukaryotes) living in a particular environment. One such environment that hosts numerous microorganisms is the human gut.

24 Sep 2019

Aqueous Two-phase Systems: Pros and Cons

Aqueous two-phase systems, also known as ATPS, use the properties of the polymer surface and conformation of the materials to partition biomolecules.

25 Sep 2019

Malaria: A Force Shaping Blood Cell Evolution?

The existence of the DARC blood group in Africa suggests that the Plasmodium parasite is influencing the evolution of red blood cells in humans.

9 Sep 2019

Super-Resolution Microscopy vs. Electron Microscopy

Conventional light microscopy has its limits. Light, being a wave, is subject to diffraction which severely limits the size of structures one can resolve.

20 Sep 2019

Identifying Protein Biomarkers for COPD from Exhaled Air Condensate

In this case study, scientists identified novel protein biomarkers from exhaled air condensates from patients with COPD. The samples were analyzed by LC-MS.

9 Sep 2019