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Inherited or transmitted gut microbes affect skeletal development in animals

Gut microbes passed from female mice to their offspring, or shared between mice that live together, may influence the animals' bone mass, says a new study published today in eLife.

12 Jan 2021

Study shows how brain molecules work in conjunction to create architectural marvels

In a study published in Cell Reports, researchers at Kanazawa University identify pathways in the brain which enable neurons to assemble into functional units resembling tall columns.

12 Jan 2021

Nanobodies have potential to be developed into a treatment for COVID-19

Researchers at Karolinska Institutet in Sweden have developed, in collaboration with researchers in Germany and the U.S., new small antibodies, also known as nanobodies, which prevent the SARS-CoV-2 coronavirus from entering human cells.

12 Jan 2021

Boosting a natural cellular process could lower ventilator-related lung damage

An unfortunate truth about the use of mechanical ventilation to save the lives of patients in respiratory distress is that the pressure used to inflate the lungs is likely to cause further lung damage.

12 Jan 2021

Advanced humanized mouse model helps better understand immunotherapy resistance in melanoma

Scientists at The Wistar Institute have created an advanced humanized immune system mouse model that allows them to examine resistance to immune checkpoint blockade therapies in melanoma. It has revealed a central role for mast cells. These findings were published today in the journal Nature Communications.

12 Jan 2021

New fluorescence microscopy technique produces nanoscale 3D images of living cells

A new fluorescence microscopy technique has produced the world's first nanoscale 3D images of molecules in a whole, living cell, researchers at KTH Royal Institute of Technology reported.

12 Jan 2021

CN Bio’s PhysioMimix technology receives FDA recognition

CN Bio today announced the publication of co-authored research with the U.S. Food and Drug Administration (FDA)1.

From CN Bio Innovations Ltd 12 Jan 2021

OXGENE introduces SLIM platform for discovery of antibodies against membrane proteins

OXGENE™ announces the introduction of its self-labelling integral membrane (SLIM™) protein discovery system.

12 Jan 2021

Researchers determine the atomic structure of protein that helps coronavirus to evade immune cells

A team of HIV researchers, cellular biologists, and biophysicists who banded together to support COVID-19 science determined the atomic structure of a coronavirus protein thought to help the pathogen evade and dampen response from human immune cells.

12 Jan 2021

Researchers develop improved process for large-scale electron microscopy to visualize small structures

How are networks of neurons connected to make functional circuits? This has been a long-standing question in neuroscience. To answer this fundamental question, researchers from Boston Children's Hospital and Harvard Medical School developed a new way to study these circuits and in the process learn more about the connections between them.

12 Jan 2021

Researchers develop new technique to more efficiently isolate and identify rare T cells

Scientists from the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have developed a technique that will enable researchers to more efficiently isolate and identify rare T cells that are capable of targeting viruses, cancer and other diseases.

12 Jan 2021

Seed-borne bacterium can lead to complete resistance to a particular pathogen

Rice is the staple food of about half the world's population. The cultivation of the rice plant is very water-intensive and, according to the German aid organization Welthungerhilfe, around 15 per cent of rice is grown in areas with a high risk of drought.

12 Jan 2021

Researchers develop a novel, patient-derived model of ulcerative colitis

As reported in Nature Communications, researchers from Cleveland Clinic's Lerner Research Institute have developed a novel, patient-derived model of ulcerative colitis, which will help advance studies into new treatments for the chronic inflammatory bowel disease.

11 Jan 2021

Study monitors spatial shifts of liver gene expression in relationship to the circadian clock

Nothing in biology is static. Biological processes fluctuate over time, and if we are to put together an accurate picture of cells, tissues, organs etc., we have to take into account their temporal patterns. In fact, this effort has given rise to an entire field of study known as "chronobiology".

11 Jan 2021

Researchers demonstrate SARS-CoV-2 infection in human lung bronchioalveolar tissue model

Development of an in vitro human-derived tissue model for studying virus infection and disease progression in the alveolar cells of the lungs responsible for oxygen and carbon dioxide exchange with the blood might enable the study of possible therapies for acute respiratory distress syndrome (ARDS) triggered by SARS-CoV-2.

11 Jan 2021

MDC researchers develop a potent weapon against lymphomas

MDC researchers have developed a new approach to CAR T-cell therapy. The team has shown in Nature Communications that the procedure is very effective, especially when it comes to fighting follicular lymphomas and chronic lymphocytic leukemia, the most common type of blood cancer in adults.

11 Jan 2021

Study sheds new light on the role of MLL4 gene in Kabuki syndrome

Scientists have known for years that mutations in the MLL4 gene can cause Kabuki syndrome, a rare developmental disorder.

11 Jan 2021

Master Regulator proteins control cancer transcriptional identity

Thousands of different genetic mutations have been implicated in cancer, but a new analysis of almost 10,000 patients found that regardless of the cancer's origin, tumors could be stratified in only 112 subtypes and that, within each subtype, the Master Regulator proteins that control the cancer's transcriptional state were virtually identical, independent of the specific genetic mutations of each patient.

11 Jan 2021

Researchers identify bacterium that produces pharmaceutical all-purpose weapon

For some years, an active substance from the leaves of an ornamental plant has been regarded as a possible forerunner of a new group of potent drugs. So far, however, it has been very laborious to manufacture it in large quantities.

11 Jan 2021

Freiburg researchers receive ERC funding to develop and test immunostimulatory drug candidates

With the Proof of Concept funding line, the ERC grants recipients of ERC frontier research funds (Starting, Consolidator, Advanced or Synergy grants) with 150.000 Euro to develop promising ideas with commercial or societal potential to the proof of concept stage.

11 Jan 2021

Life Science News

Inherited or transmitted gut microbes affect skeletal development in animals

Study shows how brain molecules work in conjunction to create architectural marvels

Nanobodies have potential to be developed into a treatment for COVID-19

Boosting a natural cellular process could lower ventilator-related lung damage

Advanced humanized mouse model helps better understand immunotherapy resistance in melanoma

New fluorescence microscopy technique produces nanoscale 3D images of living cells

CN Bio’s PhysioMimix technology receives FDA recognition

OXGENE introduces SLIM platform for discovery of antibodies against membrane proteins

Researchers determine the atomic structure of protein that helps coronavirus to evade immune cells

Researchers develop improved process for large-scale electron microscopy to visualize small structures

Researchers develop new technique to more efficiently isolate and identify rare T cells

Seed-borne bacterium can lead to complete resistance to a particular pathogen

Researchers develop a novel, patient-derived model of ulcerative colitis

Study monitors spatial shifts of liver gene expression in relationship to the circadian clock

Researchers demonstrate SARS-CoV-2 infection in human lung bronchioalveolar tissue model

MDC researchers develop a potent weapon against lymphomas

Study sheds new light on the role of MLL4 gene in Kabuki syndrome

Master Regulator proteins control cancer transcriptional identity

Researchers identify bacterium that produces pharmaceutical all-purpose weapon

Freiburg researchers receive ERC funding to develop and test immunostimulatory drug candidates

How does norepinephrine influence anxiety-related behaviours?

Transforming Lab Workflows with Cell Culture Automation

Building Bridges to Scalable Allogeneic Cell Therapy

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