Life Science Articles

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Protein Crystallization Screening

High throughput crystallization techniques are frequently employed to generate the large numbers of high purity protein crystals needed for protein crystallography.

2 May 2019

Human Cell Line Authentication by STR Profiling

Short Tandem Repeat (STR) DNA profiling is one solution that has been proposed for the detection of cross-contamination and therefore authentication of human cell lines.

2 May 2019

Cell‐Cycle‐Dependent Regulation of Cell Adhesions

This article will describe recent studies which have expanded our knowledge of the role of focal adhesions in the cell cycle.

2 May 2019

Cytoophidia Assembly, Morphology & Function

Cytoophidia are filamentous structures present inside a cell that may have important roles in cell compartmentalization.

1 May 2019

Microseeding Explained

Microseeding is a method used in protein crystallography where small seed crystals can be used to induce the formation of larger crystals.

1 May 2019

What are Enhancer RNAs (eRNAs)?

Enhancer RNAs, or eRNAs, are short non-coding RNA molecules that are transcribed from the loci of enhancers.

24 Apr 2019

DNA Repair and Transcription: A Balancing Act

The potential for catastrophic consequence underpins the importance of selecting the correct decision between DNA repair and transcription.

24 Apr 2019

The Role of the CD38 Receptor in the Progression of HIV

The depletion of CD4+ T cells in HIV infection has long been correlated with the overexpression of the cell surface adhesion receptor protein, CD38.

24 Apr 2019

Targeted Proteomics: Benefits and Techniques

An emerging area in the field of proteomics is targeted proteomics, a technique concerned with the quantification of specific proteins.

24 Apr 2019

Sugar Analysis Using Chromatography

Many everyday food items contain high amounts of sugar, thus it is important to determine the types and concentration of sugar within these products, to inform consumers.

15 Apr 2019

Presenting GC-MS Results in a Publication

This article describes how to interpret and present GC-MS results in a publication, for all purposes.

24 Apr 2019

Nanoarrays vs Microarrays

Microarrays have provided unprecedented benefits for researchers for many years, but are now being superseded by nanoarrays, which have a higher sensitivity and simpler methodology.

15 Apr 2019

Hydrophilic Interaction Chromatography Advantages

Advantages of Hydrophilic Interaction Chromatography include: increased detection sensitivity, faster separation, and increased efficiency, compared to similar techniques.

15 Apr 2019

How to Store DNA

DNA is very sensitive and can easily degrade in certain conditions. This article describes how to store DNA for the short- and long-term.

15 Apr 2019

Biological Applications of GC-FPD

GC-FLP is widely used to detect samples containing sulfur and phosphorus, which can be found within living cells and structures such as tooth enamel.

15 Apr 2019

Analytical Techniques used in Human Biomonitoring

There has been a surge in the presence of pollutants and contaminants in the environment. Human biomonitoring is the study of such pollutants on the human body.

11 Apr 2019

Eukaryotic DNA Polymerase Enzymes

For all species, the process of DNA replication requires the use of multiple different DNA polymerase enzymes.

1 May 2019

DNA Polymerase Function

DNA replication is required to maintain the integrity of genomic information. This article describes the process of DNA replication, in a step-by-step manner.

11 Apr 2019

History of DNA Research: Scientific Pioneers & Their Discoveries

This article aims to provide a brief overview of the history of DNA research, leading up to Watson and Crick's discovery of the structure of DNA, and what came next.

1 May 2019