Life Science Articles

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Applying Ultrasound to Cell Sorting

Researchers combined of a microfluidics-based single-cell stream with ultrasound acoustics to yield measurable ultrasound echoes of single cells.

18 Jul 2019

Metabolomic Profiling of an Ancient Herbal Medicine using UHPLC

Researchers have used UHPLC to elucidate the medicinal effects of Baccharis grisebachii, an ancient herbal medicine used in Argentina.

18 Jul 2019

Separating Flavinoids from Plasma Proteins using UHPLC-MS

Scientists have described a method to separate and characterize flavonoids by digesting plasma proteins with protease enzymes and performing UHPLC-MS.

18 Jul 2019

Induced Pluripotent Stem (iPS) Cells in Medicine and Research

Induced pluripotent stem cells have led to unprecedented opportunities in the pharmaceutical industry, but also in clinical and basic research

17 Jul 2019

How Important is Intronic Variation?

Intronic variation is highly common, but the majority of variants have no effect. This article describes cases where variants lead to disease.

15 Jul 2019

Pathway Analysis After Genome-Wide Association Studies

Pathway analysis is used to elucidate the impact of each genetic variant thought to be involved in a disease.

15 Jul 2019

Uses of CRISPR/Cas Biosensing Systems

Recently, the Cas9 enzyme has demonstrated potential as a biosensor, and various Cas effectors are now being applied to molecular diagnostics.

4 Jul 2019

Structure and Function of Proteoglycans

Proteoglycans are ubiquitous molecules that function as critical components of the extracellular matrix.

9 Jul 2019

Oligodendrocyte Progenitor Cells: Production and Uses

Oligodendrocytes are involved in the myelination of the axons, which in turn improves the function of the nerves and offers trophic support to longer axons.

9 Jul 2019

Induced Pluripotent Stem (iPS) Cells: Discovery, Advantages and CRISPR Cas9 Gene Editing

Induced pluripotent stem cells (iPS) are somatic cells that can be reprogrammed by expressing a combination of embryonic transcription factors.

17 Jul 2019

Acute Inflammation and the Leukocyte Adhesion Cascade

The movement of leukocytes from the circulatory system to the site of inflammation and subsequent attachment is an integral part of the innate immune system.

4 Jul 2019

Flow Cytometry Techniques used in Medicine and Research

This article describes the combination of flow cytometry with other techniques and the applications of these techniques in medicine and research.

28 Jun 2019

What is Stereology?

Stereology derives three-dimensional information from two-dimensional samples. It is often used to study or compare tissues and organs in the body.

1 Jul 2019

What is AFM-IR?

AFM-IR is an analytical technique used to characterize unknown substances on a nanoscale level by combining atomic force microscopy and infrared spectroscopy.

1 Jul 2019

Understanding Fluorochromes for Use in Flow Cytometry

Fluorescent markers are known as fluorochromes, a term that is used interchangeably with fluorophore. This article explains how fluorochromes work.

1 Jul 2019

Stem Cell Sources, Types, and Uses in Research

This article describes each type of stem cell, as well as some key landmark discoveries and the major applications of stem cells in medicine and research.

1 Jul 2019

Current and Future Applications of Rabbit Monoclonal Antibodies

In most clinical applications, the monoclonal antibodies (mAbs) used are usually of murine origin; however, the small spleen of the mouse is limited in its ability to generate antibodies.

1 Jul 2019

Protein Interaction Studies Using Microfluidics

A valuable application of microfluidics is the study of protein-protein interactions, providing essential insights into cell signaling and gene regulation.

1 Jul 2019