Life Science Articles

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Why are Host Cell Proteins (HCPs) Dangerous in Biopharmaceuticals?

Host cell proteins are highly immunogenic, even when present at very low levels. This can cause a cytokine storm, and if untreated, death.

10 Apr 2019

The Differences Between White and Brown Adipose Tissue

White Adipose Tissue (WAT) stores excess energy as triglycerides, whereas Brown Adipose Tissue (BAT) dissipates stored energy as heat.

10 Apr 2019

What is Microdialysis?

Microdialysis is a valuable tool in neuroscience that can be used to investigate and learn about complex brain functions.

10 Apr 2019

What is E-FRET Imaging?

E-FRET is a more powerful version of FRET which accounts for weaknesses in the original FRET method.

10 Apr 2019

What is Electrochemical Mass Spectrometry (EC-MS)?

Electrochemical mass spectrometry (EC-MS) is a powerful and versatile technique used to induce and analyze a wide range of electrochemical processes and biological reactions.

11 Apr 2019

What is Connectomics?

Connectomics is the study of the brain’s structural and functional connections between cells, which is visualized as a connectome.

11 Apr 2019

ELISA versus Mass Spectrometry for the Detection of HCPs

Studies show that mass spectrometry is more sensitive to low abundance HCPs, which may be missed by ELISAs.

8 Apr 2019

EC-MS Applications in Neuroscience

Electrochemical mass spectrometry (EC-MS) is a technique that is used to characterize and analyze the effects of redox reactions on biomolecules, such as proteins peptides and nucleic acids.

8 Apr 2019

Controlling the Cellular Microenvironment in vitro

Using cell cultures, scientists are able to manipulate the cellular microenvironment in order to simulate physiological conditions in vivo.

8 Apr 2019

Biomedical Applications of Isotope-Dilution Liquid Chromatography

Isotope dilution chromatography can be used to analyze sugar levels in alcohol and human disease, as well as the nutritional value of supplements and activated carboxylates in cells and tissues.

8 Apr 2019

Best Chromatographic Techniques for Pesticide Analysis

As consumers become progressively more aware of what is in their food, pesticide analysis is becoming increasingly important.

5 Apr 2019

Benefits of Multiplex Immunoassays

There are two main ways of multiplexing an immunoassay; spatial separation or immobilizing antibodies onto different beads based on what they target.

5 Apr 2019

Background Noise in Western Blots

The key to a successful Western blot is achieving a signal to noise ratio allowing the detection of proteins while minimizing the background noise.

5 Apr 2019

Applications of CLARITY

One potent application of CLARITY lies in its ability to allow clear imaging of the human brain during pathogenesis or diseased state.

5 Apr 2019

Applications of Carbon Nanotubes (CNTs) in Regenerative Medicine

Regenerative medicine refers to the use of technology to directly or indirectly regenerate or grow and replace cells, tissues, or organs. Recently, CNTs have been used to support bone and tissue regeneration.

5 Apr 2019

Structural Motifs in Protein Biology

This article describes each type of structural motif in secondary protein structures, with examples.

5 Apr 2019

Single-Nucleus RNA Sequencing (sNuc-seq) Protocol

This article describes the laboratory protocol for Single Nucleus RNA Sequencing (sNuc-seq).

5 Apr 2019

Single-Nucleus RNA Sequencing (sNuc-seq) Applications

In earlier studies investigating RNA or DNA, all the cells of a population were pooled together to collect information.

3 Apr 2019

Secondary Transfer of DNA in Forensics

Secondary DNA transfer occurs when DNA is transferred to an object or person through an intermediate.

3 Apr 2019

Ribosome Structure

Ribosomes are highly complex, macromolecular structures that fulfil the vital role of protein synthesis in all living cells across species, from bacteria to eukaryotes.

3 Apr 2019