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Salk study unlocks new way to target hard-to-treat cancers

Now, a new Salk Institute study, published on July 24, 2019, in the journal Science Advances, shows that researchers could target these hard-to-treat cancers by pursuing drugs that keep a cellular "switch," called CREB, from triggering tumor growth.

25 Jul 2019

Weak electron attraction helps hold together amyloid beta sheets found in Alzheimer's

The chemical interactions that give proteins their shape may be weaker and more numerous than previously recognized. These weak connections provide a new way for researchers to understand proteins that cause disease and help them gain insights into the fundamentals of chemistry.

24 Jul 2019

Scientists find surprising insight into Legionnaires’ disease

The incidence of Legionnaires' disease has increased in the past two decades. The natural habitat of Legionella is freshwater biotopes, where they mainly reproduce in amoebae.

24 Jul 2019

Using wavelength-encoded laser particles to tag tumor cells

A new study, "Wavelength-encoded laser particles for massively multiplexed cell tagging," by scientists in the Wellman Center for Photomedicine has been published in Nature Photonics.

24 Jul 2019

Researchers identify cells required for formation of a functioning uterus

Knowledge of the biological processes involved in the development of the uterus is important for understanding uterine health and fertility.

24 Jul 2019

Scientists discovered reason why microbes adopt "public goods" approach

Scientists have given a fascinating new insight into the way microbes adopt a 'co-operative' approach to securing the nutrients they need to thrive.

24 Jul 2019

Study finds hidden dynamics in neuronal networks

Neuronal networks in the brain can process information particularly well when they are close to a critical point - or so brain researchers had assumed based on theoretical considerations.

23 Jul 2019

Common feature that makes cancer cells appear bloated could be their potential weak spot

In a study using yeast cells and data from cancer cell lines, Johns Hopkins University scientists report they have found a potential weak spot among cancer cells that have extra sets of chromosomes, the structures that carry genetic material.

23 Jul 2019

Porvair Sciences extends ultra-clean deep well plate range

Porvair Sciences has extended its sample storage and collection range with the introduction of 5 new deep well microplates.

From Porvair Sciences Limited 23 Jul 2019

DCCNet demonstrates use of Parsortix system for single cell CTC analysis

ANGLE plc, a world-leading liquid biopsy company, is pleased to announce that one of its leading customers, the Disseminated Cancer Cell Network, Duesseldorf, an interdisciplinary team of cancer researchers and clinicians, has published new results in a peer-reviewed journal of work done to develop a “robust, reliable and cost-efficient workflow” for enrichment of single circulating tumor cells.

23 Jul 2019

Exosomes can restore health to brain cells affected by developmental disease

Like overpacked suitcases unloaded from the underbelly of a jet, molecular satchels called exosomes are continuously deployed from all cells in the body—each one brimming with an assortment of contents that another cell may unpack and use.

23 Jul 2019

High-resolution images offer clues to improve design of anti-nausea drugs

A new study using a special type of electron microscope using samples cooled to extremely cold temperatures provides critical information for drug developers seeking to reduce nausea and vomiting side effects of cancer treatments.

23 Jul 2019

UV-DDB protein scouts DNA damage and oversees repair

In the time it takes you to read this sentence, every cell in your body suffers some form of DNA damage. Without vigilant repair, cancer would run rampant, and now scientists at the University of Pittsburgh have gotten a glimpse of how one protein in particular keeps DNA damage in check.

22 Jul 2019

Researchers identify toxin responsible for Legionella growth

A team of scientists led by EMBL group leader Sagar Bhogaraju and Ivan Dikic of Goethe University, Frankfurt, discovered that the toxin SidJ in Legionella bacteria enforces a unique modification on human proteins and helps legionella grow inside human cells.

22 Jul 2019

Researchers identify new mechanism for deactivation of switch proteins

A new mechanism for the deactivation of switch proteins has been identified by researchers from Ruhr-Universität Bochum, headed by Professor Klaus Gerwert and Dr. Till Rudack from the Department of Biophysics, and the University of Uppsala in Sweden.

22 Jul 2019

Servier chooses Pall as single-source supplier for new biomanufacturing facility

Pall Corporation, a global leader in filtration, separation and purification, has been chosen by Servier, an independent international pharmaceutical company, as an exclusive technology and services provider for their Gidy, France biomanufacturing facility.

From Pall Corporation 22 Jul 2019

BIA Separations selected to support AveXis’ gene therapy pipeline

BIA Separations, a leading biochromatography development and manufacturing company, today announced it is collaborating with AveXis, a Novartis company, to enhance the commercial purification process for its gene therapy pipeline, beginning with Zolgensma (onasemnogene abeparvovec-xioi), the first U.S. Food and Drug Administration-approved gene therapy indicated for the treatment of pediatric patients with spinal muscular atrophy (SMA) who are less than two years of age.

22 Jul 2019