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Researchers discover backup protein quality control mechanism

Researchers from the Babraham Institute, UK, and the German Center for Neurodegenerative Diseases (DZNE) have identified a backup mechanism of protein quality control which prevents the toxic effects of protein aggregation in specific tissues when normal methods of molecular monitoring fail.

14 Sep 2023

JAX offers a fully validated, clinical whole genome sequencing test

Until quite recently, it was extremely difficult to detect the variants underlying many genetic disorders. In the absence of a defined cause, clinicians have little to guide treatment for those left without a genetic diagnosis, forcing patients and families to embark on a diagnostic odyssey with no guarantee of finding answers.

14 Sep 2023

Research opens up new directions to develop drugs for stopping cytokine storms

Constant exposure of cells to stressing agents, such as pathogens, may disturb an organism's normal functioning. To fight stress, cells have developed several coping mechanisms, including the inflammatory response.

14 Sep 2023

Research provides key insights into the molecular underpinnings of acute liver injury

In a study published in the journal of Genes & Diseases, a team of researchers from Chonnam National University and the Korea Research Institute of Bioscience and Biotechnology unveiled important insights into liver injury and its underlying molecular mechanisms.

14 Sep 2023

MIT study reveals why immunotherapy doesn't work for all cancer patients

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14 Sep 2023

Research suggests laminin could play role in slowing progression of breast tumors

Cells are capable of translating mechanical changes into biological responses. This process is known as mechanotransduction and plays a fundamental role in the progression of solid tumors, such as breast cancer.

14 Sep 2023

Oral SARS-CoV-2 vaccine shows promise in monkeys

A new paper in Biology Methods and Protocols, published by Oxford University Press, indicates that researchers studying SARS-CoV-2 may have developed new methods to administer vaccines orally, which would be both easier to administer and more effective at combatting illnesses.

13 Sep 2023

Rasip1 gene found to be intimately involved in the creation of blood cells

Blood has long been a symbol of life and health, so it may be surprising that some aspects of blood production, i.e., hematopoiesis, remain incompletely understood.

13 Sep 2023

New Omicron subvariant BA.2.86: A master of immune escape but not taking over yet

Researchers have isolated a new SARS-CoV-2 Omicron subvariant, BA.2.86, revealing its ability to escape neutralizing antibodies five-fold greater than its ancestor strain. Despite its enhanced immune evasion capabilities, BA.2.86 has not shown a significant difference in spread compared to other current variants.

13 Sep 2023

Dormant HIV reservoirs can spontaneously produce RNA and proteins, study finds

HIV anti-retroviral therapy is considered a treatment and not a cure because patients usually carry a reservoir of HIV-infected cells that can re-emerge if treatment stops.

13 Sep 2023

Interferon-gamma essential for lung-resident memory B cell development after influenza infection

During a bout of influenza, B cells interact with other immune cells and then take different paths to defend the body.

13 Sep 2023

Innovative technique provides unparalleled insight into autism pathology

Does the human brain have an Achilles heel that ultimately leads to Autism? With a revolutionizing novel system that combines brain organoid technology and intricate genetics, researchers can now comprehensively test the effect of multiple mutations in parallel and at a single-cell level within human brain organoids.

13 Sep 2023

Study helps explain why solid tumors often spread to the spine

The vertebral bones that form the spine are derived from a distinct type of stem cell that secretes a protein favoring tumor metastases, according to a study led by researchers at Weill Cornell Medicine.

13 Sep 2023

A family of weird proteins hijacks plants’ cellular plumbing

Many of the bacteria that ravage crops and threaten our food supply use a common strategy to cause disease: they inject a cocktail of harmful proteins directly into the plant's cells.

13 Sep 2023

Cerebellar inhibitory interneurons essential for fear memory, study finds

An LSU Health New Orleans research study led by Siqiong June Liu, PhD, Professor of Cell Biology and Anatomy, has found that cerebellar inhibitory interneurons are essential for fear memory, a type of emotional memory formation.

13 Sep 2023

UC Riverside study uncovers COVID's Achilles heel

New UC Riverside research has revealed COVID's Achilles heel - its dependence on key human proteins for its replication - which can be used to prevent the virus from making people sick.

13 Sep 2023

Microbiome composition influences severity of Legionnaires' disease

Pneumonia is an infection of the lung alveoli caused by bacteria, viruses or fungi. It is one of the leading causes of morbidity and mortality worldwide, representing a clinical and economic burden and a global public health problem.

13 Sep 2023

AfricaBP aims to foster grassroots knowledge exchange in biodiversity genomics and bioinformatics

Since its inception in 2021, the African BioGenome Project (AfricaBP), has made significant gains towards its ambitious goal of sequencing 100,000 endemic African species within the next 10 years.

13 Sep 2023

Genetics and diet shape insulin signaling in mice

Researchers have produced a comprehensive picture of insulin signalling in mice and suggest that it is shaped by entangled effects of genetics and diet.

13 Sep 2023

Kuano closes £1.8M seed funding round to validate quantum simulation platform for drug discovery

Kuano, a drug discovery company combining quantum mechanics with AI to design the next generation of medicines, today announced the close of its £1.8M seed funding round, led by Mercia Ventures, and including ACF Investors, Ascension Ventures, o2h Ventures, Meltwind Advisory LLP, and other Angel investors.

From Kuano Ltd. 13 Sep 2023

Life Science News

Researchers discover backup protein quality control mechanism

JAX offers a fully validated, clinical whole genome sequencing test

Research opens up new directions to develop drugs for stopping cytokine storms

Research provides key insights into the molecular underpinnings of acute liver injury

MIT study reveals why immunotherapy doesn't work for all cancer patients

Research suggests laminin could play role in slowing progression of breast tumors

Oral SARS-CoV-2 vaccine shows promise in monkeys

Rasip1 gene found to be intimately involved in the creation of blood cells

New Omicron subvariant BA.2.86: A master of immune escape but not taking over yet

Dormant HIV reservoirs can spontaneously produce RNA and proteins, study finds

Interferon-gamma essential for lung-resident memory B cell development after influenza infection

Innovative technique provides unparalleled insight into autism pathology

Study helps explain why solid tumors often spread to the spine

A family of weird proteins hijacks plants’ cellular plumbing

Cerebellar inhibitory interneurons essential for fear memory, study finds

UC Riverside study uncovers COVID's Achilles heel

Microbiome composition influences severity of Legionnaires' disease

AfricaBP aims to foster grassroots knowledge exchange in biodiversity genomics and bioinformatics

Genetics and diet shape insulin signaling in mice

Kuano closes £1.8M seed funding round to validate quantum simulation platform for drug discovery

Edoardo Fabini

Reducing polypharmacy through innovative drug formulation technologies

How innovation in dried blood spot testing is transforming neurological disease monitoring

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