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New approach for production of tissue culture scaffolds in 3-D arrangements

Scientists at the University of California, San Diego have developed a new method for making scaffolds for culturing tissue in three-dimensional arrangements that mimic those in the body. This advance, published online in the journal Advanced Materials, allows the production of tissue culture scaffolds containing multiple structurally and chemically distinct layers using common laboratory reagents and materials.

10 Feb 2012

UC Riverside uncovers new insight into colon cancer

An international research team led by cell biologists at the University of California, Riverside has uncovered a new insight into colon cancer, the third leading cause of cancer-related deaths in the United States. The research provides potential new avenues for diagnosing and treating the disease.

10 Feb 2012

Farmers markets at medical centers may improve public health

Farmers markets at medical centers may contribute to greater wellness in surrounding communities while adding public health value to a market's mission, say Penn State College of Medicine researchers who have developed and evaluated a market created at Penn State Milton S. Hershey Medical Center.

10 Feb 2012

Study shows high cost of defensive orthopaedic care

In a first-ever national survey of orthopaedic surgeons, 96 percent said they have practiced defensive medicine - the ordering of tests, referrals to specialists and hospital admissions primarily to avoid liability and without significant benefit to patients - according to a new study presented today at the 2012 Annual Meeting of the American Academy of Orthopaedic Surgeons.

10 Feb 2012

New device offers fresh hope for patients with Motor Neurone Disease

Patients suffering from a devastating disease are being given fresh hope through an innovative trial being led by the Sheffield Institute for Translational Neuroscience (SITraN) and Sheffield Teaching Hospitals.

10 Feb 2012

Adaptive radiotherapy may benefit patients with head and neck cancer

Researchers led by a senior investigator at Hofstra-North Shore LIJ School of Medicine and The Feinstein Institute for Medical Research have released initial findings from a first-of-a-kind clinical trial in adaptive radiotherapy (ART) for head and neck cancer.

10 Feb 2012

Smith & Nephew introduces POLARCUP Dual Mobility Hip System

Smith & Nephew, the global medical technology business, is introducing the clinically proven POLARCUP Dual Mobility Hip System to orthopaedic surgeons in the US at this year's American Academy of Orthopaedic Surgeons (AAOS) annual meeting in San Francisco.

10 Feb 2012

Longer looks: Former Komen VP's new 'bona fides'; Alzheimer's definition changing?; Palin on her special needs child

Even if you put politics and ideology completely aside, Karen Handel had to resign from Susan G. Komen for the Cure. It's hard to think of the last time an employee did so much damage to such a respected brand in so little time. ... But while Komen will sustain long-term damage, Handel probably will be just fine. Yes, she's lost her position as Komen's vice president for public policy. But Handel has long had political aspirations, and she's now a right-wing cause célèbre.

10 Feb 2012

Ultrasound reliable alternative to X-rays for DDH screening in children

Developmental dislocation (dysplasia) of the hip (DDH) is a common congenital condition in which a child's upper thighbone is dislocated from the hip socket. The condition can be present at birth or develop during a child's first year of life. Plain radiography (X-rays) has long been the gold standard screening modality for this condition in 6-month-old children, despite concerns over exposing very young children to ionizing radiation.

10 Feb 2012

RI Hospital to study treatment that may prevent post-traumatic OA

Rhode Island Hospital has received a grant of $2.2 million from the United States Department of Defense to support a research study on a treatment that may prevent post-traumatic osteoarthritis, a common condition in men and women who suffer joint injuries to the knee and hip.

10 Feb 2012

Cancer-related fatigue linked to muscle mass and strength

Many patients with advanced cancer suffer from cachexia, a condition also called body-wasting or wasting syndrome, which causes significant weight loss, extreme fatigue and reduces quality of life.

10 Feb 2012

Single fibronectin injection can prevent chronic pain development after SCI

Chronic neuropathic pain following a spinal cord injury is common and very difficult to treat, but a new therapeutic strategy requiring a one-time injection into the spinal column has potential to improve patient outcomes.

9 Feb 2012

Two new NCCN guidelines for patients with colon and prostrate cancer

In order to provide people with cancer and their caregivers state-of-the-art treatment information in patient-friendly language, the National Comprehensive Cancer Network (NCCN) has developed two new publications: a new release of the NCCN Guidelines for Patients: Colon Cancer and an update to the NCCN Guidelines for Patients: Prostate Cancer.

9 Feb 2012

SSRIs may minimize risk of Sudden Unexpected Death in Epilepsy

A groundbreaking study published in Elsevier's Epilepsy & Behavior provides evidence in mouse model that drugs known as Selective Serotonin Reuptake Inhibitors (SSRIs; one category of antidepressants) may reduce the risk of Sudden Unexpected Death in Epilepsy (SUDEP).

9 Feb 2012

Ironwood prices public offering of 5,250,000 shares of common stock

Ironwood Pharmaceuticals, Inc. announced today the pricing of an underwritten public offering of 5,250,000 shares of its Class A common stock at a price of $15.09 per share to the public. All of the shares are being offered by Ironwood.

9 Feb 2012

Mylan's generic Doryx ANDA receives final FDA approval

Mylan Inc. today announced that its subsidiary Mylan Pharmaceuticals Inc. has received final approval from the U.S. Food and Drug Administration (FDA) for its Abbreviated New Drug Application (ANDA) for Doxycycline Hyclate Delayed-release (DR) Tablets USP, 150 mg. This product is the generic version of Mayne Pharma's Doryx, which is a tetracycline-class antimicrobial.

9 Feb 2012

Insurers shift more costs to patients; Washington state insurance commissioner wants to consider surpluses in rate increases

More insurers are shifting a growing amount of the cost of providing care to patients, Kaiser Health News reports. In other insurer news, UnitedHealth will overhaul how it pays doctors, and Washington's state insurance commissioner is asking for permission to consider insurer surpluses when mulling proposed insurance rate increases.

9 Feb 2012

FDA panel votes against Amgen’s Xgeva in prostate cancer

An FDA panel of oncologists has voted against a new use for Amgen's Xgeva in prostate cancer on Wednesday, saying the drug's ability to slow the spread of the disease did not translate into meaningful benefits for patients. Xgeva is already approved to prevent fractures in cancerous bones, and for osteoporosis, in a different formulation called Prolia.

9 Feb 2012

Parkinson’s disease gene - parkin explored: Study

Researchers at the University at Buffalo have discovered how mutations in the parkin gene cause Parkinson's disease, which afflicts at least 500,000 Americans and for which there is no cure. The results are published in the current issue of Nature Communications.

9 Feb 2012

Acid reducing drugs could raise risk of C. diff diarrhea

U.S. health regulators, the Food and Drugs Administration (FDA), have announced that ulcer drugs such as AstraZeneca Plc's blockbuster Nexium could increase the risk of Clostridium difficile-associated diarrhea (CDAD).

9 Feb 2012