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TransTech Pharma to complete TTP054 Phase 2 trial on type 2 diabetes

TransTech Pharma, Inc., announced today that recruitment of patients for its recently initiated, multi-center Phase 2 clinical trial of TTP054 in type 2 diabetics, is exceeding expectations with initial top line results available in early 2013. The 90-day proof of concept study is being conducted in type 2 diabetics not well controlled with approved oral anti-diabetic agents.

2 Nov 2012

Roundup: Texas will keep Planned Parenthood Women's Health Program for now; Kids' autism covered in Wash. Medicaid; UnitedHealth selling S.C. Medicaid biz

Planned Parenthood will continue to receive funds from a joint Texas and federal program providing health care to low-income women, despite the state's promise to exclude its clinics by Nov. 1 because they are affiliated with abortion providers.

2 Nov 2012

Oskar gene emerged far earlier in insect evolution than previously believed

Harvard scientists have solved the long-standing mystery of how some insects form the germ cells - the cellular precursors to the eggs and sperm necessary for sexual reproduction - and the answer is shedding new light on the evolutionary origins of a gene that had long been thought to be critical to the process.

2 Nov 2012

Malarial drug shows promise in stopping breast cancer

A malarial drug is showing promise in stopping breast cancer before it starts, Mason researchers are discovering during a clinical trial.

2 Nov 2012

Apolipoprotein E plays a major role in maintaining arterial softness

Arterial stiffening has long been considered a major risk factor for cardiovascular disease. Keeping arteries soft and supple might reduce disease risk, but the mechanisms of how arteries stave off hardening has remained elusive.

2 Nov 2012

Inotek announces final data from trabodenoson Phase 2 trial on PAOG or ocular hypertension

Inotek Pharmaceuticals Corp., a leader in the development of innovative drug candidates to address significant diseases of the eye, today announced that final data from a Phase 2 clinical trial of trabodenoson, also known as INO-8875, in patients with primary open-angle glaucoma or ocular hypertension will be presented at the Ophthalmology Innovation Summit on Thursday, November 8, 2012 at the Chicago Marriott Downtown Magnificent Mile in Chicago, IL.

2 Nov 2012

High blood cholesterol far more common than previously recognized

High blood cholesterol, a serious hereditary disease, is far more common than previously recognised and not treated sufficiently.

2 Nov 2012

NJH researchers discover novel target for treatment of food allergies

Researchers at National Jewish Health have discovered a novel target for the treatment of food allergies. Erwin Gelfand, MD, and his colleagues report in the October 2012 issue of the Journal of Allergy and Clinical Immunology that levels of the enzyme Pim 1 kinase rise in the small intestines of peanut-allergic mice. Inhibiting activity of Pim 1 markedly reduced the allergic response to peanuts.

2 Nov 2012

Study explores impact of IL1β on brain function alterations associated with schizophrenia

There are a growing number of clues that immune and inflammatory mechanisms are important for the biology of schizophrenia. In a new study in Biological Psychiatry, Dr. Mar Fatjó-Vilas and colleagues explored the impact of the interleukin-1β gene (IL1β) on brain function alterations associated with schizophrenia.

2 Nov 2012

FDA clears Accuray’s new CyberKnife M6 Series

Accuray Incorporated, the premier radiation oncology company, today announced that the company received 510(k) clearance from the U.S. Food and Drug Administration (FDA) for its new CyberKnife M6 Series.

2 Nov 2012

Viewpoints: George Will: Dems' 'reservoir of condenscension' focused on women; One disabled voter questions assisted suicide referendum

Much of the Democratic Party's vast reservoir of condescension is currently focused on women, who are urged not to trouble their pretty little heads about actual problems but instead to worry that, 52 years after birth control pills went on the market and 47 years after access to contraception became a constitutional right, reproductive freedom is at risk. This insult may explain the shift of women toward Romney.

1 Nov 2012

Club foot ankle osteoarthritis risk revealed

Patients treated for clubfoot have a low long-term risk for ankle osteoarthritis, say Swedish researchers after studying patients aged over 60 years.

1 Nov 2012

Cardio exercise OK in high-risk CVD patients

US study results indicate that cardiopulmonary exercise is well tolerated, even when performed by individuals with high-risk cardiovascular disease.

1 Nov 2012

Better access to fresh, local food urged for underprivileged families

Initiatives that improve the ability of socially disadvantaged families to obtain local produce are sorely needed, say US researchers.

1 Nov 2012

Partial dentin removal superior to stepwise excavation over long term

Partial caries removal treatment for individuals with deep caries lesions results in significantly improved pulp vitality after 3 years than does stepwise excavation, indicate Brazilian study findings.

1 Nov 2012

Aerobic exercise may offer new treatment option for ADHD

Research suggests that moderate aerobic exercise may offer a new treatment option for children with attention deficit/hyperactivity disorder.

1 Nov 2012

Implant-based breast reconstruction has disadvantages

Implant-based breast reconstruction, particularly immediate reconstruction, is associated with a higher failure rate than a free flap technique in obese people, suggest researchers.

1 Nov 2012

FoXTROT results: preoperative chemo could become new standard

Preoperative chemotherapy is a feasible option for resectable advanced colon cancer, show results of the FoXTROT trial.

1 Nov 2012

Bone quality reduced in mood disorder patients

Results from an Australian study show that men and young women with mood disorders have significantly lower bone quality than their mentally healthy counterparts.

1 Nov 2012