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Canadian researchers uncover new molecular mechanism to stop proliferation of cancer cells

Canadian researchers have discovered a new and direct molecular mechanism to stop cancer cells from proliferating. In the prestigious journal Nature Cell Biology, scientists from Université de Montréal show that a disruption of a fine balance in the composition of ribosomes (huge molecules that translate the genetic code into proteins) results in a shutdown of cancer cell proliferation, triggering a process called senescence.

26 Jun 2018

AbbVie and Calibr collaborate to develop T-cell therapies aimed at cancer

AbbVie , a research-based global biopharmaceutical company, and Calibr, a nonprofit drug discovery division of Scripps Research, today announced a collaboration to develop T-cell therapies aimed primarily at cancer, including solid tumors.

25 Jun 2018

Oxygen-starved tumors have an Achilles' heel that could be targeted with drugs

A tumor's goal is simple: to grow, grow, grow, by making more cancer cells. But that often means growing so fast that the oxygen supply gets scarce, at which point cells within the tumor start to suffocate.

25 Jun 2018

New discovery suggests potential target for treating cancers and other diseases

When cells grow and divide to ensure a biological function - such as a properly working organ - DNA must be unwound from its typical tightly packed form and copied into RNA to create proteins.

25 Jun 2018

Lund researchers develop fluorescent variant of a molecule that inhibits cancer stem cells

A team of researchers at Lund University in Sweden has developed a fluorescent variant of a molecule that inhibits cancer stem cells.

25 Jun 2018

Researchers use gene editing to reduce autism symptoms in mice

Researchers have used CRISPR-Cas9 gene editing to treat symptoms of autism in mice. It is hoped that the tool could one day be used to help humans.

25 Jun 2018

Blocking viral-host interaction slows down flu virus replication, study shows

Influenza A (flu A) hijacks host proteins for viral RNA splicing and blocking these interactions caused replication of the virus to slow, according to new research published in Nature Communications by Kristin W. Lynch, PhD, chair of the department of Biochemistry and Biophysics in the Perelman School of Medicine at the University of Pennsylvania, and doctoral student Matthew Thompson.

25 Jun 2018

Mice learn to plan ahead and avoid future regrets

Experiencing regret can leave a “bad taste” in one’s mouth and drive an individual to compensate for one’s losses. This immediate post-regret phenomenon was once thought to be unique to humans, but it has been recently demonstrated in other species. However, it was previously unknown if other species are capable of learning from these mistakes over time.

25 Jun 2018

Dynamic model helps make predictions about gut microbiome

The human gut is teeming with microbes, each interacting with one another in a mind-boggling network of positive and negative exchanges. Some produce substances that serve as food for other microbes, while others produce toxins - antibiotics - that kill their neighbors.

22 Jun 2018

Researchers discover drug compound that inhibits movement of cancer cells

Fighting cancer means killing cancer cells. However, oncologists know that it's also important to halt the movement of cancer cells before they spread throughout the body.

22 Jun 2018

Study: Inner nuclear envelope plays role in lipid metabolism

The cell nucleus is an organelle, in which the DNA of an organism is protected and duplicated. The nucleus of this organ-like structure in the cell plasma is surrounded by an outer and an inner nuclear envelope, which is penetrated by openings - so-called nuclear pores.

22 Jun 2018

Morgridge researchers develop portable, shareable light sheet microscope

Modern microscopy has given scientists a front-row seat to living, breathing biology in all its technicolor glory. But access to the best technologies can be spotty.

22 Jun 2018

Researchers diagnose cerebral palsy using AI and next-generation sequencing

Researchers have shown that patients with spastic cerebral palsy (CP) can be identified using DNA methylation patterns in circulating blood cells.

22 Jun 2018

Porvair Sciences introduces new stackable rack for 12mm vials and tubes

Porvair Sciences has introduced the JG Finneran 50-position stackable rack for 12 mm vials and tubes. This new stackable rack is designed to hold 12mm vials and tubes in the optimum orientation for pipetting tasks.

From Porvair Filtration Group Ltd. 22 Jun 2018

Minakem's new high-class production facility extends capacity to develop and manufacture HPAPI compounds

Minakem, the CDMO division of Minafin, specialized in custom development and manufacturing of building blocks, GMP intermediates and Active Pharmaceutical Ingredients, today announces it is in the final qualification run to open a new closed-controlled environment high containment production facility in August.

22 Jun 2018

Investigating the Unique Nanomechanical Properties of Tooth Enamel

My background is in tribology, which is the science of the interactions between surfaces in relative motion. This involves looking at behaviour, such as friction, wear and lubrication, and the relationships between them.

From Bruker Nano Surfaces and Metrology 22 Jun 2018

Technical paper provides information on how to specify liquid flowmeters

Titan Enterprises has produced an informative technical paper - 'How to specify liquid flowmeters'.

From Titan Enterprises Ltd 22 Jun 2018

CellGenix completes first phase of facility expansion to meet rising demands for GMP cell culture reagents

CellGenix, a global manufacturing leader of GMP-grade raw materials for cell therapy, gene therapy and tissue-engineered products, successfully completed the first phase of its headquarters’ expansion as more customers approach late-stage clinical development and commercialization.

22 Jun 2018

Distek, Inc. launches revolutionary benchtop scale bioreactor

Distek, Inc. has revolutionized benchtop scale bioreactors with the release of our BIOne 1250 bioprocess control station for both mammalian and microbial models.

22 Jun 2018

Study provides clues to how cancer cells develop resistance to chemotherapies

About half of all drugs, ranging from morphine to penicillin, come from compounds that are from - or have been derived from - nature. This includes many cancer drugs, which are toxic enough to kill cancer cells.

22 Jun 2018