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Valproic acid can interact with DNA conformation and regulate gene expression

Results of recent studies involving valproic acid, used for decades as an anti-convulsant drug, show that it can interact with the conformation of DNA and regulate gene expression.

29 Sep 2020

Study unravels how lysosomal damage response pathways prevent kidney injury

Human cells need to work like well-oiled machines to keep our bodies running as they should. Waste products such as misfolded proteins, damaged cellular components, and carbohydrates get in the way and must be quickly disposed of.

28 Sep 2020

A new generation of microelectrode-array chips for recording nerve cell impulses

ETH researchers have developed a new generation of microelectrode-array chips for measuring nerve impulses, enabling studies of how thousands of nerve cells interact with each other.

28 Sep 2020

Evolutionary and heritable axes shape the organization of brain structure

Every region has its place in the brain. However, it has been unclear why brain regions are located where they are.

28 Sep 2020

Researchers discover specific cellular pathway involved in lung tissue regeneration

Researchers at Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania have identified a cellular pathway that can be targeted with a naturally occurring drug to stimulate lung tissue regeneration, which is necessary for recovery from multiple lung injuries.

28 Sep 2020

Brain wiring genes may be linked to a significant portion of cerebral palsy cases

In an article published in Nature Genetics, researchers confirm that about 14% of all cases of cerebral palsy, a disabling brain disorder for which there are no cures, may be linked to a patient's genes and suggest that many of those genes control how brain circuits become wired during early development.

28 Sep 2020

Blocking nuclear pore complex formation can help selectively kill cancer cells

Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that blocking the construction of nuclear pores complexes--large channels that control the flow of materials in and out of the cell nucleus--shrank aggressive tumors in mice while leaving healthy cells unharmed.

28 Sep 2020

Epigenetic changes in the brain drive late-onset Alzheimer's disease

New findings suggest that late-onset Alzheimer's Disease is driven by epigenetic changes -- how and when certain genes are turned on and off -- in the brain. Results were published today in Nature Genetics.

28 Sep 2020

Scientists identify a new way to regulate cell plasticity

Cell plasticity is a property by which a cell can take on different and reversible identities. Cell plasticity is also essential for embryo development and for the correct function of the immune system.

28 Sep 2020

New mechanism that prevents hair loss identified

A team of researchers from Cologne and Helsinki has discovered a mechanism that prevents hair loss: hair follicle stem cells, essential for hair to regrow, can prolong their life by switching their metabolic state in response to low oxygen concentration in the tissue.

28 Sep 2020

Researchers decipher how the immune system memorizes pathogens after an infection

The immune system will memorize the pathogen after an infection and can therefore react promptly after reinfection with the same pathogen. Now, scientists at the University of Würzburg have deciphered new details of this process.

28 Sep 2020

Research reveals how genetic differences in body fat affect men and women's health risks

New research is revealing how genetic differences in the fat in men's and women's bodies affect the diseases each sex is likely to get.

28 Sep 2020

New framework allows researchers to probe the metabolic processes inside cancer cells

One of the biggest challenges to the development of medical treatments for cancer is the fact that there is no single kind of cancer.

28 Sep 2020

Ascorbic acid: A versatile catalyst for the synthesis of organic compounds

One of the important objectives of green chemistry is the use of eco-friendly solvents and catalysts to perform chemical reactions.

26 Sep 2020

AXT add Vieworks bio-imaging solutions to their preclinical imaging portfolio

AXT is excited to add the Vieworks range of bio-imaging systems to their preclinical imaging product portfolio. Their in-vivo imaging systems provide outstanding performance in bioluminescent and fluorescent imaging and represents excellent value.

From AXT Pty Ltd 26 Sep 2020

Researchers gain deep insights into the structure of birds’ brains

Some birds can perform amazing cognitive feats – even though their forebrains seem to just consist of lumps of grey cells, while mammalian forebrains harbour a highly complex neocortex.

26 Sep 2020

Marine bacteria optimize nutrient uptake by switching between dispersal and resource exploitation

To stay, or not to stay? When it comes to nutrient resource patches, researchers from Japan and Switzerland have discovered that marine bacteria have a knack for exploiting them efficiently, timing movements between patches to get the best resources.

26 Sep 2020

New study links 160 genes to brain shrinkage

A new study implicates 160 genes in brain shrinkage seen on MRIs of 45,000 healthy adults. The shrinkage is in the cortex, the dimply outer layer of the brain that gives rise to thinking, awareness and action, and largely consists of gray matter.

25 Sep 2020

Study identifies hiding place where tumor cells shelter from chemotherapy in childhood leukemia

The stroma of the choroid plexus is one of the locations within the central nervous system (CNS) that serves as a shelter for tumor cells, allowing them to elude chemotherapy and potentially cause subsequent relapses in childhood acute lymphoblastic leukaemia, according to research led by the Complutense University of Madrid.

25 Sep 2020

Researchers develop a stable nano-carrier for medications

Medications often have unwanted side-effects. One reason is that they reach not only the unhealthy cells for which they are intended, but also reach and have an impact on healthy cells.

25 Sep 2020

Life Science News

Valproic acid can interact with DNA conformation and regulate gene expression

Study unravels how lysosomal damage response pathways prevent kidney injury

A new generation of microelectrode-array chips for recording nerve cell impulses

Evolutionary and heritable axes shape the organization of brain structure

Researchers discover specific cellular pathway involved in lung tissue regeneration

Brain wiring genes may be linked to a significant portion of cerebral palsy cases

Blocking nuclear pore complex formation can help selectively kill cancer cells

Epigenetic changes in the brain drive late-onset Alzheimer's disease

Scientists identify a new way to regulate cell plasticity

New mechanism that prevents hair loss identified

Researchers decipher how the immune system memorizes pathogens after an infection

Research reveals how genetic differences in body fat affect men and women's health risks

New framework allows researchers to probe the metabolic processes inside cancer cells

Ascorbic acid: A versatile catalyst for the synthesis of organic compounds

AXT add Vieworks bio-imaging solutions to their preclinical imaging portfolio

Researchers gain deep insights into the structure of birds’ brains

Marine bacteria optimize nutrient uptake by switching between dispersal and resource exploitation

New study links 160 genes to brain shrinkage

Study identifies hiding place where tumor cells shelter from chemotherapy in childhood leukemia

Researchers develop a stable nano-carrier for medications

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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