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B-cell substances may play a role in MS progression

Wayne State University School of Medicine researchers, working with colleagues in Canada, have found that one or more substances produced by a type of immune cell in people with multiple sclerosis (MS) may play a role in the disease's progression. The finding could lead to new targeted therapies for MS treatment.

2 Aug 2012

Financial viability of Social Security is in jeopardy because of outdated forecasting methods

The Social Security Trust Fund is off on its prediction by $730 billion for needed benefits in 2030. That is because its forecasting methods have hardly been updated since 1935 when the program first started, according to a study in the August issue of Demography.

2 Aug 2012

In rare compromise, Hill leaders agree on temporary spending deal to keep government running through next March

The tentative deal would prevent a government shutdown before Election Day. Modern Healthcare reports, though, that the agreement does not include any changes or fixes to the physician payment formula - which will require a 27% cut in payments to Medicare physicians next year.

2 Aug 2012

Possible molecular link between circadian rhythm disturbances and increased inflammatory response

Scientists have known for some time that throwing off the body's circadian rhythm can negatively affect body chemistry. In fact, workers whose sleep-wake cycles are disrupted by night shifts are more susceptible to chronic inflammatory diseases such as diabetes, obesity and cancer.

2 Aug 2012

Scientists discover critical molecular switch that regulates autophagy

The body has a built-in system known as autophagy, or 'self-eating,' that controls how cells live or die. Deregulation of autophagy is linked to the development of human diseases, including neural degeneration and cancer.

2 Aug 2012

Report provides two distinct views of behavioral healthcare delivery

Behavioral healthcare systems are playing a major role in responding to the needs of the millions of Americans of all ages who experience psychiatric and substance use conditions each year, according to the latest annual survey from the National Association of Psychiatric Health Systems (NAPHS) released today.

2 Aug 2012

New FDA risk management plan aims to reduce opioid abuse in the U.S.

A new risk management plan from the U.S. Food and Drug Administration to help clinicians properly prescribe drugs with addiction potential aims to help reduce the growing epidemic of opioid abuse in the United States.

2 Aug 2012

Medical staff struggle to spot problem drinkers unless they are already intoxicated

Medical staff struggle to spot problem drinking in their patients unless they are already intoxicated, according to research by the University of Leicester.

2 Aug 2012

Three papers focus on nucleosomes and may help uncover the rules governing gene transcription

A trio of groundbreaking publications from researchers in Northwestern University's Physical Sciences-Oncology Center (PS-OC) report important methodological advances that will enable a better understanding of how gene expression is regulated, both in normal cells and in cancer cells. This knowledge could lead to the development of more effective therapeutic agents to treat cancer patients.

2 Aug 2012

SPECT/CT with 99mTc-HMPAO-WBC can improve diagnosis of infectious endocarditis

When combined with standard diagnostic tests, functional imaging procedures have been shown to reduce the rate of misdiagnosed cases of infectious endocarditis. According to new research published in the August issue of The Journal of Nuclear Medicine, single photon emission computed tomography (SPECT)/computed tomography (CT) with 99mTc-hexamethylpropleneamine oxime-labeled white blood cells (99mTc-HMPAO-WBC) can improve the diagnosis of infectious endocarditis in hard-to-diagnose cases.

2 Aug 2012

'Global brain connectivity' explains 10% of variance in individual intelligence

When it comes to intelligence, what factors distinguish the brains of the exceptionally smart from those of average humans? As science has long suspected, overall brain size matters somewhat, accounting for about 6.7 percent of individual variation in intelligence. More recent research has pinpointed the brain's lateral prefrontal cortex, a region just behind the temple, as a critical hub for high-level mental processing, with activity levels there predicting another 5 percent of variation in individual intelligence.

2 Aug 2012

Researchers discover genetic process that can restore function to a CF defective protein

Researchers at the University of Iowa Carver College of Medicine have discovered a genetic process that can restore function to a defective protein, which is the most common cause of cystic fibrosis (CF).

2 Aug 2012

Roundup: Investors not shaken by accretive decision in Minn.; Conn. state abortion coverage conflicts with federal regs

Accretive Health got off pretty easy -- at least according to some on Wall Street. The $2.5 million that the Chicago-based firm must pay Minnesota Attorney General Lori Swanson is "relatively immaterial," wrote analysts from Credit Suisse on Tuesday, July 31, as they sized up the settlement announced between the parties.

2 Aug 2012

Diacetyl intensifies damaging effects of beta-amyloid proteins linked to Alzheimer's

A new study raises concern about chronic exposure of workers in industry to a food flavoring ingredient used to produce the distinctive buttery flavor and aroma of microwave popcorn, margarines, snack foods, candy, baked goods, pet foods and other products.

2 Aug 2012

$Cataract surgery reduces rate of fractures in older patients with vision loss$

Cataract surgery reduces rate of fractures in older patients with vision loss

A major study of Medicare beneficiaries shows that the risk of hip fractures was significantly reduced in patients who had had cataract surgery, compared to patients who did not undergo the procedure. Published in the August edition of the Journal of the American Medical Association (JAMA) the researchers believe their study is the first to demonstrate that cataract surgery reduces the rate of fractures in older patients with vision loss.

2 Aug 2012

High maternal choline intake may reduce risk of hypertension and diabetes in babies

New research from Cornell University indicates that pregnant women who increase choline intake in the third trimester of pregnancy may reduce the risk of the baby developing metabolic and chronic stress-related diseases like high blood pressure and diabetes later in life.

2 Aug 2012

CAP publishes revised version of molecular pathology checklist with dedicated section on NGS

The College of American Pathologists (CAP) published a revised version of its molecular pathology checklist with a dedicated section on next generation sequencing (NGS) as part of the new edition of the CAP Laboratory Accreditation Program checklists released July 31, 2012.

2 Aug 2012

Women with vulvodynia more likely to also have other chronic pain conditions

Millions of women suffer from unexplained vulvar pain so severe it can make intercourse, exercise and even sitting unbearable. New research now shows that women with this painful vaginal condition known as vulvodynia are two to three times more likely to also have one or more other chronic pain conditions, including irritable bowel syndrome, fibromyalgia (musculoskeletal pain) and interstitial cystitis (bladder pain).

2 Aug 2012

Researchers unlock genetic secrets of peripheral T-cell lymphomas

Researchers at Mayo Clinic have completed the world's first genome-wide sequencing analysis of peripheral T-cell lymphomas, unlocking the genetic secrets of this poorly understood and highly aggressive cancer of the immune system.

2 Aug 2012

MLK3 protein critical driver of breast cancer cell migration and invasion

By identifying a key protein that tells certain breast cancer cells when and how to move, researchers at Michigan State University hope to better understand the process by which breast cancer spreads, or metastasizes.

2 Aug 2012

Medical News

B-cell substances may play a role in MS progression

Financial viability of Social Security is in jeopardy because of outdated forecasting methods

In rare compromise, Hill leaders agree on temporary spending deal to keep government running through next March

Possible molecular link between circadian rhythm disturbances and increased inflammatory response

Scientists discover critical molecular switch that regulates autophagy

Report provides two distinct views of behavioral healthcare delivery

New FDA risk management plan aims to reduce opioid abuse in the U.S.

Medical staff struggle to spot problem drinkers unless they are already intoxicated

Three papers focus on nucleosomes and may help uncover the rules governing gene transcription

SPECT/CT with 99mTc-HMPAO-WBC can improve diagnosis of infectious endocarditis

'Global brain connectivity' explains 10% of variance in individual intelligence

Researchers discover genetic process that can restore function to a CF defective protein

Roundup: Investors not shaken by accretive decision in Minn.; Conn. state abortion coverage conflicts with federal regs

Diacetyl intensifies damaging effects of beta-amyloid proteins linked to Alzheimer's

Cataract surgery reduces rate of fractures in older patients with vision loss

High maternal choline intake may reduce risk of hypertension and diabetes in babies

CAP publishes revised version of molecular pathology checklist with dedicated section on NGS

Women with vulvodynia more likely to also have other chronic pain conditions

Researchers unlock genetic secrets of peripheral T-cell lymphomas

MLK3 protein critical driver of breast cancer cell migration and invasion

The importance of ketones from a clinical and medical perspective

How Programmable Nanobiology Could Drive the Fifth Industrial Revolution

Dr. Anthony Grice

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