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Global mortality trends reveal convergence clubs and diverging patterns

Study analyzes global mortality trends from 1990 to 2030, identifying five convergence clubs of countries with similar mortality characteristics, revealing patterns of convergence and divergence in mortality and longevity.

18 Jan 2024

Plant protein in midlife boosts chances of healthy aging, study finds

A study in The American Journal of Clinical Nutrition reveals that higher dietary protein intake, especially plant protein, in middle adulthood significantly increases the likelihood of healthy aging, reducing chronic diseases and improving physical and mental health.

18 Jan 2024

Prior mycobacterium exposure remodels immune cells, impacting tuberculosis defense

Tuberculosis, caused by the bacterium Mycobacterium tuberculosis (Mtb) kills upwards of 1.6 million people a year, making it one of the leading causes of death by an infectious agent worldwide - and that number is only growing larger.

18 Jan 2024

Climate change linked to significant loss of life expectancy

The cost of climate change may be six months off the average human lifespan, according to a study published January 18, 2024, in the open-access journal PLOS Climate by Amit Roy from Shahjalal University of Science and Technology and The New School for Social Research, U.S.

18 Jan 2024

Wireless magnetogenetic approach could be used to treat motor dysfunction in people with Parkinson’s disease

Electrical deep brain stimulation (DBS) is a well-established method for treating disordered movement in Parkinson's disease.

18 Jan 2024

UNC scientists develop "smart" patch for precision drug delivery

University of North Carolina at Chapel Hill scientists created a new drug delivery system, called the Spatiotemporal On-Demand Patch (SOP), which can receive commands wirelessly from a smartphone or computer to schedule and trigger the release of drugs from individual microneedles.

18 Jan 2024

New structural insights pave the way for drug-resistant malaria therapies

Structural insights into a potent antimalarial drug candidate's interaction with the malaria parasite Plasmodium falciparum have paved the way for drug-resistant malaria therapies, according to a new study by researchers at Weill Cornell Medicine and Van Andel Institute.

18 Jan 2024

Oxford launches LEGACY03 trial to unravel age-related vaccine mysteries

Vaccines are the most effective way to prevent infectious diseases (NHS, 2023) however, people respond to them in different ways.

18 Jan 2024

Monell study: Unraveling the brain's wiring for fat and sugar cravings

Understanding why we overeat unhealthy foods has been a long-standing mystery. While we know food's strong power influences our choices, the precise circuitry in our brains behind this is unclear.

18 Jan 2024

Machine learning algorithm decodes mutations driving cancer treatment resistance

In a groundbreaking study published on January 18, 2024, in Cancer Discovery, scientists at University of California San Diego School of Medicine leveraged a machine learning algorithm to tackle one of the biggest challenges facing cancer researchers: predicting when cancer will resist chemotherapy.

18 Jan 2024

Exploring substance use and stress among first responders during COVID-19

Considerable attention has focused on burnout and mental health of physicians and nurses on the frontline during the COVID-19 pandemic.

18 Jan 2024

Uncovering the cellular roots of spinocerebellar ataxia type 6

Researchers from McGill University, led by Professor Alanna Watt of the Department of Biology, have identified previously unknown changes in brain cells affected by a neurological disease.

18 Jan 2024

MIT study reveals consistent oscillation patterns across brain cortex layers

Throughout the brain's cortex, neurons are arranged in six distinctive layers, which can be readily seen with a microscope.

18 Jan 2024

St. Jude announces $13 million investment to expand the understanding of G-protein coupled receptors

St. Jude Children's Research Hospital today announced a nearly $13 million investment toward a new research collaboration with scientists at Columbia University, Duke University and Stanford University to expand the understanding of G-protein coupled receptors (GPCR), which are vital proteins that impact human health and disease.

18 Jan 2024

ARCHA at Aston University secures £400,000 to recruit four PhD students for dementia research

The Aston Research Centre for Health in Ageing (ARCHA) at Aston University has received £400,000 in funding to recruit four PhD students for a dementia research programme.

18 Jan 2024

New insights into how prenatal exposure to organophosphate esters affects a child's growth

Organophosphate esters, commonly used as substitutes for brominated flame retardants, are increasingly present in various environmental media due to their use in consumer products.

18 Jan 2024

Cord blood-derived CAR NK cell therapy targeting CD19 shows promise for treating patients with B-cell malignancies

Researchers from The University of Texas MD Anderson Cancer Center reported promising results in a Phase I/II trial of 37 patients with relapsed or refractory B-cell malignancies who were treated with cord blood-derived chimeric antigen receptor (CAR) natural killer (NK) cell therapy targeting CD19.

18 Jan 2024