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Top-line results from Noven's LDMP Phase 3 clinical study on menopausal VMS

Noven Pharmaceuticals, Inc., a wholly-owned subsidiary of Hisamitsu Pharmaceutical Co., Inc., today announced top-line results from the first of two planned Phase 3 clinical studies evaluating low-dose mesylate salt of paroxetine (LDMP, formerly referred to as Mesafem) for the treatment of vasomotor symptoms (VMS) associated with menopause.

23 Dec 2011

Senate, House at impasse on payroll tax timing

With no endgame in sight to prevent a looming payroll tax hike, President Obama and congressional leaders took turns trying to convince Americans that they were hard at work to save the tax break - even though Congress has essentially closed for the holidays. ... But finding consensus is easier said than done. Republicans and Democrats remain at odds over how to pay for the legislation.

23 Dec 2011

Surprising finding about implants used in hip replacement surgery

A new study, bringing together an interdisciplinary team of physicians and engineers from the United States and Germany, made a surprising finding about implants used in hip replacement surgery: Graphite carbon is a key element in the lubricating layer that forms on metal-on-metal hip implants. The lubricant has more in common with the lubrication of a combustion engine than that of a natural joint.

23 Dec 2011

Researchers evaluate role of Mediterranean diet ingredients in prevention of cell damage

The researchers evaluated the role of Mediterranean diet ingredients in the prevention and mitigation of cell damage.

23 Dec 2011

Faulty lipid metabolism may cause MS, says forensic anthropologist

An article to be published in the December 2011 issue of The Quarterly Review of Biology argues that multiple sclerosis, long viewed as primarily an autoimmune disease, is not actually a disease of the immune system.

23 Dec 2011

JCV, CDC announce publication of 'Update on HIV Diagnostic Testing Algorithms'

Elsevier's Journal of Clinical Virology in collaboration with the US Centers for Disease Control and Prevention (CDC) today announced the publication of a special supplement entitled 'Update on HIV Diagnostic Testing Algorithms'.

23 Dec 2011

Religious leaders should come together to ensure access to NTD medicines for world's poorest

Most of the world's neglected tropical diseases occur among populations that adhere to Islam, Catholicism, or Hinduism, an observation that "affords an opportunity to establish a unique interfaith dialogue among religious leaders" leading to global action, Peter Hotez, president of the Sabin Vaccine Institute, and Serap Aksoy, a professor at the Yale School of Public Health, write in a PLoS Neglected Tropical Diseases (NTD) editorial.

23 Dec 2011

$First study to explore impact of crowding on children with fracture-related pain$

First study to explore impact of crowding on children with fracture-related pain

Crowding in hospital emergency departments has led to a decrease in the timely and effective use of pain medication in children suffering acute long bone fractures, according to a new study by the University of Colorado School of Medicine.

23 Dec 2011

Fluoride has dramatic effects on bacteria inside the mouth

Regular use of fluoride-containing toothpaste and mouthwash has long been known to strengthen the enamel on teeth. But new research by Howard Hughes Medical Institute (HHMI) scientists finds that fluoride also has dramatic effects on bacteria inside the mouth -- including those that form plaque and can cause cavities.

23 Dec 2011

Scientists discover mechanism by which TNFα stimulates tumor formation

An inflammation-promoting protein triggers deactivation of a tumor-suppressor that usually blocks cancer formation via the NOTCH signaling pathway, a team of researchers led by scientists at The University of Texas MD Anderson Cancer Center reports today in Molecular Cell.

23 Dec 2011

Abbott commences Esprit drug eluting BVS trial in peripheral artery disease

Abbott today announced the initiation of ESPRIT I, a first-of-its-kind clinical trial in Europe evaluating the safety and performance of the novel Esprit drug eluting bioresorbable vascular scaffold (BVS) for the treatment of blockages in the superficial femoral arteries (SFA) and iliac arteries that have resulted in claudication.

23 Dec 2011

Health care issues leaving mark on presidential race

President Obama is busy touting his health law, while Mitt Romney argues that an individual mandate in Massachusetts is a "conservative" idea. In the meantime, the Associated Press examines Newt Gingrich's past support of the Children's Health Insurance Program.

23 Dec 2011

Changes in social structure, cultural practices can contribute to human evolution

Changes in social structure and cultural practices can also contribute to human evolution, according to a study that has recently been published in the journal Proceedings of the National Academy of Sciences (PNAS), contributed to by the lecturer Mireia Esparza and assistant Neus Martínez-Abadías, from the Anthropology Unit of the UB's Department of Animal Biology.

23 Dec 2011

Gladstone, Bristol-Myers Squibb to identify and validate novel targets in Alzheimer's

Bristol-Myers Squibb Company and the Gladstone Institutes today announced the formation of a discovery-based research collaboration to identify and validate novel targets in Alzheimer's disease.

23 Dec 2011

First picture of how specialized neurons are organized in hairy skin

Compared to our other senses, scientists don't know much about how our skin is wired for the sensation of touch. Now, research reported in the December 23rd issue of the journal Cell, a Cell Press publication, provides the first picture of how specialized neurons feel light touches, like a brush of movement or a vibration, are organized in hairy skin.

23 Dec 2011

Researchers identify previously unknown gene fusion event in lung cancer

Smoking is a well-known risk factor for lung cancer, but nearly 25% of all lung cancer patients have never smoked. In a study published online today in Genome Research, researchers have identified a previously unknown gene fusion event that could explain a significant proportion of lung cancer cases in never-smokers, and might serve as a target for new therapies.

23 Dec 2011

Russia will not use HIV spending to fund needle exchange, methadone therapy, Reuters reports

Though Russia is doubling its budget for HIV in 2012 over 2010 levels, "no money will go to such internationally recognized efforts as needle exchanges" and methadone replacement therapy, Reuters reports.

23 Dec 2011

ViroPharma to acquire Meritage

ViroPharma Incorporated today announced that it has entered into an exclusive option to acquire Meritage Pharma, Inc., a private company based in San Diego, CA focused on developing oral budesonide suspension (OBS) as a treatment for eosinophilic esophagitis (EoE), a chronic inflammatory disorder of the esophagus.

23 Dec 2011

Researchers identify molecules that can stimulate heart muscle regeneration

Damaged heart tissue is not known for having much inherent capacity for repair. But now, scientists are closing in on signals that may be able to coax the heart into producing replacement cardiac muscle cells. Using a zebrafish model system, researchers have identified a family of molecules that can stimulate stem cells to develop into beating heart muscle cells.

23 Dec 2011

Momenta, Baxter partner to develop and commercialize biosimilars

Baxter International Inc. and Momenta Pharmaceuticals, Inc. today announced that they have entered into a global collaboration to develop and commercialize follow-on biologic products, also known as biosimilars.

From Baxter International Inc. 23 Dec 2011