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Adding angiogenesis inhibitor to anti-HER2 drugs extends survival in mice with breast cancer

Adding an angiogenesis inhibitor to treatment with a HER2-inhibiting drug could improve outcomes for patients with HER2-positive breast cancer who develop brain metastases. In their report published online in PNAS Plus, Massachusetts General Hospital (MGH) investigators report the first preclinical study combining antiangiogenic and anti-HER2 drugs in an animal model of brain metastatic breast cancer.

3 Nov 2012

NCAR launches study into impact of open-fire cooking on regional air quality and disease

Expanding its focus on the link between the atmosphere and human health, the National Center for Atmospheric Research (NCAR) is launching a three-year, international study into the impact of open-fire cooking on regional air quality and disease.

3 Nov 2012

Scientists sequence and analyze human genomes to discover many variants

Thanks to powerful computational tools developed at Simon Fraser University, more than 100 scientists from around the world have genetically mapped the largest and most varied number of human genomes to date.

3 Nov 2012

Intensified antibiotic treatment can improve prognosis of patients with TB meningitis

Researchers from the Radboud UMC have conducted the first study globally to show that intensified antibiotic treatment can improve the prognosis of patients with tuberculous (TB) meningitis, the most severe form of TB which carries a mortality of up to 50%.

3 Nov 2012

Baylor University receives two new federal grants for research on Gulf War illness

Baylor University has been awarded two new federal grants for research on Gulf War illness, the complex medical condition that affects veterans of the 1991 war. The grants, from the Office of Congressionally Directed Medical Research Programs of the U.S. Department of Defense, total nearly $1.6 million, and bring current federal funding for Baylor's Gulf War research program to over $2.3 million.

3 Nov 2012

Forecasting health policy for the post-election landscape

Various news stories examine how the outcome of the presidential election could lead to very different courses for the health law's implementation and approaches to Medicare reform.

3 Nov 2012

AeriSeal System appears to be effective in treating emphysema

Researchers at the University of Alabama at Birmingham injected a foam sealant into the lungs of a former smoker on Oct. 29, 2012, to treat his worsening emphysema. He was the first patient in the United States treated in a late-stage clinical trial of the AeriSeal System.

3 Nov 2012

Mass spectrometry can help visualize how drugs work inside living cells to kill infectious microbes

Weill Cornell Medical College researchers report that mass spectrometry, a tool currently used to detect and measure proteins and lipids, can also now allow biologists to "see" for the first time exactly how drugs work inside living cells to kill infectious microbes.

3 Nov 2012

Studies show standardizing computer programs help improve genetic testing for Lynch Syndrome

Many patients who have genetic testing for Lynch syndrome, a hereditary predisposition to colon cancer, receive the inconclusive result "variants of uncertain clinical significance."

3 Nov 2012

Hospital for Special Surgery physical therapist offers marathon recovery tips

Close to 47,000 runners have spent the past several months training for the ING New York City Marathon. Once they have completed the race and achieved their goals, there are measures they can take to facilitate recovery, decrease post-race discomfort, and return to running without injury.

3 Nov 2012

GHDonline provides virtual discussion on health care delivery

Sarah Arnquist, who runs Global Health Hub, writes in Harvard University's Global Health Delivery Project blog about a Monday session at the American Public Health Association's annual conference that discussed "using online communities to promote health and engage communities -- of either professionals or patients."

3 Nov 2012

Treatments and outcomes vary for nursing home residents who use Medicare SNF care: Study

A Medicare rule that blocks thousands of nursing home residents from receiving simultaneous reimbursement for hospice and skilled nursing facility care at the end of life may result in those residents receiving more aggressive treatment and hospitalization, according a new analysis.

3 Nov 2012

Toilet training method not related to urinary accidents in children

Parents: stop worrying about which toilet training method to use - where urinary accidents in children are concerned, it doesn't matter. This clearly-stated message, published today in Clinical Pediatrics by physician researchers from the University of Medicine and Dentistry of New Jersey (UMDNJ)-Robert Wood Johnson Medical School and The Bristol-Myers Squibb Children's Hospital at Robert Wood Johnson University Hospital, emphasizes that the method of training chosen by parents is not the cause of urinary accidents in children.

3 Nov 2012

Bypass surgery offers people with diabetes better long-term survival than stents

People with diabetes mellitus who undergo heart bypass surgery for multiple blocked arteries have a significantly better 5-year-survival rate than diabetic patients who undergo angioplasty with drug-eluting stents (DES), according to a study published in the November 2012 issue of The Annals of Thoracic Surgery.

3 Nov 2012

Resolve to fight TB must be strengthened in U.S. global AIDS blueprint

As part of its "Blueprint" series discussing the creation of a U.S. global AIDS blueprint called for by Secretary of State Hillary Clinton in July, the Center for Global Health Policy's "Science Speaks" blog features an opinion piece by Salmaan Keshavjee of Harvard Medical School and Partners In Health. With an estimated 1,000 people with HIV dying of tuberculosis (TB) every day, "it is clear that our current approaches to addressing the global tuberculosis pandemic are inadequate," he writes.

3 Nov 2012

Researcher identifies 71 genetic regions newly associated with inflammatory bowel disease

In one of the largest studies of its kind ever conducted, an international team of scientists has thrown new light on the genetic basis of the inflammatory bowel diseases (IBD).

3 Nov 2012

Physicists to bring to market new drug-discovery tool using genetic sequencing

Today physicists at Wake Forest University and NanoMedica, their biotechnology company partner, received a $700,000 grant from the National Institutes of Health to bring to market a new drug-discovery tool using next-generation genetic sequencing.

3 Nov 2012

Hurricane Sandy's aftermath leaves older adults particularly vulnerable

Older adults left in the wake of Hurricane Sandy will likely suffer disproportionately in the days ahead, based on data from other recent natural disasters.

3 Nov 2012

Phase II study to evaluate Medivir/Janssen's simeprevir and Vertex against HCV

Medivir AB, announced today plans for a phase II proof-of-concept study of an all-oral regimen for the treatment of hepatitis C containing of Medivir/Janssen's protease inhibitor simeprevir and Vertex's nucleotide analogue hepatitis C virus (HCV) polymerase inhibitor VX-135.

3 Nov 2012

Health experts gather in Sydney for 3-day malaria conference

"More than 200 health experts have gathered in Sydney for a three-day conference to bolster political commitment to tackle the spread of malaria," IRIN reports.

3 Nov 2012

Medical News

Adding angiogenesis inhibitor to anti-HER2 drugs extends survival in mice with breast cancer

NCAR launches study into impact of open-fire cooking on regional air quality and disease

Scientists sequence and analyze human genomes to discover many variants

Intensified antibiotic treatment can improve prognosis of patients with TB meningitis

Baylor University receives two new federal grants for research on Gulf War illness

Forecasting health policy for the post-election landscape

AeriSeal System appears to be effective in treating emphysema

Mass spectrometry can help visualize how drugs work inside living cells to kill infectious microbes

Studies show standardizing computer programs help improve genetic testing for Lynch Syndrome

Hospital for Special Surgery physical therapist offers marathon recovery tips

GHDonline provides virtual discussion on health care delivery

Treatments and outcomes vary for nursing home residents who use Medicare SNF care: Study

Toilet training method not related to urinary accidents in children

Bypass surgery offers people with diabetes better long-term survival than stents

Resolve to fight TB must be strengthened in U.S. global AIDS blueprint

Researcher identifies 71 genetic regions newly associated with inflammatory bowel disease

Physicists to bring to market new drug-discovery tool using genetic sequencing

Hurricane Sandy's aftermath leaves older adults particularly vulnerable

Phase II study to evaluate Medivir/Janssen's simeprevir and Vertex against HCV

Health experts gather in Sydney for 3-day malaria conference

Voltammetry and machine learning for real-time neurotransmitter detection

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

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