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Scientists create a biobank of 87 triple-negative breast cancer organoids

It's the cancer version of "mini me." Cold Spring Harbor Laboratory (CSHL) Professor David Spector, among others, has developed organoids, which are miniature, three-dimensional copies of cancers. Organoids can be derived from cancer or healthy cells.

30 Mar 2022

Study identifies 10 new genetic regions linked with Brugada syndrome

A recent study published in Nature Genetics identified 10 new genetic regions associated with Brugada syndrome, a cardiac arrhythmia disorder associated with sudden death in young adults.

30 Mar 2022

Preclinical investigation of intranasal adjuvanted COVID-19 vaccine

A new study reported systemic and mucosal immunity against SARS-CoV-2 via intranasal delivery of a vaccine containing recombinant SARS-CoV-2 antigens, nucleocapsid, and spike subunit.

30 Mar 2022

ProteoGenix launches new XtenCHOTM Transient CHO Expression System to improve biologics development

ProteoGenix, a contract research organization specialized in biologics discovery and bioproduction, announces the launch of its XtenCHOTM Transient Expression System.

From ProteoGenix 30 Mar 2022

Bruker introduces Ultima Investigator Plus — Multiphoton microscope for tissue imaging

Bruker today announced the release of the Ultima Investigator Plus, the newest modular platform addition to the industry-leading Ultima line of multiphoton microscopes for deep tissue fluorescence imaging.

From Bruker Nano Surfaces and Metrology 30 Mar 2022

Aivia 10.5 offers up to 74% time saving with AI-powered neuron analysis

Aivia 10.5 offers up to 74% time saving with AI-powered neuron analysis. Aivia software update from Leica Microsystems offers improved AI image analysis capabilities

From Leica Microsystems GmbH 30 Mar 2022

Furin inhibitors as potential therapies to combat SARS-CoV-2 and other diseases

Furin inhibitors as potential therapeutics for treating COVID-19 and other diseases, wherein furin is integral for their pathogenicity and progression.

29 Mar 2022

New tissue-clearing method could speed the study of many disease-related biological processes

Scientists at Scripps Research have unveiled a new tissue-clearing method for rendering large biological samples transparent.

29 Mar 2022

Researchers report progress en route to developing a hypoallergenic cat

Researchers at InBio (formerly Indoor Biotechnologies), a biotech company in Virginia, report progress en route to developing a hypoallergenic cat – or at least treating patients with allergies to the domestic cat – in a new article published online in The CRISPR Journal.

29 Mar 2022

Researchers discover a four-protein complex that may play key role in generating ribosomes

UT Southwestern researchers have identified a four-protein complex that appears to play a key role in generating ribosomes – organelles that serve as protein factories for cells – as well as a surprising part in neurodevelopmental disorders.

29 Mar 2022

Study finds less diverse circulating antibodies in aging killifish

As we age, our immune system works less well. We become more susceptible to infections and vaccinations no longer work as effectively.

29 Mar 2022

Trigeminal ganglia cell atlas implicates several cell types in migraine

Headaches such as migraine are among the leading causes of morbidity worldwide, but most treatments provide only partial relief.

29 Mar 2022

Utilizing AI to Accelerate the Field of High Content Analysis

In this interview, we speak to Araceli Biosciences about their latest product the Araceli Endeavor, and how its revolutionizing the field of high content screening.

From Society for Laboratory Automation and Screening (SLAS) 29 Mar 2022

Study reveals a deeper level of cellular heterogeneity within fallopian tubes

The fallopian tube is the site of fertilization, where once a month for the duration of a female's post-pubescent, pre-menopausal life, an egg is moved from the ovary, ready for fertilization by a sperm cell.

29 Mar 2022

Strand displacement mechanism in RNA appears to switch genetic expression from “on” to “off”

Similar to a light switch, RNA switches (called riboswitches) determine which genes turn "on" and "off." Although this may seem like a simple process, the inner workings of these switches have confounded biologists for decades.

29 Mar 2022

Japanese researchers discover new mechanisms of action by extracellular vesicles in lymphoma

Japanese collaborative research teams have discovered new mechanisms of action by extracellular vesicles (EV) for the development and malignant progression of lymphomas.

28 Mar 2022

Study shows how cells use octopus-like tentacles to move around the body

With help from the best tweezers in the world a team of researchers from the University of Copenhagen has shed new light on a fundamental mechanism in all living cells that helps them explore their surroundings and even invade tissue.

28 Mar 2022

CDK6: a potential drug target for severe COVID-19

Researchers identify a methodology and workflow to repurpose drugs against the cyclin-dependent kinase 6 target gene of SARS-CoV-2.

27 Mar 2022

Biologists discover gene deletion behind abnormality in blood cancer cells

The mystery is being unraveled of why the control centers, or nuclei, of certain blood cancer cells have a distinctly odd shape.

27 Mar 2022

Researchers discover new pathway for DNA transfer in tumor microenvironment

University of Notre Dame researchers have discovered another way tumor cells transfer genetic material to other cells in their microenvironment, causing cancer to spread.

25 Mar 2022