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New technique can accurately detect viruses in tumors from clinical next-generation sequencing

Researchers have developed a method to accurately detect viruses from clinical next-generation sequencing and describe novel associations between specific tumors and viruses that warrant further investigation.

5 May 2022

New method improves polygenic prediction of disease risk across diverse populations

Polygenic risk scores (PRS) are promising tools for predicting disease risk, but current versions have built-in bias that can affect their accuracy in some populations and result in health disparities.

5 May 2022

Viral microRNA acts as a master regulator to induce the reactivation of dormant herpesviruses

Dormant herpesviruses induce their reactivation via a previously unknown cellular mechanism mediated by a viral microRNA. Würzburg researchers show this in the journal "Nature".

5 May 2022

SARS-CoV-2 develops partial resistance to the antiviral drug remdesivir in cell culture

The virus that causes COVID-19 can develop partial resistance to the antiviral drug remdesivir during infection of cultured cells in the laboratory by more than one mechanism.

5 May 2022

Fecal microbiota transplant can reverse hallmarks of aging in mice

In the search for eternal youth, poo transplants may seem like an unlikely way to reverse the aging process.

5 May 2022

Win 1 of 10 INTEGRA VOYAGER pipette kits!

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From INTEGRA Biosciences 5 May 2022

New model can predict drug-drug interactions based on drug-induced gene expression signatures

Prescriptions for multiple drugs, or polypharmacy, is often recommended for the treatment of complex diseases.

4 May 2022

Benefits of endurance exercise in primary mitochondrial disease depend on the underlying mutation

Mitochondria serve as the main source of energy production in our cells, and endurance exercise is generally known to improve the function of mitochondria.

4 May 2022

New insights into the cellular and molecular mechanisms of absence seizures

Bochum researchers have gained new insights into the cellular and molecular mechanisms of absence seizures and potential therapy options.

4 May 2022

New Machine Learning model draws a map of proteins with special properties

The biotech industry is constantly searching for the perfect mutation, where properties from different proteins are synthetically combined to achieve a desired effect.

4 May 2022

Researchers overcome a major hurdle to reverse hearing loss due to aging

Hearing loss due to aging, noise and certain cancer therapy drugs and antibiotics has been irreversible because scientists have not been able to reprogram existing cells to develop into the outer and inner ear sensory cells -- essential for hearing – once they die.

4 May 2022

Experts develop new method to control gene expression using electrical signals

Researchers have created an improved method for turning genes on and off using electrical signals.

4 May 2022

Improved viral RNA extraction from nasal and throat swab samples

The Chromatrap® Homogeniser Spin Column from Porvair Sciences maximises the yield and quality of viral RNA extracted from nasal and throat swab samples.

From Porvair Sciences Limited 4 May 2022

Researchers create models to study brain metastases that recapitulate the disease

The spreading of different types of cancer cells to the brain, forming brain metastases, is the main cause of morbidity and mortality associated to cancer. Now, a new study led by Cláudia C. Faria, principal investigator in the group of João Taborda Barata at the Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal) and neurosurgeon at the Hospital Santa Maria (HSM, CHULN, Portugal), and published today in the scientific journal Cell Reports Medicine* created a library of models to study brain metastases that recapitulate the disease in humans. These models can be a relevant tool to understand the disease and discover new therapeutical approaches tailormade to each patient.

4 May 2022

Study offers a path to closing the knowledge gap about differences in breast cancer genes

Too many women are getting unnecessary mastectomies and other invasive procedures because of a knowledge gap about differences in cancer genes. A new study offers a path to closing the gap.

4 May 2022

Researchers use electricity to design tool that may help create pharmaceutical compounds

What do gunpowder, penicillin and Teflon all have in common? They were inventions that took the world by storm, but they were all created by complete accident.

4 May 2022

Injectable hydrogels for single-dose COVID-19 vaccination

Several coronavirus disease 2019 (COVID-19) vaccines require multiple doses for long-lasting immunity. However, a new study published in the journal Biomacromolecules has developed a promising single-dose vaccine platform using an injectable hydrogel containing an epitope-labeled plant virus, Cowpea mosaic virus (CPMV).

4 May 2022

Life Science News

New technique can accurately detect viruses in tumors from clinical next-generation sequencing

New method improves polygenic prediction of disease risk across diverse populations

Viral microRNA acts as a master regulator to induce the reactivation of dormant herpesviruses

SARS-CoV-2 develops partial resistance to the antiviral drug remdesivir in cell culture

Fecal microbiota transplant can reverse hallmarks of aging in mice

Win 1 of 10 INTEGRA VOYAGER pipette kits!

New model can predict drug-drug interactions based on drug-induced gene expression signatures

Benefits of endurance exercise in primary mitochondrial disease depend on the underlying mutation

New insights into the cellular and molecular mechanisms of absence seizures

New Machine Learning model draws a map of proteins with special properties

Researchers overcome a major hurdle to reverse hearing loss due to aging

Experts develop new method to control gene expression using electrical signals

Improved viral RNA extraction from nasal and throat swab samples

Researchers create models to study brain metastases that recapitulate the disease

Study offers a path to closing the knowledge gap about differences in breast cancer genes

Researchers use electricity to design tool that may help create pharmaceutical compounds

Injectable hydrogels for single-dose COVID-19 vaccination

Proximity labeling to identify high-confidence SARS-CoV-2 interactors

Using silk proteins for tendon repair

New method enables the structural analysis of RNA molecules

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

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