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TAVR demonstrates lower risk and improved outcomes compared to SAVR in low-risk patients

Transcatheter aortic valve replacement (TAVR) was found to bring no increased risks and was associated with substantial decreased rates of death or stroke at one year in low-risk patients, compared with surgical aortic valve replacement (SAVR), according to findings presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Chronic low-level inflammation may be a contributor to both depression and heart disease

Coronary artery disease and major depression may be genetically linked via inflammatory pathways to an increased risk for cardiomyopathy, a degenerative heart muscle disease, researchers at Vanderbilt University Medical Center and Massachusetts General Hospital have found.

8 Apr 2024

Personalized anti-tumor vaccine enhances immunotherapy for liver cancer

Adding a personalized anti-tumor vaccine to standard immunotherapy is safe and about twice as likely to shrink cancer as standard immunotherapy alone for patients with hepatocellular carcinoma, the most common type of liver cancer, according to a clinical trial led by researchers at the Johns Hopkins Kimmel Cancer Center and its Convergence Institute.

8 Apr 2024

Nerve ablation's varied outcomes in high blood pressure treatment

A new system that uses dehydrated alcohol to deactivate certain nerves surrounding the kidneys' arteries in order to control high blood pressure met its primary endpoint—lowering blood pressure at three months as measured with a 24-hour ambulatory systolic blood pressure monitor—in a pivotal phase 3 trial presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Preventive PCI reduces cardiac event risks in patients with high-risk plaque

People with a buildup of fatty atherosclerotic plaque in the heart's arteries considered at risk of rupturing were far less likely to suffer a serious cardiac event if they underwent percutaneous coronary intervention (PCI), a procedure to open blocked arteries, compared with those who took medications alone but did not undergo PCI, according to research presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

IVUS guidance improves angioplasty success rates in patients with peripheral artery disease

One-year success rates from angioplasty procedures to open clogged arteries in the legs were significantly higher among patients whose procedures were guided by intravascular ultrasound (IVUS) alongside angiography compared with those whose procedures were guided by angiography alone, in a study presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Revolutionary therapeutic shows promise for pancreatic cancer treatment

A new type of investigational therapeutic in development for pancreatic cancer has shown unprecedented tumor-fighting abilities in preclinical models of the disease, suggesting it has the potential to offer novel treatment options for nearly all pancreatic tumors, a comprehensive study has found.

8 Apr 2024

Study uncovers how consensual touch can benefit a person's physical and mental wellbeing

Through a large-scale analysis, researchers at the Netherlands Institute for Neuroscience have uncovered the ways in which consensual touch can benefit a person's physical and mental wellbeing.

8 Apr 2024

Ninerafaxstat shows good tolerability and safety in nonobstructive HCM patients

The investigational drug ninerafaxstat showed a good tolerability and safety profile, along with evidence of improvements in symptoms and exercise capacity among people with nonobstructive hypertrophic cardiomyopathy (HCM), according to results of a 12-week phase 2 trial presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

DEPOSITION trial evaluates the use of topical tranexamic acid during heart surgery

Administering tranexamic acid (TxA), a drug used to reduce bleeding during heart surgery, topically rather than intravenously did not meet its primary endpoint of reducing seizures and was stopped early due to an increased risk of bleeding events, according to research presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Treating early-stage heart failure in diabetic patients: Insights from ARISE-HF trial

One of the first studies to attempt to treat early-stage heart failure in patients with Type 2 diabetes did not meet its primary endpoint, but a preplanned subgroup analysis found a statistically significant effect of treatment in patients who were not taking SGLT2 inhibitors or GLP-1 RAs, which are antidiabetic medications that also have benefits for the heart.

8 Apr 2024

Preventive ventricular tachycardia ablation cuts down ICD shocks and hospitalizations

The first randomized trial to investigate preventive ablation of a potential arrhythmogenic substrate associated with coronary chronic total occlusion (CTO) in patients at high risk of ventricular arrhythmias (VAs) reduces the risk of appropriate implantable cardioverter-defibrillator (ICD) therapy and unplanned hospitalization in patients with no previously recorded VAs.

8 Apr 2024

Novel therapeutic approach identified for overcoming resistance in B-cell leukemia

Despite having an overall survival rate of 94%, B-cell acute lymphoblastic leukemia (B-ALL), the most common childhood cancer, can prove challenging to treat, with survival among relapsed or resistant cases falling between 30-50%.

8 Apr 2024

Study finds racial disparities in chemical sedation rates for psychiatric patients in the EDs

Black patients presenting at Emergency Departments (EDs) across the country with psychiatric complaints are 63 percent more likely to be chemically sedated than their white counterparts.

8 Apr 2024

ACE inhibitors show no benefit in reducing chemotherapy-induced heart damage

Patients who took an angiotensin-converting enzyme (ACE) inhibitor while undergoing cancer treatment with high-dose anthracycline chemotherapy did not show any difference in troponin T levels, a biomarker associated with heart damage, at one month after their last chemotherapy dose compared with those who did not take an ACE inhibitor, according to a study presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Poor oral health linked to negative long-term systemic health outcomes

Those who report having poor oral health are as likely to have negative long-term systemic health outcomes as those previously diagnosed with periodontal disease, or gum disease, according to a new Tufts University School of Dental Medicine study published in The Journal of the American Dental Association.

8 Apr 2024

First-ever guidelines developed to help build a child's tolerance to common food allergens

Researchers with McMaster University have crafted the first-ever guidelines to help prepare families who plan to build their child's tolerance to common food allergens.

8 Apr 2024

Immersive VR may be a useful non-medication strategy to improve cancer pain

A 10-minute virtual reality (VR) session significantly lessened pain in hospitalized patients with cancer in a recent clinical trial published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society. Even a day later, participants experienced sustained benefits.

8 Apr 2024

Depression impacts survival rates and quality of life for women with breast cancer

A new study presented at the European Psychiatric Association Congress 2024 sheds light on the significant impact of depression on the survival rates and quality of life for women diagnosed with breast cancer.

8 Apr 2024

Study shows association between low youth cardiorespiratory fitness and adulthood decreased work ability

A study from the University of Jyväskylä confirms the concerns raised in the public domain about how young people's decreased fitness may affect their future work ability.

8 Apr 2024

Medical News

TAVR demonstrates lower risk and improved outcomes compared to SAVR in low-risk patients

Chronic low-level inflammation may be a contributor to both depression and heart disease

Personalized anti-tumor vaccine enhances immunotherapy for liver cancer

Nerve ablation's varied outcomes in high blood pressure treatment

Preventive PCI reduces cardiac event risks in patients with high-risk plaque

IVUS guidance improves angioplasty success rates in patients with peripheral artery disease

Revolutionary therapeutic shows promise for pancreatic cancer treatment

Study uncovers how consensual touch can benefit a person's physical and mental wellbeing

Ninerafaxstat shows good tolerability and safety in nonobstructive HCM patients

DEPOSITION trial evaluates the use of topical tranexamic acid during heart surgery

Treating early-stage heart failure in diabetic patients: Insights from ARISE-HF trial

Preventive ventricular tachycardia ablation cuts down ICD shocks and hospitalizations

Novel therapeutic approach identified for overcoming resistance in B-cell leukemia

Study finds racial disparities in chemical sedation rates for psychiatric patients in the EDs

ACE inhibitors show no benefit in reducing chemotherapy-induced heart damage

Poor oral health linked to negative long-term systemic health outcomes

First-ever guidelines developed to help build a child's tolerance to common food allergens

Immersive VR may be a useful non-medication strategy to improve cancer pain

Depression impacts survival rates and quality of life for women with breast cancer

Study shows association between low youth cardiorespiratory fitness and adulthood decreased work ability

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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