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Research opens the door to novel therapies for cancer induced by hedgehog signaling pathway

A research led by Hong Kong University of Science and Technology has revealed a novel mechanism that regulates secretion of sonic hedgehog (Shh), a key signaling molecular that plays an important role in cancer progression, in mammals, opening the door to novel therapeutic strategies for cancer induced by the hedgehog signaling pathway.

9 May 2022

COVID-19 mortality among elderly may be due to genetically predetermined limit on the immune system

Your immune system's ability to combat COVID-19, like any infection, largely depends on its ability to replicate the immune cells effective at destroying the SARS-CoV-2 virus that causes the disease.

9 May 2022

Inversions in the human genome found to be more common than previously thought

Researchers at EMBL Heidelberg found that inversions in the human genome are more common than previously thought, which impacts our understanding of certain genetic diseases.

6 May 2022

Researchers confirm the existence of 36-mer cellulose synthase supercomplex in cotton fiber

About 180 billion tons of celluloses are produced by the world's vegetation annually, making this polysaccharide the most abundant biological macromolecule on earth.

6 May 2022

Single-cell RNA sequencing reveals characteristics of myeloid immune cells in coronary plaque

Through single-cell RNA sequencing, a research group has successfully illuminated the characteristics of Myeloid immune cells in coronary plaque, which causes acute coronary syndrome (this term includes conditions such as unstable angina and acute myocardial infarction (heart attack)).

6 May 2022

Mitosis in moss plants could be far more similar to animal cell division than previously thought

For a new plant to grow from a seed, cells need to divide numerous times. Daughter cells can each take on different tasks and sometimes vary in size. How plants determine the plane of cell division in this process, known as mitosis, is being researched by Prof. Dr. Ralf Reski and Dr. Elena Kozgunova from the University of Freiburg in a joint effort with Prof. Dr. Gohta Goshima from Nagoya University.

6 May 2022

Study confirms accuracy of new generation GastroPanel® test

A clinical validation study conducted at Oulu University Hospital (OUH) has confirmed the high accuracy of BIOHIT Oyj’s new generation GastroPanel® test for the diagnosis of atrophic gastritis (AG) and Helicobacter pylori (Hp) infection in patients referred for gastroscopy.

From BIOHIT HealthCare Ltd 6 May 2022

Applying a form of AI to sift through large amounts of biological data

Researchers at the University of Missouri are applying a form of artificial intelligence (AI) - previously used to analyze how National Basketball Association (NBA) players move their bodies - to now help scientists develop new drug therapies for medical treatments targeting cancers and other diseases.

6 May 2022

Marine bioactive compounds against SARS-CoV-2

A new review paper published in the journal Environmental Science and Pollution Research aimed to determine the possibilities of using biologically active compounds derived from various chemical classes of marine organisms against SARS-CoV-2 infection at various stages of the life cycle of the virus.

6 May 2022

Stem cell therapy prevents type 1 diabetes induced by anti-cancer drugs

Immune checkpoint inhibitors are widely used to treat a variety of cancers; however, one serious side effect is the onset of type 1 diabetes.

6 May 2022

miRNAs associated with varying clinical presentations of SARS-CoV-2

A recent article published in the journal iSCIENCE demonstrated different micro ribonucleic acids (miRNAs) linked with various presentations of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

5 May 2022

New technique can accurately detect viruses in tumors from clinical next-generation sequencing

Researchers have developed a method to accurately detect viruses from clinical next-generation sequencing and describe novel associations between specific tumors and viruses that warrant further investigation.

5 May 2022

New method improves polygenic prediction of disease risk across diverse populations

Polygenic risk scores (PRS) are promising tools for predicting disease risk, but current versions have built-in bias that can affect their accuracy in some populations and result in health disparities.

5 May 2022

Viral microRNA acts as a master regulator to induce the reactivation of dormant herpesviruses

Dormant herpesviruses induce their reactivation via a previously unknown cellular mechanism mediated by a viral microRNA. Würzburg researchers show this in the journal "Nature".

5 May 2022

SARS-CoV-2 develops partial resistance to the antiviral drug remdesivir in cell culture

The virus that causes COVID-19 can develop partial resistance to the antiviral drug remdesivir during infection of cultured cells in the laboratory by more than one mechanism.

5 May 2022

Fecal microbiota transplant can reverse hallmarks of aging in mice

In the search for eternal youth, poo transplants may seem like an unlikely way to reverse the aging process.

5 May 2022

Win 1 of 10 INTEGRA VOYAGER pipette kits!

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From INTEGRA Biosciences 5 May 2022

New model can predict drug-drug interactions based on drug-induced gene expression signatures

Prescriptions for multiple drugs, or polypharmacy, is often recommended for the treatment of complex diseases.

4 May 2022

Benefits of endurance exercise in primary mitochondrial disease depend on the underlying mutation

Mitochondria serve as the main source of energy production in our cells, and endurance exercise is generally known to improve the function of mitochondria.

4 May 2022

New insights into the cellular and molecular mechanisms of absence seizures

Bochum researchers have gained new insights into the cellular and molecular mechanisms of absence seizures and potential therapy options.

4 May 2022

Life Science News

Research opens the door to novel therapies for cancer induced by hedgehog signaling pathway

COVID-19 mortality among elderly may be due to genetically predetermined limit on the immune system

Inversions in the human genome found to be more common than previously thought

Researchers confirm the existence of 36-mer cellulose synthase supercomplex in cotton fiber

Single-cell RNA sequencing reveals characteristics of myeloid immune cells in coronary plaque

Mitosis in moss plants could be far more similar to animal cell division than previously thought

Study confirms accuracy of new generation GastroPanel® test

Applying a form of AI to sift through large amounts of biological data

Marine bioactive compounds against SARS-CoV-2

Stem cell therapy prevents type 1 diabetes induced by anti-cancer drugs

miRNAs associated with varying clinical presentations of SARS-CoV-2

New technique can accurately detect viruses in tumors from clinical next-generation sequencing

New method improves polygenic prediction of disease risk across diverse populations

Viral microRNA acts as a master regulator to induce the reactivation of dormant herpesviruses

SARS-CoV-2 develops partial resistance to the antiviral drug remdesivir in cell culture

Fecal microbiota transplant can reverse hallmarks of aging in mice

Win 1 of 10 INTEGRA VOYAGER pipette kits!

New model can predict drug-drug interactions based on drug-induced gene expression signatures

Benefits of endurance exercise in primary mitochondrial disease depend on the underlying mutation

New insights into the cellular and molecular mechanisms of absence seizures

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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