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Addition of dasatinib to standard chemo cocktail may enhance effect in certain ovarian cancers

The addition of a chemotherapeutic drug for leukemia to a standard regimen of two other chemotherapy drugs appears to enhance the response of certain ovarian cancers to treatment, according to a pre-clinical study led by researchers in the Duke Comprehensive Cancer Center.

20 Apr 2009

A potential therapeutic target for gastric cancer

Gastric cancer (GC) is the fourth most common malignancy and the second most frequent cause of cancer-related death in the world.

20 Apr 2009

Novel method of isolating high quality RNA from Kupffer cells

Kupffer cells, resident tissue macrophages that line the liver sinusoids, play a key role in modulating inflammation in a number of experimental models of liver injury.

20 Apr 2009

Young women on the pill suffer impaired muscle gains from weight lifting

According to American researchers women who take oral contraceptives (OC) could find any muscle which might be gained from resistance exercise training is impaired.

20 Apr 2009

Safety of bird flu drug Tamiflu in children questioned

A prominent Japanese researcher reporting on the bird flu drug Tamiflu says the drug may not be safe for children.

20 Apr 2009

Cooked tomatoes may be healthier than raw ones

According to scientists in New Zealand, eating a raw tomato may not be the best way to access it s healthy antioxidants - they say a mere 4% of the antioxidant lycopene is released from raw tomatoes.

20 Apr 2009

Women who wear veils risk vitamin D deficiency

A study by Australian scientists has found that women who wear veils for religious or cultural reasons may not be getting enough vitamin D.

20 Apr 2009

Children as young as five with life threatening anorexia

New research by Australian experts has revealed that children as young as five are being treated for eating disorders - the researchers say in some cases the eating disorder has reached the stage that forced feeding becomes necessary in order to save their lives.

20 Apr 2009

Jet lag disrupts sleep by throwing two neural centers out of sync

New research by scientists in the U.S. has revealed that the disrupted sleep which results from jet lag and shift work occurs in two separate but linked groups of neurons below the hypothalamus at the base of the brain.

19 Apr 2009

Scientists uncover secrets of salmonella's stealth attack

A single crafty protein allows the deadly bacterium Salmonella enterica to both invade cells lining the intestine and hijack cellular functions to avoid destruction, Yale researchers report in the April 17 issue of the journal Cell.

16 Apr 2009

When every photon counts: unusual cell nuclei help nocturnal animals see better

The eyes of nocturnal mammals have very large numbers of highly-sensitive rod photoreceptors (the cell type responsible for night vision).

16 Apr 2009

Vion Pharmaceuticals' NDA for Onrigin accepted for FDA review

Vion Pharmaceuticals, Inc. has announced that the New Drug Application (NDA) for its lead oncology therapeutic Onrigin (laromustine) Injection has been accepted for review by the U.S. Food and Drug Administration (FDA).

16 Apr 2009

Vegan nuns found to have same bone density as non-vegans

A study comparing the bone health of 105 post-menopausal vegan Buddhist nuns and 105 non-vegetarian women, matched in every other physical respect, has produced a surprising result.

16 Apr 2009

DNA biosynthesis discovery could lead to better antibiotics

Combating several human pathogens, including some biological warfare agents, may one day become a bit easier thanks to research reported by a University of Iowa chemist and his colleagues in the April 16 issue of the journal Nature.

16 Apr 2009

Move over, Y chromosome - it's time X got some attention

In the first evolutionary study of the chromosome associated with being female, University of California, Berkeley, biologist Doris Bachtrog and her colleagues show that the history of the X chromosome is every bit as interesting as the much-studied, male-determining Y chromosome, and offers important clues to the origins and benefits of sexual reproduction.

16 Apr 2009

Survival mode that protects cells when oxygen is low also slows aging

A biochemical pathway that helps keep cells alive when oxygen is low also plays a role in longevity and resistance against some diseases of old age, according to a report to be published April 16 in the journal Science.

16 Apr 2009

Disruption of copper regulation key to prion diseases

An investigation of a rare, inherited form of Creutzfeldt-Jakob disease suggests that disrupted regulation of copper ions in the brain may be a key factor in this and other prion diseases.

16 Apr 2009

Star Scientific reports on patent application for Zero-Nitrosamine tobacco curing process

Star Scientific and its wholly-owned subsidiary, Rock Creek Pharmaceuticals ("Rock Creek"), have reported on their continuing efforts to lessen the harm linked with tobacco use.

16 Apr 2009

Somanetics announces new FDA 510(K) clearance

Somanetics Corporation has announced a new 510(k) clearance from the U.S. Food and Drug Administration (FDA) to expand the labeling for its INVOS(R) Cerebral/Somatic Oximeter.

16 Apr 2009

Singapore scientists synthesize gold to shed light on cells' inner workings

Highly fluorescent gold nanoclusters for sub-cellular imaging have been synthesized by researchers at the Institute of Bioengineering and Nanotechnology (IBN), one of the research institutes of Singapore's A*STAR (Agency for Science, Technology and Research).

16 Apr 2009