Life Science Articles

RSS

What is Single-Particle Cryo-Electron Microscopy?

Single particle cryo-EM helps to determine the three-dimensional structure of molecules and assemblies without crystallizing the samples.

3 Apr 2019

What is the Cellular Microenvironment?

The cellular microenvironment is defined as the local environment surrounding a cell, which contains physical and chemical signals that can influence cellular behavior.

3 Apr 2019

What are Adipocytes?

With obesity rates rising worldwide, there is a growing interest in understanding the formation and regulation of fat cells, or adipocytes, and how an increase in their number leads to disease.

1 Apr 2019

Using Small-Angle X-Ray Scattering (SAXS) to Study Metabolism

Small-Angle X-Ray Scattering (SAXS) is gaining importance in the field of metabolomics, for the assessment of metabolic state and related disorders.

1 Apr 2019

Using EC-MS to Study Neurotransmission

Apart from being used to understand the mechanism of various redox reactions, EC-MS can also be used to study the electrochemical changes involved in neurotransmission.

1 Apr 2019

Reflection Contrast Microscopy for Immunocytochemistry

As reflection contrast microscopy can generate high definition images at high penetration depths, it is commonly used in immunocytochemistry.

1 Apr 2019

Reflection Contrast Microscopy versus Brightfield Microscopy

This article summarizes the similarities and differences of brightfield microscopy and reflection contrast microscopy for different applications.

1 Apr 2019

Optimization Tips for Immunohistochemistry and Immunofluorescence

One important factor that affects immunohistochemistry and immunofluorescence is the choice of primary antibody.

1 Apr 2019

Non-Enzymatic RNA Primer Extension

This article describes the process of non-enzymatic RNA primer extension as a solution to the RNA world hypothesis.

1 Apr 2019

Microsphere-Assisted Microscopy: Advantages and Limitations

Recent studies have shown that transparent microspheres can generate an image with a super-resolution of 50 nanometers.

28 Mar 2019

Gold Nanoparticles for Raman Spectroscopy

Gold nanoparticles have found a useful application in the field of Raman spectroscopy, where they can increase Raman signal intensity.

28 Mar 2019

E-FRET Microscopy for Live Cell Imaging

This article compares E-FRET to FRET and describes the E-FRET formulae. E-FRET can be used to image live cells with reduced photobleaching.

28 Mar 2019

Detecting Aneuploidy Using Flow Cytometry

Aneuploidy is defined as a chromosomal aberration involving either an addition or deletion of chromosomes compared to the ‘normal' number of 46 chromosomes.

28 Mar 2019