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A theoretical model may help better understand how blood circulates in the brain

Research carried out by the Universidad Carlos III de Madrid (UC3M) may help us better understand oscillations in blood flow that occur in the cerebrovascular network, thanks to a theoretical model that allows the flow and accumulation of fluid (in this case, blood) to be taken into account.

4 Feb 2022

Researchers find a way to interfere with the energy pathway that promotes liver cancer spread

The World Health Organization projects that starting in 2030, over a million people will die each year from liver cancer.

4 Feb 2022

Wistar researchers takes a promising step in the direction of developing HIV vaccine

Nearly four decades after its discovery, HIV has killed 36.3 million people, with no vaccine in sight. However, a new study by researchers at The Wistar Institute, an international biomedical research leader in cancer, immunology, infectious disease, and vaccine development, takes a promising step in the direction of developing an HIV vaccine.

4 Feb 2022

Molecular simulations provide insight into SARS-CoV-2 variant RBD interactions with ACE2 and mAbs

Researchers aimed to understand the relationship between the SARS-CoV-2 receptor-binding domain and both human receptors and therapeutic targets.

3 Feb 2022

Evaluating effects of D614G and P681R/H mutations on SARS-CoV-2 VOCs

Researchers evaluate how the D614G and P681H mutations alter the attributes of SARS-CoV-2 VOCs.

3 Feb 2022

SARS-CoV-2 human challenge study offers novel insights into viral kinetics

Researchers discuss the results of a human challenge study to provide novel insights into the early dynamics of SARS-CoV-2 infection.

3 Feb 2022

Scientists identify genome regions linked to migraine risk

An international consortium of leading migraine scientists identified more than 120 regions of the genome that are connected to risk of migraine.

3 Feb 2022

Study identifies a genetic mutation linked to high risk of lethal childhood leukemia

A genetic variant changing just one base pair of nucleotides greatly increases risk of a high-risk subtype of childhood acute lymphoblastic leukemia (ALL), according to a Northwestern Medicine study published in Nature Genetics.

3 Feb 2022

New method may be effective at quantifying DNA adenine methylation in complex organisms

For decades, a small group of cutting-edge medical researchers have been studying a biochemical, DNA tagging system, which switches genes on or off. Many have studied it in bacteria and now some have seen signs of it in, plants, flies, and even human brain tumors.

3 Feb 2022

CRISPRa method helps discover genes that play a role in immune cell biology

CRISPR genome editing has served as a powerful tool for deleting or altering DNA sequences and studying the resulting effect.

3 Feb 2022

Spice could play a key role in reducing salt intake among seniors

Montero, M.L., et al. (2022) Saltiness perception in white sauce formulations as tested in older adults. Food Quality and Preference. doi.org/10.1016/j.foodqual.2022.104529.

3 Feb 2022

Sample management of Covid-19 Cryobox tube racks

Ziath reports on the widespread adoption of its DataPaq™ Cube rack reader in Covid-19 testing labs for tracking of sample tubes cryogenically stored in cryoboxes.

3 Feb 2022

Nanoparticle vaccine effective against eight SARS-CoV-2 variants in non-human primates

Researchers demonstrate that SARS-CoV-2 RBD-based nanoparticle vaccine induces neutralizing antibodies against SARS-CoV-2 variants.

2 Feb 2022

Genome study reveals unexpected heterogeneity of human ribosomal RNA genes

A genome study undertaken by Johns Hopkins Kimmel Cancer Center researchers to look for variants in a gene considered a fundamental building block for microscopic structures that synthesize proteins took a surprising twist.

2 Feb 2022

Study offers unprecedented insight into the mechanism of action of topo VI enzyme

The function of an enzyme, critical to most forms of life, has been revealed.

2 Feb 2022

Study reveals a direct correlation between fat browning and consumption of flavan 3-ols

In cold conditions, brown adipose tissue (BAT) or brown fat generates heat to keep the body warm. Compared with white adipose tissue, BAT has more mitochondria - subcellular organelles associated with energy production - which allows it to burn calories and produce heat by activating the mitochondrial uncoupling protein 1 (Ucp-1).

2 Feb 2022

Three different autism risk genes found to have similar effects on brain development

Autism spectrum disorder has been associated with hundreds of different genes, but how these distinct genetic mutations converge on a similar pathology in patients has remained a mystery.

2 Feb 2022

UCLA researchers develop first human genomic transgenic mouse model of Huntington's disease

Researchers at the Jane and Terry Semel Institute for Neuroscience and Human Behavior at UCLA and the David Geffen School of Medicine at UCLA have developed a new mouse model of Huntington's disease that recapitulates more Huntington's disease-like characteristics than earlier models.

2 Feb 2022

Study discovers how long-term memory T cells are formed after SARS-CoV-2 exposure

Exposure to SARS-CoV-2 by infection or vaccination generates immune cells that provide long-term immunity. These long-lived memory T cells play a key role in preventing severe cases of Covid-19. Researchers at the University of Zurich have now discovered how these memory T cells form.

2 Feb 2022

Researchers elucidate first 3D structure of regulator protein complex

Proteins are indispensable components in living organisms. They are not only "building material" for the body – they also make molecular communication between cells possible, they are needed for nerve impulses to occur, and they control chemical reactions.

2 Feb 2022

Life Science News

A theoretical model may help better understand how blood circulates in the brain

Researchers find a way to interfere with the energy pathway that promotes liver cancer spread

Wistar researchers takes a promising step in the direction of developing HIV vaccine

Molecular simulations provide insight into SARS-CoV-2 variant RBD interactions with ACE2 and mAbs

Evaluating effects of D614G and P681R/H mutations on SARS-CoV-2 VOCs

SARS-CoV-2 human challenge study offers novel insights into viral kinetics

Scientists identify genome regions linked to migraine risk

Study identifies a genetic mutation linked to high risk of lethal childhood leukemia

New method may be effective at quantifying DNA adenine methylation in complex organisms

CRISPRa method helps discover genes that play a role in immune cell biology

Spice could play a key role in reducing salt intake among seniors

Sample management of Covid-19 Cryobox tube racks

Nanoparticle vaccine effective against eight SARS-CoV-2 variants in non-human primates

Genome study reveals unexpected heterogeneity of human ribosomal RNA genes

Study offers unprecedented insight into the mechanism of action of topo VI enzyme

Study reveals a direct correlation between fat browning and consumption of flavan 3-ols

Three different autism risk genes found to have similar effects on brain development

UCLA researchers develop first human genomic transgenic mouse model of Huntington's disease

Study discovers how long-term memory T cells are formed after SARS-CoV-2 exposure

Researchers elucidate first 3D structure of regulator protein complex

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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