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Enrollment complete in two Anacor's tavaborole Phase 3 trials on onychomycosis

Anacor Pharmaceuticals announced today that it has completed the enrollment of approximately 600 patients in the second of its two Phase 3 trials of tavaborole, a topical anti-fungal product candidate for the treatment of onychomycosis, a fungal infection of the nail and nail bed that affects approximately 35 million people in the United States.

23 Dec 2011

Roundup: Texas members oppose state's MLR waiver; Calif.'s disability case takes unusual turn

If you want to know what a Tea Party America might look like, there is no place like Kansas. In the past year, three state agencies have been abolished and 2,050 jobs have been cut. Funding for schools, social services and the arts have been slashed. The new Republican governor rejected a $31.5 million federal grant for a new health-insurance exchange because he opposes President Obama's health-care law. And that's just the small stuff.

23 Dec 2011

Inhibition of necroptosis protects mice from lethal SIRS

Sepsis, a form of systemic inflammation, is the leading cause of death in critically ill patients. Sepsis is linked with massive cell death; however, the specific mechanisms involved in the lethality of sepsis are unclear. Now, a new study published by Cell Press in the December 23rd issue of the journal Immunity finds that inhibition of a specific cell death pathway called "necroptosis" protected mice from lethal inflammation.

23 Dec 2011

Oak Pharmaceuticals acquires three Lundbeck hospital-based injectables

Akorn, Inc., a niche generic pharmaceutical company, today announced that its wholly-owned subsidiary, Oak Pharmaceuticals, has acquired three off-patent, branded, hospital-based injectables from the US subsidiary of H. Lundbeck A/S.

23 Dec 2011

ECMC network receives £35M grants for cancer medicine research

The Experimental Cancer Medicine Centres (ECMC) network, which runs UK clinical studies of the newest cancer treatments, has been awarded a second wave of £35M funding for the next five years.

23 Dec 2011

Researchers develop CAD-type tools to engineer RNA control systems

The computer assisted design (CAD) tools that made it possible to fabricate integrated circuits with millions of transistors may soon be coming to the biological sciences. Researchers at the U.S. Department of Energy (DOE)'s Joint BioEnergy Institute (JBEI) have developed CAD-type models and simulations for RNA molecules that make it possible to engineer biological components or "RNA devices" for controlling genetic expression in microbes.

23 Dec 2011

Longer looks: Manufacturing killer flu; The ironies of the individual mandate; When the elderly refuse help

In experiments conducted at the University of Wisconsin in Madison and Erasmus University in Rotterdam, the Netherlands, researchers engineered a strain of H5N1. … The next logical step would be for the researchers to publish studies in major scientific journals, describing the newly created flu, including its genetic makeup.

23 Dec 2011

Link between respiratory illness and PSTD among WTC first responders

More than 10 years after 9/11, when thousands of rescue and recovery workers descended on the area surrounding the World Trade Center in the wake of the terrorist attacks, a research team led by Benjamin J. Luft, M.D., the Edmund D. Pellegrino Professor of Medicine, and Medical Director of Stony Brook's World Trade Center Health Program, and Evelyn Bromet, Ph.D., Distinguished Professor, Departments of Psychiatry and Behavioral Science, and Preventive Medicine, Stony Brook University School of Medicine, has published results of a study examining the relationship between the two signature health problems among WTC first responders—respiratory illness and post-traumatic stress disorder.

23 Dec 2011

Science journal names UNC HIV prevention study as 2011 Breakthrough of the Year

The HIV Prevention Trials Network 052 study, led by Myron S. Cohen, MD of the University of North Carolina at Chapel Hill, has been named the 2011 Breakthrough of the Year by the journal Science.

23 Dec 2011

Botox can have unsuspected 'systemic' effects on muscles

Botulinum neurotoxin type A—better known as Botox—has previously unsuspected 'systemic' effects on muscles other than the ones it's injected into, reports a study in the January issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society.

23 Dec 2011

ThromboGenics submits ocriplasmin BLA with FDA to treat symptomatic VMA

ThromboGenics NV, a biopharmaceutical company focused on developing innovative ophthalmic medicines, today announces that it has submitted a Biologics License Application (BLA) with the U.S. Food and Drug Administration (FDA) for ocriplasmin Intravitreal Injection, 2.5 mg/mL, for the treatment of symptomatic VMA including macular hole.

23 Dec 2011

ASCs need to develop policies for management of malignant hyperthermia

As the number of surgical procedures performed outside hospitals continues to increase, ambulatory surgical centers (ASCs) need to develop policies for managing malignant hyperthermia—a rare but serious reaction to anesthetics, according to an expert panel report in the January issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society.

23 Dec 2011

D12-PGJ3 compound can cure leukemia

A compound produced from fish oil that appears to target leukemia stem cells could lead to a cure for the disease, according to Penn State researchers. The compound -- delta-12-protaglandin J3, or D12-PGJ3 -- targeted and killed the stem cells of chronic myelogenous leukemia, or CML, in mice, said Sandeep Prabhu, associate professor of immunology and molecular toxicology in the Department of Veterinary and Medical Sciences.

23 Dec 2011

EpiCept receives FDA approval to commence AmiKet Phase III trial for CIPN

EpiCept Corporation today announced that at a meeting earlier this week with the U.S. Food and Drug Administration (FDA), the Company was granted permission to initiate immediately the Phase III clinical development of AmiKet.

23 Dec 2011

Tunstall completes acquisition of AMAC

Following the announcement on 22 September 2011, American Medical Alert Corp, a leading provider of remote health monitoring and 24/7 communication services that enhance care, accelerate response times, improve operational effectiveness and deliver sustainable patient services, is pleased to announce today the completion of its acquisition by Tunstall Healthcare Group, a leading telehealth and telecare provider based in the UK.

23 Dec 2011

Ohio law prohibits abortion coverage by insurers in state exchanges; Pa. measure would step up abortion clinic regulation

Ohio Governor John Kasich on Wednesday signed a law that would prohibit abortion coverage from the state insurance exchange Ohio must create under the federal health care law. ... The law bans Ohio citizens from being able to purchase insurance through the exchange that includes abortion coverage, even if they pay for it with their own money, said Kellie Copeland, executive director of NARAL Pro-Choice Ohio, who criticized the bill.

23 Dec 2011

FDA clears OptiMedica's Catalys Precision Laser System

Global ophthalmic company OptiMedica Corp. has announced the U.S. Food and Drug Administration (FDA) 510(k) market clearance of its Catalys Precision Laser System, a next generation laser cataract surgery system that brings unequaled precision and accuracy and a markedly streamlined workflow to the laser cataract procedure.

22 Dec 2011

Hand washing tips to prevent illness and spreading germs

With holiday gatherings, New Year celebrations, and constant travelling, hand washing is one of the most important ways to prevent getting sick and spreading germs. Many illnesses, including the common cold, are spread by not washing hands properly with soap and water. According to statistics from the National Library of Medicine, the common cold accounts for approximately 22 million missed days of school and 20 million absences from work.

22 Dec 2011

Consistent evidence that HRT use associated with breast cancer

McMaster University researchers have found consistent evidence that use of hormone replacement therapy (HRT) is associated with breast cancer globally.

22 Dec 2011

Fetal heart rate monitor may improve infant's health

Despite the numerous medical advances that happen every day, the infant mortality rate in the United States is still higher than most European countries. While experts believe this is closely linked to the growing rate of pre-term births, researchers are committed to finding ways to make labor and delivery safer. Northwestern Medicine- researchers are examining a new device that may support improved newborn health at delivery through closer monitoring of infant oxygen use during labor.

22 Dec 2011