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Immune cells in cerebrospinal fluid could be novel biomarkers of response to immune-based therapies

Results from a study led by Joan Seoane, Director of Preclinical and Translational Research co-program at VHIO and ICREA Professor, show that immune cells accessing cerebrospinal fluid faithfully recapitulate the characteristics of cells identified in brain metastasis, and could therefore constitute novel biomarkers of response to immune-based therapies.

8 Mar 2021

Scientists optimize wastewater disinfection process to minimize spread of antibiotic resistance

Antibiotic-resistant bacteria have become a global threat today, owing in part to the efficiency with which resistance spreads among them. Some of this spread happens in waterbodies—and our wastewater systems are no exception.

8 Mar 2021

Review helps understand the mechanisms of R-CHOP resistance in diffuse large B-cell lymphoma

Diffuse large B-cell lymphoma (DLBCL) is an aggressive cancer of lymphocytes, and a large proportion of patients are either unresponsive or develop resistance towards R-CHOP—the standard treatment regimen.

8 Mar 2021

Study reveals physical phenomena relied by oocytes to grow big

Egg cells are by far the largest cells produced by most organisms. In humans, they are several times larger than a typical body cell and about 10,000 times larger than sperm cells.

8 Mar 2021

Researchers call for ecosystem services that are directly linked to species diversity

In the future, assessments of ecosystems in terms of their contributions to people should take greater account of the importance of species diversity.

8 Mar 2021

New, efficient method facilitates antibody development

In recent years, therapeutic antibodies have transformed the treatment of cancer and autoimmune diseases.

5 Mar 2021

Researchers identify human BCAS3 and C16orf70 as novel autophagic proteins

Autophagy is an intracellular degradation process of cytosolic materials and damaged organelles. Researchers at Ubiquitin Project of TMIMS have been studying the molecular mechanism of mitophagy, the selective autophagy process to eliminate damaged mitochondria.

5 Mar 2021

Aptamer Group Extends Collaboration With Leading Biopharmaceutical Company to Explore Next-Generation Drug Delivery Approaches

Aptamer Group, the developer of Optimer™ reagents and therapeutics, today announced the extension of their current agreement with AstraZeneca, a global biopharmaceutical company. Image credit: Shutterstock.com/Billion Photos

From Aptamer Group 5 Mar 2021

A small sensor can be used for rapid detection of RNA and DNA

In less than a second, a small sensor used in brain chemistry research can detect the key molecules that provide the genetic instructions for life, RNA, and DNA, a new study from American University shows

5 Mar 2021

New COVID-19 variants can evade antibodies that work against original form of the virus

New research at Washington University School of Medicine in St. Louis indicates that three new, fast-spreading variants of the virus that cause COVID-19 can evade antibodies that work against the original form of the virus that sparked the pandemic.

5 Mar 2021

Study suggests revisiting 14-day limit on human embryo in a dish

An international team of bioethicists and scientists, led by a researcher at Case Western Reserve University, contends it may be justified to go beyond the standing 14-day limit that restricts how long researchers can study human embryos in a dish.

5 Mar 2021

Study demonstrates the impact of 'reverse antibiotic' on gram-negative bacteria

Scientists from Skoltech and MSU have investigated antibiotic nybomycin that could prove effective against bacteria resistant to other antibiotics. Their research was published in the journal Antimicrobial Agents and Chemotherapy.

5 Mar 2021

SARS-CoV-2 can evade immune response by T-killer cells through mutations

The body's immune response plays a crucial role in the course of a SARS-CoV-2 infection. In addition to antibodies, the so-called T-killer cells, are also responsible for detecting viruses in the body and eliminating them.

5 Mar 2021

Insight into how plants sense zinc could help cultivate more nutritious crops

Over 2 billion people worldwide are malnourished due to zinc deficiency. Led by the University of Copenhagen, an international team of researchers has discovered how plants sense zinc and use this knowledge to enhance plant zinc uptake, leading to an increase in seed zinc content by 50 percent.

5 Mar 2021

Pancreatitis drug blocks SARS-CoV-2 activators in the upper respiratory tract

Pancreatitis drug Camostat inhibits new SARS-CoV-2 activators identified in the upper respiratory tract. There are no therapeutics available that have been developed for COVID-19 treatment.

5 Mar 2021

Researchers decipher how interspecies interactions arise, evolve and are maintained

Interspecies interactions are the foundation of ecosystems, from soil to ocean to the human gut. Among the many different types of interactions, syntrophy is a particularly important and mutually beneficial interspecies interaction where one partner provides a chemical or nutrient that is consumed by the other in exchange for a reward.

5 Mar 2021

Proteomics analysis from aggressive human cancers can help identify potential therapeutic targets

Researchers at Baylor College of Medicine show that analysis of the proteomics, or all the protein data, from aggressive human cancers is a useful approach to identify potential novel therapeutic targets.

4 Mar 2021

SARS-CoV-2-derived mutant peptides hamper T cells' ability to recognize and destroy infected cells

A deep sequencing study of 747 SARS-CoV-2 virus isolates has revealed mutant peptides derived from the virus that cannot effectively bind to critical proteins on the surface of infected cells and, in turn, hamper activation of CD8+ killer T cells that recognize and destroy these infected cells.

4 Mar 2021

Innovative cancer treatment effective in combating fungal infection in vitro and in mice

An innovative cell-based treatment for cancer has been found promising for the control of infections caused by fungi.

4 Mar 2021

Compound isolated from Moroccan fungus shows promise to fight triple negative breast cancer

A compound isolated from a fungus growing on the roots of a flowering plant in Morocco shows promise as a powerful opponent of aggressive triple negative breast cancer, scientists say.

4 Mar 2021

Life Science News

Immune cells in cerebrospinal fluid could be novel biomarkers of response to immune-based therapies

Scientists optimize wastewater disinfection process to minimize spread of antibiotic resistance

Review helps understand the mechanisms of R-CHOP resistance in diffuse large B-cell lymphoma

Study reveals physical phenomena relied by oocytes to grow big

Researchers call for ecosystem services that are directly linked to species diversity

New, efficient method facilitates antibody development

Researchers identify human BCAS3 and C16orf70 as novel autophagic proteins

Aptamer Group Extends Collaboration With Leading Biopharmaceutical Company to Explore Next-Generation Drug Delivery Approaches

A small sensor can be used for rapid detection of RNA and DNA

New COVID-19 variants can evade antibodies that work against original form of the virus

Study suggests revisiting 14-day limit on human embryo in a dish

Study demonstrates the impact of 'reverse antibiotic' on gram-negative bacteria

SARS-CoV-2 can evade immune response by T-killer cells through mutations

Insight into how plants sense zinc could help cultivate more nutritious crops

Pancreatitis drug blocks SARS-CoV-2 activators in the upper respiratory tract

Researchers decipher how interspecies interactions arise, evolve and are maintained

Proteomics analysis from aggressive human cancers can help identify potential therapeutic targets

SARS-CoV-2-derived mutant peptides hamper T cells' ability to recognize and destroy infected cells

Innovative cancer treatment effective in combating fungal infection in vitro and in mice

Compound isolated from Moroccan fungus shows promise to fight triple negative breast cancer

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest Life Science News