Life Science Articles

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What is Microbial Memory?

Complex organisms have the ability to remember, meaning that information about past experiences is memorized and can be recalled.

23 Aug 2019

The Ebola virus causes severe and often lethal infections. While an efficient treatment has not yet been found, it has been observed that Ebola-infection survivors develop antibodies against the virus, from which antibody-therapies could be derived.

29 Aug 2019

Measuring Cannabinoid Content in Seized Cannabis Samples

Researchers from the Institute of Forensic Medicine at the University of Bern have developed a new method for the forensic analysis and quality control of cannabis products.

29 Aug 2019

The Immunological Effects of Cannabinoids

The therapeutic effects of cannabinoids have been well-documented, but the effect of cannabinoids on the immune system is still not explored to a great extent. In a recent study, the researchers investigate the potential effects of the cannabinoids on inflammation and the mechanisms behind it.

23 Aug 2019

Crystal Structure of the Human Cannabinoid Receptor CB2

Phytocannabinoids in the form of Cannabis plant is widely consumed by humans. Two of the cannabinoid receptors, CB1 and CB2 are the key targets of this endocannabinoid system.

30 Aug 2019

Collagen Degradation Pathways in Humans

Collagen is a major protein which is found in connective tissues and the extracellular matrix (ECM). Helical in structure, at least 27 types of collagen have been identified in the human body, with Types I-IV being the most prevalent.

30 Aug 2019

HIV Suppression Using Adenovirus-Mediated Gene Therapy

In this case study, adenovirus-mediated gene therapy was shown to stimulate the production of broadly neutralizing antibodies that suppressed HIV levels

26 Aug 2019

Metabolomic Profiling of Ricin

Ricin is one of the most toxic substances known to science with an LD50 between 3 and 30 µg/kg in humans.

20 Aug 2019

Spin Labels in Electron Spin Resonance (ESR) Spectroscopy

In ESR, a spin label is added to the target site using cysteine substitution. The sulfhydryl group is then modified with a paramagnetic nitroxide reagent.

20 Aug 2019

2D NMR Spectroscopy: Fundamentals, Methods and Applications

2D NMR differs from 1D NMR by the acquisition stage being separated from the excitation stage. Each method of transfer of magnetization is described here.

20 Aug 2019

What is the Role of Vascular Endothelial Growth Factor?

Formation of new blood vessels can be divided into two processes – vasculogenesis and angiogenesis.

13 Aug 2019

Improving the Safety of Biotherapeutics: Tracing the Protease Inhibitor AEBSF with RPLC-UV

This article describes how RPLC-UV can be used to remove the common protease inhibitor, AEBSF, from antibody preparations for therapeutic applications.

18 Jul 2019

Detecting Cytokines using Intracellular Flow Cytometry

This article describes the validation of monesin in a 1993 study for use in intracellular flow cytometry for the detection of cytokines.

31 Jul 2019

Biosimilar Drugs: Overview and Industry Challenges

Biosimilar drugs are almost identical versions of a medical product or a drug that are produced by a different company to the parent company.

31 Jul 2019

Detecting Extracellular Vesicles in Urine Using a Robust Assay

This article describes how extracellular vesicles are detected and the development of a robust and reproducible assay that overcomes previous limitations.

31 Jul 2019

Using Flow Cytometry to Test Platelet Function in Neonates

In this case study, scientists used flow cytometry as a means of determining platelet function in neonates.

26 Aug 2019

Does the Microbiome Interact with the Human Endocrine System?

Whilst the effect of the microbiome on the digestive system has been studied over the past decade, the understanding of its effect on the endocrine system is less well understood.

13 Aug 2019

A Computational Tool for Column Selection in 2D Chromatography

Matching chromatography columns in 2D liquid chromatography largely depends on the experience of the experimenter. The computational technique eliminates this.

25 Jul 2019

Capturing Circulating Leukemia Cells for Analysis by Flow Cytometry

Researchers have developed a new methodology for the characterization of circulating leukemia cells, and other low-abundance cells, by flow cytometry.

25 Jul 2019

Plasmonics in Biology and Nanomedicine

Plasma is one of the fundamental states of matter that is generated when a neutral gas is heated or subjected to a strong electromagnetic field, both of which can result in the breaking of bonds and the stripping of electrons from atomic nuclei.

30 Aug 2019