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Genetic study: Novel coronavirus most closely related to viruses in bats

The virus that is causing alarm among global public health authorities after it killed a man in Jeddah, Saudi Arabia earlier this year and is now linked to two other cases of disease is a novel type of coronavirus most closely related to viruses found in bats, according to a genetic analysis to be published in mBio-, the online open-access journal of the American Society for Microbiology, on November 20.

22 Nov 2012

FDA accepts MAP Pharmaceuticals’ resubmission of NDA for LEVADEX

MAP Pharmaceuticals, Inc. today announced that its New Drug Application (NDA) resubmission for LEVADEX orally inhaled migraine drug for the potential acute treatment of migraine in adults has been accepted for filing by the U.S. Food and Drug Administration (FDA).

22 Nov 2012

UH professor named American Mathematical Society fellow for 2013

From a field of mathematical scientists from more than 600 institutions around the world, University of Houston (UH) professor Roland Glowinski has been named a fellow of the American Mathematical Society (AMS) for 2013, the program's inaugural year. The prestigious program recognizes AMS members who have made outstanding contributions to the creation, exposition, advancement, communication and utilization of mathematics.

21 Nov 2012

UPR pathway helps tumor cells escape apoptosis during development of lymphoma

A pathway called the "Unfolded Protein Response," or UPR, a cell's way of responding to unfolded and misfolded proteins, helps tumor cells escape programmed cell death during the development of lymphoma.

21 Nov 2012

Cynosure closes underwritten registered public offering of class A common stock

Cynosure, Inc., a leader in laser- and light-based treatments for minimally invasive and non-invasive aesthetic applications, today announced the closing of its previously announced underwritten registered public offering of class A common stock.

21 Nov 2012

No differences between computer-navigated and traditional TKA related to knee function, pain

For many years, the use of computer-assisted navigation has been touted as improving the positioning, sizing and alignment of replacement knee joints, resulting in greater durability of joints and overall improvement in patient movement. However, new research published in the Journal of Bone and Joint Surgery (JBJS) found no difference in knee function, alignment or durability/survivorship between joints positioned and completed with the help of computer navigation, and those replaced with conventional total knee arthroplasty (TKA) procedures.

21 Nov 2012

Rexahn's quinoxalinyl-piperazine compounds receive U.S. patent

Rexahn Pharmaceuticals, Inc., a clinical stage pharmaceutical company dedicated to developing and commercializing first-in-class oncology therapeutics, today announced that it has been issued a United States patent (No. 8,314,100), titled "1-[6,7-substituted alkoxyquinoxalinyl) aminocarbonyl]-4-(hetero) arylpiperazine derivatives."

21 Nov 2012

Reckitt Benckiser to acquire Schiff

Reckitt Benckiser Group PLC today announces it has signed a definitive merger agreement with Schiff Nutrition International, Inc. a leading provider of branded vitamins, nutrition supplements and nutrition bars in the United States and elsewhere. The Board of Directors of Schiff has approved the transaction and will recommend that its stockholders tender their shares into Reckitt Benckiser's previously announced cash tender offer of $42.00 per share, valuing Schiff at $1.4 billion.

21 Nov 2012

Regorafenib able to control resistant gastrointestinal stromal tumor

A new targeted drug demonstrated its ability to control metastatic gastrointestinal stromal tumor, an uncommon and life-threatening form of sarcoma, after the disease had become resistant to all existing therapies, report investigators at Dana-Farber Cancer Institute who led the worldwide clinical trial.

21 Nov 2012

Australian TGA approves Genzyme’s AUBAGIO to treat relapsing forms of multiple sclerosis

Genzyme, a Sanofi company, announced today that the Australian Therapeutic Goods Administration (TGA) has approved AUBAGIO (teriflunomide) 14 mg as a new once-daily, oral treatment indicated for patients with relapsing forms of multiple sclerosis (MS).

21 Nov 2012

Viewpoints: Protecting us from counterfeit medicines; Governors making excuses on insurance exchanges?; Simpson-Bowles and the health law

HHS has made it clear that after federally operated exchanges are up and running, states may eventually take over operations. This seems like wasted effort. States have the information they need to move on insurance exchanges. Governors who care about fiscal responsibility, strong state government and the basic welfare of their residents would do well to get with the program.

21 Nov 2012

Promising results for pneumococcal vaccine

Research published in The Lancet shows that the PHiD-CV10 vaccine is highly effective at protecting children against invasive pneumococcal disease.

21 Nov 2012

Poor oral health linked to severe mental health issues

UK study results show that individuals with severe mental illness who live in the community and receive community-based psychiatric care have poorer oral health than the national adult population.

21 Nov 2012

Scars mark hypertension risk in vesicoureteral reflux

Renal scarring associated with vesicoureteral reflux is a significant risk factor for developing hypertension, shows a study of pediatric patients.

21 Nov 2012

Flame retardants may cause neurodevelopmental problems in children

Children exposed to high levels of polybrominated diphenyl ethers either prenatally or during childhood have poorer attention, fine motor coordination, and intelligence quotients than those exposed to low levels, show results from two studies.

21 Nov 2012

Cryoprecipitate plus tranexamic acid boost war injury survival

Administration of cryoprecipitate and tranexamic acid significantly improves the likelihood of survival among seriously injured patients requiring packed red blood cells, suggest results from MATTERS II.

21 Nov 2012

Metabolomics clue to postoperative delirium

The choice of general anesthetic in children influences their cerebral metabolism, which in turn affects their risk for postoperative delirium, an imaging study shows.

21 Nov 2012

Alternatives to colonoscopy for monitoring colorectal cancer risk

Researchers have found that there are effective alternatives to colonoscopy screening for managing people who have received an initial negative colonoscopy result for colorectal cancer.

21 Nov 2012

Watch-and-wait approach feasible following adjuvant therapy for rectal cancer

Patients with rectal cancer managed conservatively following a complete response to chemoradiotherapy achieve similar rates of disease control as those who undergo rectal resection, research shows.

21 Nov 2012

Personality influences placebo response

Researchers have found that resilient, altruistic, and straightforward individuals are significantly more likely to respond to a sham painkilling or placebo injection than those who are angry and hostile.

21 Nov 2012