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Roche files TnT-hs assay 510(k) submission with FDA for use on laboratory analyzers

Roche announced today that it has filed a 510(k) submission to the U.S. Food and Drug Administration (FDA) for a fully automated TnT-hs assay for use on Roche's full portfolio of laboratory analyzers.

From Roche Sequencing and Life Science 8 Jun 2012

Scientists discover new function for thrombospondin protein

Scientists have discovered a new function for a protein that protects cells during injury and could eventually translate into treatment for conditions ranging from cardiovascular disease to Alzheimer's.

8 Jun 2012

Ocular pulse amplitude reliable, safe screening test for carotid artery stenosis

A simple eye test may someday offer an effective way to identify patients who are at high risk for stroke, say researchers at the University of Zurich. They showed that a test called ocular pulse amplitude (OPA) can reliably detect carotid artery stenosis (CAS), a condition that clogs or blocks the arteries that feed the front part of the brain.

8 Jun 2012

MGH, HSG to conduct PBT2 clinical trial in Huntington's disease

The Huntington Study Group (HSG), under the leadership of Ray Dorsey, M.D. with Johns Hopkins Medical and Diana Rosas, M.D. with Massachusetts General Hospital, is conducting a clinical trial in Huntington's disease (HD) throughout the United States and Australia, "A randomized, double-blind, placebo-controlled, study to assess the safety and tolerability, and efficacy of PBT2 in patients with early to mid-stage Huntington's disease" comparing a 100 mg dose or 250 mg dose versus placebo.

8 Jun 2012

Bayer introduces Certegra Workstation

Bayer Radiology & Interventional announced the introduction of the Certegra Workstation, an informatics-driven, touch‐screen hub that enables time savings and improved patient care through a powerful suite of CT Contrast Dose Management applications and a new P3T 2.0 operating environment.

8 Jun 2012

Food allergies more prevalent among urban children

Children living in urban centers have a much higher prevalence of food allergies than those living in rural areas, according to a new study, which is the first to map children's food allergies by geographical location in the United States. In particular, kids in big cities are more than twice as likely to have peanut and shellfish allergies compared to rural communities.

8 Jun 2012

Anti-TNFs increase risk of shingles in patients with inflammatory rheumatic diseases

Patients with inflammatory rheumatic diseases (IRD) treated with anti-tumour necrosis factor medications (anti-TNFs) have a 75% greater risk of developing herpes zoster, or shingles, than patients treated with traditional disease modifying anti-rheumatic drugs (DMARDs), according to a meta-analysis presented today at EULAR 2012, the Annual Congress of the European League Against Rheumatism.

8 Jun 2012

UNAIDS Executive Director calls on African leaders to reduce 'triple dependency' on external sources of HIV drugs, commodities, technologies

"Delivering a speech at Wednesday's opening session of the 16th Conference of the West African Economic and Monetary Union (UEMOA), UNAIDS Executive Director Michel Sidibe congratulated leaders across the region for their personal commitment to the HIV response, specifically with regard to upholding human rights and protecting human capital," UNAIDS reports in an article on its website.

8 Jun 2012

GPs to get NHS Choices rating

GP practices in England are to be given a score out of 10 on the NHS Choices website.

7 Jun 2012

Women may need stronger lipid-lowering regimens

Women who are at high risk for cardiovascular disease are significantly less likely to achieve their lipid-lowering treatment goals than their male counterparts, show findings from a Chinese study.

7 Jun 2012

Aspirin linked to high bleeding rate in diabetes

Diabetes may be associated with an increased risk for major bleeding irrespective of aspirin use, researchers say.

7 Jun 2012

Aldosteronism linked to poor bone health

Primary aldosteronism is associated with low bone mass, increased prevalence of osteoporosis, and vertebral fractures, Italian research shows.

7 Jun 2012

Fluency therapy may improve stuttering in Down syndrome

Stuttering among children with Down syndrome may be substantially improved with fluency shaping therapy and parental contingency measures, leading to greater self-confidence, self-esteem, and school participation, suggest Canadian researchers.

7 Jun 2012

No benefits to polychemotherapy after surgery in gastric cancer

Findings from the ITACA-S trial suggest that a more intensive postoperative chemotherapy regimen does not improve outcomes over a less-intensive regimen after radical resection in patients with gastric cancer.

7 Jun 2012

Adjuvant chemoradiotherapy boosts esophageal cancer survival

Chemoradiotherapy significantly improves the outcome of patients undergoing surgery for cancer of the esophagus or esophagogastric junction and is well tolerated, suggests research in The New England Journal of Medicine.

7 Jun 2012

How to manage conflicts of interest in guideline development remains unclear

Setting an ethics framework could be useful to identify and manage conflicts of interest in the context of developing clinical practice guidelines, suggest researchers.

7 Jun 2012

Remote coaching helps improve diet and exercise habits

Study findings suggest that remote coaching supported by mobile technology and financial incentives could encourage healthier eating and physical activity habits in adults.

7 Jun 2012

Low pre-morbid IQ not associated with psychosis risk

The strong correlations currently observed between low IQ and risk for psychosis are most likely linked to the influence that psychosis onset has on cognitive functioning rather than a shared genetic background, suggest study findings.

7 Jun 2012

Pathophysiologic differences evident between schizophrenia, bipolar

Review findings reveal differences in the pathophysiology of bipolar disorder and schizophrenia, relating specifically to the medial temporal lobe and associated limbic regions.

7 Jun 2012

US emergency angioplasty guidelines ‘not sufficient’

The coordinated regional system of care for severe myocardial infarction in North Carolina, USA, should be established nationally, researchers say in Circulation.

7 Jun 2012