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Popular genetic method is deeply flawed, study reveals

The most common analytical method within population genetics is deeply flawed, according to a new study from Lund University in Sweden.

30 Aug 2022

Italian study finds SARS-CoV-2 in clinical samples collected before December 2019

Researchers discuss the association of SARS-CoV-2 with morbilliform skin rash and confirms viral circulation in September 2019.

30 Aug 2022

In vivo imaging of α-synuclein aggregates in the brains of living patients with multiple system atrophy

α-synuclein is a neuronal protein involved in functions like vesicle trafficking and neurotransmitter release. It is typically found in abundance in a healthy brain.

30 Aug 2022

Vitamin D mediates crosstalk between COVID-19 and osteoporosis

Researchers identify and characterize the targets of Vit D on COVID-19 and osteoporosis.

30 Aug 2022

Study reveals a vital route through which fascin promotes cancer development

The study reveals an important route through which fascin promotes cancer development and provides insights into potential pathways that could block its action.

30 Aug 2022

Study reinforces the potential of Huntington’s treatments that target glia cells

Huntington's disease – a hereditary and fatal genetic disorder – has long been considered a neuronal disease due to the permanent loss of medium spiny motor neurons, the death of which over time is responsible for the clinical hallmarks of the disease: involuntary movements, problems with coordination, cognitive decline, depression, and psychosis.

30 Aug 2022

New labeling technique helps analyze the contents of exosomes from cells

Our cells are constantly communicating, and scientists have developed an efficient way to find out what messages they are sending in protein-packed biological suitcases called exosomes.

30 Aug 2022

Genetic screening before pregnancy detects the risk in 44% of couples

Are would-be parents carrying a genetic risk of serious illnesses that they could potentially pass on to their children? In the USA, doctors recommend that couples have genetic screening before trying to conceive.

30 Aug 2022

Researchers create first mouse model carrying a disease-associated mitochondrial mutation

Studying the role of mitochondria—the specialized structures within cells responsible for energy production—in metabolic diseases has been difficult because of a lack of animal models with the necessary mitochondrial mutations to observe these tiny organelles.

30 Aug 2022

Disrupting a virus’s genome packaging can halt replication, study finds

Like savvy international travelers, viruses know exactly how to pack. With the genetic instructions for the next generation folded just so, snuggled into a custom-made outer covering studded with cell-grabbing proteins, these tiny invaders quest for new digs on the reg.

30 Aug 2022

Study reveals a 'stealing' mechanism that contributes to antibody diversity

A few years ago, Professor Kathrin de la Rosa and her colleagues in the lab of the Swiss immunologist Antonio Lanzavecchia made an unusual discovery.

29 Aug 2022

Using organic metal nanohybrid structures to simultaneously identify multiple food poisoning bacteria

Osaka Metropolitan University scientists have developed a simple, rapid method to simultaneously identify multiple food poisoning bacteria, based on color differences in the scattered light by nanometer-scaled organic metal nanohybrid structures (NHs) that bind via antibodies to those bacteria.

29 Aug 2022

Intracellular bacteria protect their host against giant viruses, research shows

Amoebae receive surprising support in defense against viruses: The bacteria they are infected with prevent them from being destroyed by giant viruses.

29 Aug 2022

Viruses modify host cellular machinery to produce high amounts of viral progeny

The study, published in Nature Communications, shows a new mechanism whereby viruses modify cellular machinery so that it can better read the instructions in the genome of the invading virus.

29 Aug 2022

Single mutation in Kcnc3 gene causes learning deficits in mice

A single mutation in a gene, Kcnc3, which encodes a potassium channel in neurons, causes learning deficits in mice, UT Southwestern researchers report in a new study in PNAS.

29 Aug 2022

Researchers identify multiple genes and rare variants linked with Crohn's disease susceptibility

An international consortium of researchers has identified genetic variants in 10 genes that elevate a person's susceptibility to Crohn's disease, a form of inflammatory bowel disease.

29 Aug 2022

Study shows how the brain's tool for waste clearance malfunctions during bacterial meningitis

Bacterial meningitis is a life-threatening infectious disease of the brain that leaves many survivors with long-lasting neurological impairments.

29 Aug 2022

Microscopy technique enables visualization of unseen nanostructures within cells and tissues

Inside a living cell, proteins and other molecules are often tightly packed together. These dense clusters can be difficult to image because the fluorescent labels used to make them visible can't wedge themselves in between the molecules.

29 Aug 2022

Researchers receive $1.2 million Keck Foundation grant to find molecules for targeting the 'undruggable proteome'

The W.M. Keck Foundation has awarded a $1.2 million grant to medicinal chemistry and computational biology researchers at the University of Kansas and the University of Chicago focused on addressing a long-unresolved problem in biomedical research - finding molecules able to target the "undruggable proteome."

29 Aug 2022

Inactivation of particular protein complex associated with Parkinson's and anxiety disorders

Inactivation of a particular protein complex that plays a key role in keeping genes switched off leads to nerve cells not producing enough essential neurotransmitters.

29 Aug 2022

Life Science News

Popular genetic method is deeply flawed, study reveals

Italian study finds SARS-CoV-2 in clinical samples collected before December 2019

In vivo imaging of α-synuclein aggregates in the brains of living patients with multiple system atrophy

Vitamin D mediates crosstalk between COVID-19 and osteoporosis

Study reveals a vital route through which fascin promotes cancer development

Study reinforces the potential of Huntington’s treatments that target glia cells

New labeling technique helps analyze the contents of exosomes from cells

Genetic screening before pregnancy detects the risk in 44% of couples

Researchers create first mouse model carrying a disease-associated mitochondrial mutation

Disrupting a virus’s genome packaging can halt replication, study finds

Study reveals a 'stealing' mechanism that contributes to antibody diversity

Using organic metal nanohybrid structures to simultaneously identify multiple food poisoning bacteria

Intracellular bacteria protect their host against giant viruses, research shows

Viruses modify host cellular machinery to produce high amounts of viral progeny

Single mutation in Kcnc3 gene causes learning deficits in mice

Researchers identify multiple genes and rare variants linked with Crohn's disease susceptibility

Study shows how the brain's tool for waste clearance malfunctions during bacterial meningitis

Microscopy technique enables visualization of unseen nanostructures within cells and tissues

Researchers receive $1.2 million Keck Foundation grant to find molecules for targeting the 'undruggable proteome'

Inactivation of particular protein complex associated with Parkinson's and anxiety disorders

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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