Nidhi Saha

Impact of SARS-CoV-2 on oral health

New research examined SARS-CoV-2 and its impact on oral health and suggests that survival against the infection may be partially dependent on such factors.

Increased illness burden of COVID-19 among unvaccinated first responders

A new study gathered data from the HEROES-RECOVER prospective cohorts and reported an increased illness burden of COVID-19 among unvaccinated first responders.

COVID-19 vaccination coverage and breakthrough infections in urban slums of India

A new study aimed to identify COVID-19 vaccination coverage, examine the factors responsible for COVID-19 vaccination coverage and vaccine hesitancy, study adverse events following immunization patterns after COVID-19 vaccination and determine the prevalence of breakthrough infection after COVID-19 vaccination.

Breakthrough infections from SARS-CoV-2 Delta variant among vaccinated healthcare workers

A new study published on the medRxiv* preprint server employed in-silico techniques, combining genomic and epidemiological data, to determine possible Delta-variant transmission events between vaccinated healthcare workers (HCWs) in Indian hospitals.

Serum SARS-CoV-2 antigen: A better predictor of COVID-19 severity

In this perspective, a new study published on the medRxiv* preprint server analyzed the clinical efficacy of two serum antigen tests to identify SARS CoV-2 infection and evaluate the kinetics of serum nucleocapsid (N) antigen in severe and non-severe patients for disease severity prediction.

Limited immune responses three months after Pfizer-BioNTech vaccination among elderly

In this study, published on the medRxiv* preprint server, the humoral response to SARS-CoV-2 was assessed before and after three months of administration of the BNT162b2 mRNA COVID-19 vaccination (Pfizer-BioNTech). In addition, elders' humoral responses were compared to those of a younger group, and a functional neutralization experiment against the Wuhan-Hu-1 (WH1) virus and the Delta variant was carried out.

Vaccine-induced immune responses for SARS-CoV-2 in patients receiving anti-CD20 B-cell depleting therapies

A new study published on the medRxiv* preprint server analyzed the trajectories of anti-SARS-CoV-2 antibodies in patients from the RituxiVac study were compared to healthy volunteers. In addition, they investigated the immunogenicity of a third vaccine dose in previously non-responding patients.

A canine coronavirus zoonotic spillover and tropism shift

Effectiveness of COVID-19 vaccination during Delta variant predominance

A new study investigated the continued effectiveness of COVID-19 vaccination during the delta variant predominance in a diverse and urban healthcare setting.

Population-based risk compensation may have been a driving force in UK's COVID pandemic

The COVID-19 pandemic has irreversibly altered our lives in many ways. However, available COVID vaccines are effective against (symptomatic) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, hospitalizations, and even death. Despite a diminishing protective effect against infection and onward transmission after vaccination, and a slightly diminished effect with the Delta variant compared to the Alpha variant, protection against severe outcomes remains high.