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Disorder in degradation of proteins and other macromolecules in cells leads to serious diseases

The degradation of proteins and other macromolecules in cells is vital to survival. Disruption of this process can result in serious disease. The research group of Professor Thomas Jentsch (Leibniz Institute for Molecular Pharmacology, FMP/ Max Delbr-ck Center for Molecular Medicine, MDC, Berlin-Buch) has now succeeded in identifying an essential cellular process necessary for the transport and degradation of macromolecules in endosomes and lysosomes, respectively.

16 Jun 2010

ISB, GIND collaborate on whole-genome sequencing to identify drug targets for Huntington's Disease

The Institute for Systems Biology (ISB) of Seattle, WA, is collaborating with the Gladstone Institute of Neurological Disease (GIND) and its Taube-Koret Center for Huntington's Disease Research to use whole-genome sequencing to identify genes and novel drug targets related to the onset and progression of Huntington's disease (HD). The research team, led by GIND associate director and senior investigator Steven Finkbeiner, MD, PhD, will also use induced pluripotent stem (iPS) cells from patients with HD to screen for drugs that might delay, prevent, or even reverse this devastating condition.

16 Jun 2010

Supreme Court to hear case on overcrowding and medical needs of Calif. prisoners; Ohio state employees have unusual situation covering adult children

Agreeing to hear an appeal from Gov. Arnold Schwarzenegger, the U.S. Supreme Court said Monday it will decide whether the state can be forced to release 46,000 inmates — more than one-fourth of its prison population — to relieve overcrowding. The justices said they would hear the case in the fall and rule early next year.

16 Jun 2010

Topical NSAIDs are safe and effective for acute pain: Researchers

Gels, creams and sprays containing painkillers such as ibuprofen, diclofenac, ketoprofen, and piroxicam are safe and effective treatments for local pain, according to Cochrane Researchers. A new systematic review they have conducted shows that topical non-steroidal anti-inflammatory drugs are more effective than placebos for treating short-term pain and have few side effects.

16 Jun 2010

Bill Gates, Carlos Slim, Spanish government announce $150M for health projects in Central America, Mexico

Bill Gates, co-founder of the Bill & Melinda Gates Foundation, and Carlos Slim, the "Mexican telecom magnate" and founder of the Carlos Slim Institute, announced Monday that they would work with Spain on a $150 million health initiative for people in Central America and Mexico, Agence France-Presse reports.

16 Jun 2010

UT Southwestern head and neck cancer surgeons perform area's first transoral robotic surgery

Head and neck cancer surgeons at UT Southwestern Medical Center performed the area's first transoral robotic surgery (TORS), a recently approved minimally invasive no-scar procedure to remove tumors in the throat.

16 Jun 2010

Sapient Discovery, Helicon Therapeutics enter structural biology collaboration

Sapient Discovery, LLC., a structure-guided drug discovery company, announced today that it has entered into a research collaboration agreement with the Helicon Therapeutics, Inc., a San Diego based pharmaceutical company. Under the terms of the agreement, Sapient Discovery will apply its proprietary structural biology platform and expertise to determine the three-dimensional structures for targets of interest to Helicon Therapeutics, Inc.

16 Jun 2010

Vitamin D may help reduce incidence, severity of viral respiratory tract infections: Study

Vitamin D may help reduce the incidence and severity of viral respiratory tract infections including influenza, according to a new study conducted by investigators at Greenwich Hospital and Yale University School of Medicine.

16 Jun 2010

Washington Post examines trial in Africa of long-acting vaginal ring for HIV prevention

"The first test of a long-acting vaginal ring loaded with an HIV-preventing drug has begun enrolling women in southern Africa," the Washington Post reports. The study, according to the newspaper, marks the 15th trial led by the nonprofit group, International Partnership for Microbicides, which "has helped lead the search for a discreet, woman-controlled means of protection" against the virus.

16 Jun 2010

Most elite medical schools rank low on 'social mission'

Kaiser Health News staff writer Jenny Gold reports: "A new study is turning the traditional medical school ranking list on its head.

16 Jun 2010

Eating Mediterranean-style diet reduces heart disease risk: Research

A study of twins shows that even with genes that put them at higher risk of cardiovascular disease, eating a Mediterranean-style diet can improve heart function, according to research reported in Circulation: Cardiovascular Quality and Outcomes, an American Heart Association journal.

16 Jun 2010

Florida Advisory Council on Radiation Protection endorses ASTRO's Target Safely patient protection plan

Through a unanimous decision, the Florida Advisory Council on Radiation Protection has endorsed Target Safely, the American Society for Radiation Oncology's (ASTRO) patient protection plan.

16 Jun 2010

Course on cancer rehabilitation for nurses and other health professionals

Nurses and other health professionals will soon be able to take a dedicated course on cancer rehabilitation at Swansea University. The master's module in cancer rehabilitation is being launched to help the training of health and social care staff.

16 Jun 2010

NIH awards Geisinger $1.8M grant for study of nuclear ErbB3 protein

A new five-year, $1.8 million National Institutes of Health grant awarded to staff scientist Nikolaos Tapinos, M.D., Ph.D., of Geisinger's Sigfried and Janet Weis Center for Research will be used to study the role of nuclear ErbB3 protein during development of the nervous system and in response to nerve injury.

16 Jun 2010

Sanofi-aventis signs definitive agreement to acquire assets of Canderm

Sanofi-aventis announced today that it has entered into a definitive agreement under which an affiliate of sanofi-aventis Canada Inc. is to acquire the assets of Canderm Pharma Inc., a privately-held leading Canadian skin care company. This agreement is consistent with the sanofi-aventis Group's global strategy to expand its consumer health care growth platform and follows on the heels of the Group's acquisition of the North American CHC company Chattem Inc. in March 2010.

16 Jun 2010

Cancer overtreatment raises concern; Physicians tend to use new technology even before solid evidence backs it

The Associated Press/Arizona Republic: "It's an unthinkable notion for a generation raised on the message that early cancer detection saves lives, but specialists say more tumors actually are being found too early. That is raising uncomfortable questions about how aggressively to treat early growths -- in some cases, even how aggressively to test -- along with a push for more of the informed-choice programs.

16 Jun 2010

Reid takes steps toward final vote on 'extenders' package after turning down GOP alternative

Senate Majority Leader Harry Reid filed a motion Monday to stop debate on a bill that includes $140 billion in spending on items such as extended unemployment benefits, enhanced Medicaid payments to states and a fix to keep Medicare reimbursements to doctors from being trimmed. The move suggests Reid thinks he is close to having the votes for passage.

16 Jun 2010

New cancer research centre launched in Edinburgh

Edinburgh today (Wednesday) becomes the next link in a unique chain of Cancer Research UK Centres that are being launched across the UK.

16 Jun 2010

Prostate cancer deaths are expected to jump 17%: 2010 statistics

Prostate cancer deaths are expected to jump 17 percent this year, according to estimates based on National Cancer Institute data. The alarming 2010 statistics, just prior to Father's Day, has ZERO – The Project to End Prostate Cancer urging families to encourage Dad to get tested for the disease this Father's Day because prostate cancer is the second leading cancer among American men.

16 Jun 2010

Final results from Visudyne Phase IIIb DENALI study presented at World Ophthalmology Congress

QLT Inc. today announced that final results from the Novartis-sponsored Phase IIIb DENALI study were presented on June 8, 2010 during the World Ophthalmology Congress in Berlin. DENALI was a 24-month randomized, double-masked, multicenter trial in patients with subfoveal choroidal neovascularization secondary to wet age-related macular degeneration (all lesion types).

16 Jun 2010

Medical News

Disorder in degradation of proteins and other macromolecules in cells leads to serious diseases

ISB, GIND collaborate on whole-genome sequencing to identify drug targets for Huntington's Disease

Supreme Court to hear case on overcrowding and medical needs of Calif. prisoners; Ohio state employees have unusual situation covering adult children

Topical NSAIDs are safe and effective for acute pain: Researchers

Bill Gates, Carlos Slim, Spanish government announce $150M for health projects in Central America, Mexico

UT Southwestern head and neck cancer surgeons perform area's first transoral robotic surgery

Sapient Discovery, Helicon Therapeutics enter structural biology collaboration

Vitamin D may help reduce incidence, severity of viral respiratory tract infections: Study

Washington Post examines trial in Africa of long-acting vaginal ring for HIV prevention

Most elite medical schools rank low on 'social mission'

Eating Mediterranean-style diet reduces heart disease risk: Research

Florida Advisory Council on Radiation Protection endorses ASTRO's Target Safely patient protection plan

Course on cancer rehabilitation for nurses and other health professionals

NIH awards Geisinger $1.8M grant for study of nuclear ErbB3 protein

Sanofi-aventis signs definitive agreement to acquire assets of Canderm

Cancer overtreatment raises concern; Physicians tend to use new technology even before solid evidence backs it

Reid takes steps toward final vote on 'extenders' package after turning down GOP alternative

New cancer research centre launched in Edinburgh

Prostate cancer deaths are expected to jump 17%: 2010 statistics

Final results from Visudyne Phase IIIb DENALI study presented at World Ophthalmology Congress

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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