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Finasteride Mechanism

In healthy males, testosterone is produced primarily by the testes and in small amounts by the adrenal glands. Most of the testosterone is transported bound to a specific plasma protein called sex hormone binding globulin (SHBG). This protein is produced in the liver and carries the sex hormones (androgens in males and estrogens in females) to their site of action in the body.

13 Apr 2010

Finasteride Side Effects

Finasteride is an anti-androgen agent used to treat benign prostatic hyperplasia and male pattern baldness. This medication works by inhibiting the 5 alpha reductase enzyme that converts the male sex hormone testosterone into its more potent form, dihydrotestosterone (DHT).

13 Apr 2010

What is Finasteride?

Finasteride is an anti-androgen agent used to treat benign prostatic hyperplasia and male pattern baldness. Some of the brand names finasteride is sold under include Proscar, Fincar, Propecia, Finpecia, Finast, Finax, Finara, Finalo and Prosteride.

13 Apr 2010

Barbiturate Abuse

Barbiturates were first used in 1903. They are derivatives of the chemical molecule barbituric acid. There are over 2000 derivatives of barbituric acid that have been used in medicine.

13 Apr 2010

Barbiturate Risks

Barbiturates once enjoyed vast popularity as sedatives and sleep inducing agents. Over time their side effects led to more caution and at present these agents are seldom prescribed for insomnia and sleep disorders.

13 Apr 2010

Barbiturate Mechanism

Barbiturates may have been abandoned as sedatives and tranquillizers due to their high abuse and dependence potential and risk of side effects, but they continue to hold an important place in neurology practice today.

13 Apr 2010

Barbiturate History

Sleep disorders have been managed using several means throughout the history of mankind. It all began with alcohol and alkaloids of opium and other narcotic plants (hemp, belladonna, henbane, etc). It was in the late 19th and early 20th centuries that drugs such as paraldehyde, chloral hydrate, and bromides were developed for induction and maintenance of sleep.

13 Apr 2010

What are Barbiturates?

Barbiturates are synthetic drugs used in medicine to depress the central nervous system.

13 Apr 2010

Ribavirin Adverse Effects

Ribavirin represents a nucleotide analog of guanosine and a broad-spectrum direct antiviral agent.

12 Apr 2010

Ribavirin Pharmacokinetics

Ribavirin is a broad spectrum antiviral agent predominantly used in the treatment of hepatitis C and respiratory syncytial virus (RSV) infections. The exerted antiviral effect depends substantially on dosage and plasma concentration of the drug, thus its pharmacokinetic properties (together with the underlying mechanisms of action) may be the key the identification of improved therapeutic protocols.

12 Apr 2010

Ribavirin Mechanism

Ribavirin is a broad-spectrum antiviral nucleoside .

12 Apr 2010

Ribavirin Derivatives

Ribavirin (1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide) is a purine analogue and a commonly used antiviral agent against both RNA and DNA viruses. With up to five suggested mechanisms of action, latest advances have begun to differentiate the hierarchy of antiviral effects at play depending on the virus and the host conditions under scrutiny.

12 Apr 2010

Ribavirin Chemistry

Ribavirin, the nucleoside analog 1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide, is a broad spectrum direct antiviral agent. This drug was discovered more than 40 years ago and is efficient both in vitro and in vivo against several RNA or DNA viruses.

12 Apr 2010

Ribavirin History

Ribavirin is a guanosine analog that produces broad-spectrum activity against different RNA and DNA viruses.

12 Apr 2010

Ribavirin Marketing

Ribavirin is an antiviral agent used in the treatment of chronic hepatitis C virus infection that also shows activity against respiratory syncytial virus (RSV). In the United States, ribavirin is FDA-approved and marketed as inhalation solution for treating of RSV infection, and as oral capsule and tablet for the treatment of hepatitis C virus infection.

12 Apr 2010