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NIH awards $15.5 million to expand clinical trials inclusion for nursing home residents

A team led by research scientists from the Indiana University School of Medicine and Regenstrief Institute has received funding expected to total $15.5 million from the National Institutes of Health's National Institute on Aging to establish a national network structure to include more nursing home residents in clinical trials.

29 Aug 2024

Distinct waves of T cells generated by each dose of combination immunotherapy

A new tool for monitoring immune health patterns over time has revealed how a pair of checkpoint inhibitor therapies works together to recruit new cancer-fighting T cells with every infusion.

29 Aug 2024

Study finds diabetes linked to accelerated brain aging, but healthy habits can help

The study links diabetes to accelerated brain aging, highlighting lifestyle factors that could mitigate risks, especially for males with cardiometabolic issues.

29 Aug 2024

Study reveals key role of A20 protein in controlling inflammation in liver disease

Many individuals worldwide suffer from chronic liver disease (CLD), which poses significant concerns for its tendency to lead to hepatocellular carcinoma or liver failure. CLD is characterized by inflammation and fibrosis.

29 Aug 2024

Cannabis and hallucinogen use stayed at historically high among adults in 2023

The percentages of adults using cannabis and hallucinogens over the past year stayed at historically high levels in 2023, according to the latest findings from the University of Michigan’s Monitoring the Future survey.

29 Aug 2024

Routine lipoprotein(a) testing recommended for all adults

Heart experts say that everyone should have their levels of lipoprotein (a) (Lp(a) measured routinely at least once in life, following research from one of the most populous EU countries, Poland, that shows how common high levels of Lp(a) are in the general population.

29 Aug 2024

Mapping DNA’s hidden knot-like structures may revolutionize disease treatment

Innovative study of DNA's hidden structures may open up new approaches for treatment and diagnosis of diseases, including cancer.

29 Aug 2024

Endometriosis linked to increased risk of heart attack and stroke in women

According to research presented at ESC Congress 2024,1 women with endometriosis have a 20% greater risk of significant cardiac outcomes compared with women without endometriosis.

29 Aug 2024

Smoking cessation reduces major cardiovascular events by almost half, study finds

According to research presented today at ESC Congress 2024, patients with stable coronary artery disease who quit smoking at any timepoint after their diagnosis reduced their risk of a major event by almost 50%.

29 Aug 2024

Girls with mental illness less likely to receive HPV vaccination

Girls with mental illness or neurodevelopmental conditions are less likely than their peers to be vaccinated with the HPV vaccine that protects against future cervical cancer.

29 Aug 2024

Weekend sleep could lower heart disease risk by 20%

The demands of the working week, often influenced by school or work schedules, can lead to sleep disruption and deprivation.

29 Aug 2024

Study explores link between prostate cancer treatment and Alzheimer’s disease

Researchers at the Medical College of Georgia at Augusta University are searching for a better way to understand why many men with prostate cancer end up with Alzheimer's disease, and whether it's the standard hormone therapy treatment or an overactive immune response that actually contributes to the problem.

29 Aug 2024

Electrophysiological analysis of brain network for augmented recognition of driving distractions

A research paper by scientists at Beijing Jiaotong University proposed an electrophysiological analysis-based brain network method for the augmented recognition of diﬀerent types of distractions during driving.

29 Aug 2024

Georgia Tech study unveils music's role in modulating memory and emotion

The soundtrack of this story begins with a vaguely recognizable and pleasant groove. But if I stop writing and just listen for a second, the music reveals itself completely.

29 Aug 2024

Preventing the spread of superbugs in aged care facilities

There's an urgent need for more careful antibiotic management to protect older people living in residential aged care from the dangerous spread of antibiotic-resistant bacteria or 'superbugs', researchers from Flinders University and SAHMRI warn.

29 Aug 2024

Understanding the mechanisms of cardiac fibrosis

The article explores the role of the m6A reader YTHDF1 in cardiac fibrosis, a condition characterized by the excessive accumulation of extracellular matrix proteins, leading to the stiffening of the heart and impaired function. Cardiac fibrosis is a common pathological process in various cardiovascular diseases, including hypertension, myocardial infarction, and heart failure.

29 Aug 2024

New insights into AD pathogenesis and treatment

The main text of the study details the experiments conducted to understand the role of IL-24 in AD-like conditions. It describes the methods used, including single-cell RNA sequencing, and the animal models employed to mimic AD. The findings indicate that MRSA infection leads to increased IL-24 in keratinocytes, which in turn heightens type 2 immune responses and worsens AD symptoms.

29 Aug 2024

Addressing HPV vaccination disparities in girls with mental health conditions

Girls with mental illness or neurodevelopmental conditions are less likely than their peers to be vaccinated with the HPV vaccine that protects against future cervical cancer. This is according to a new registry study from Karolinska Institutet in Sweden published in The Lancet Public Health.

29 Aug 2024

North Carolina's residential opioid treatment services lack evidence-based approaches

A new study of organizations that claim to provide residential opioid substance use services in North Carolina found that only 12% of the organizations were licensed by the state to provide residential substance use treatment. What's more, only about a quarter of the organizations even allowed patients to access the only treatment for opioid use disorder proven to reduce overdose deaths.

29 Aug 2024

Study reveals the role of blood clotting in COVID-19

In a study that reshapes what we know about COVID-19 and its most perplexing symptoms, scientists have discovered that the blood coagulation protein fibrin causes the unusual clotting and inflammation that have become hallmarks of the disease, while also suppressing the body's ability to clear the virus.

29 Aug 2024