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Study observes virologic rebound in 20% of COVID-19 patients treated with nirmatrelvir-ritonavir

An observational study of patients being treated for acute COVID-19 in a multicenter health care system observed virologic rebound in about 20 percent of patients treated with nirmatrelvir-ritonavir (N-R) versus about 2 percent of those who did not receive treatment. The findings are published in Annals of Internal Medicine.

13 Nov 2023

Study shows environment's pivotal role in healthy aging and disease prevention

Study explores new geroscience tools for studying the impact of environmental factors on aging, aiming to delay age-related diseases and disabilities. It highlights how non-genetic factors, like environmental toxins and socio-economic conditions, significantly influence aging and health outcomes.

13 Nov 2023

New physical mechanism uncovered for breast cancer invasion

The majority of breast cancers start in the lining of a breast milk duct and, if they remain there, are very treatable.

13 Nov 2023

Multi-faceted implementation strategy significantly lowers blood pressure in low-income patients

Uncontrolled hypertension, the leading preventable risk factor for cardiovascular disease and premature deaths worldwide, disproportionately affects low-income populations.

13 Nov 2023

Rat study suggests hemodialysis plus ketogenic diet could enhance cancer treatment

The study in Scientific Reports investigates the potential of hemodialysis (HD) to sustain elevated blood ketone levels in rats on a ketogenic diet, exploring its use as an adjunct in cancer treatment. Results show that HD maintains ketone levels while reducing glucose and insulin, suggesting a possible enhancement in cancer treatment efficacy.

13 Nov 2023

Novel assay may improve detection and treatment of acute myeloid leukemia

A novel assay that detects a unique molecular marker in patients with acute myeloid leukemia (AML) may revolutionize the way this disease is detected and treated according to a new report in The Journal of Molecular Diagnostics published by Elsevier.

13 Nov 2023

Study reveals coadministered COVID-19 and flu vaccines effective, especially in seniors

The study in JAMA Network Open evaluates the effectiveness of simultaneously administering the Pfizer-BioNTech BNT162b2 BA.4/5 COVID-19 vaccine and seasonal influenza vaccines versus separate administration. Results suggest similar or slightly increased COVID-19 outcomes and lower influenza-related outcomes with coadministration, particularly in those aged 65 and above.

13 Nov 2023

Automated referrals to pharmacy services dramatically increase appropriate statin prescription rates

The odds of prescribing the appropriate dose of statins - a medicine used to lower "bad" cholesterol levels - increased sixfold when automated referrals were made to pharmacy services, instead of relying on traditional prescribing methods, according to researchers at the Perelman School of Medicine at the University of Pennsylvania.

13 Nov 2023

One in five individuals taking nirmatrelvir-ritonavir therapy found to experience rebound COVID

A new study by investigators from Mass General Brigham found that one in five individuals taking Nirmatrelvir-ritonavir therapy, commonly known as Paxlovid, to treat severe symptoms of COVID-19, experienced a positive test result and shedding of live and potentially contagious virus following an initial recovery and negative test - a phenomenon known as virologic rebound.

13 Nov 2023

Hospital-acquired COVID-19 mortality drops in Omicron era post-vaccination, reveals Swedish study

In a study published in JAMA Network Open, researchers found that hospital-acquired SARS-CoV-2 infections in Stockholm led to increased 30-day mortality in the pre-vaccination period but showed significantly lower mortality during the Omicron wave post-vaccination. The study underscores the importance of vaccination in reducing mortality risks from nosocomial SARS-CoV-2 infections.

13 Nov 2023

Brain-inspired computing system achieves high accuracy in handwritten digit recognition

An experimental computing system physically modeled after the biological brain "learned" to identify handwritten numbers with an overall accuracy of 93.4%. The key innovation in the experiment was a new training algorithm that gave the system continuous information about its success at the task in real time while it learned.

13 Nov 2023

Non-invasive device detects Alzheimer's and Parkinson's biomarkers with high accuracy

An international team of researchers has developed a handheld, non-invasive device that can detect biomarkers for Alzheimer's and Parkinson's Diseases.

13 Nov 2023

Study unravels the molecular mechanisms underlying influenza B virus pathogenicity

Announcing a new article publication for Zoonoses journal. Influenza B virus is a significant respiratory pathogen responsible for seasonal influenza.

13 Nov 2023

AI-powered method could revolutionize cancer treatment by interpreting tumor tissue data

Researchers at Karolinska Institutet and SciLifeLab in Sweden have combined artificial intelligence (AI) techniques used in satellite imaging and community ecology to interpret large amounts of data from tumor tissue.

13 Nov 2023

Study reveals no neuroinflammation in long COVID patients with neuropsychiatric symptoms

In a JAMA Network Open study, researchers found no evidence of neuroinflammation or blood-brain barrier dysfunction in cerebrospinal fluid markers of individuals with post-COVID-19 condition and neuropsychiatric symptoms compared to controls. The study, which assessed cytokines, chemokines, and neuroinflammation markers, suggests that persistent central nervous system immune activation may not be the primary driver of neurological long COVID symptoms.

13 Nov 2023

Study reveals underuse of antiviral medications in young children with influenza

Despite national medical guidelines supporting the use of antiviral medications in young children diagnosed with influenza, a new study reports an underuse of the treatment.

13 Nov 2023

Young people begin to use nicotine through vaping rather than through cigarettes

Young adults are now more likely to vape than to use traditional cigarettes. After years of public health success in decreasing the numbers of people using cigarettes, researchers are seeing striking increases in the numbers of young people who use e-cigarettes regularly – so much so that, for the first time, there are more young people who begin to use nicotine through vaping rather than through cigarettes.

13 Nov 2023

"Christchurch mutation" can block detrimental effects of Alzheimer’s risk factor

Researchers at Gladstone Institutes have discovered that a rare genetic variant known as the "Christchurch mutation" can block detrimental effects of apolipoprotein E4, the best-established risk factor for the most common form of Alzheimer's disease.

13 Nov 2023

Study uncovers how COVID-19 pandemic created new social disparities and affected existing inequalities

An article by Stockholm University researchers was recently published in the Proceedings of the National Academy of Sciences (PNAS).

13 Nov 2023

Optimal hydration post-exercise: Study compares sodium and carbohydrate levels in sports drinks for effective rehydration

In this study, researchers compared the effectiveness of sports drinks with varying carbohydrate and sodium levels for rehydrating athletes post-exercise, finding that drinks with higher sodium and lower carbohydrate content were more effective for rapid and complete rehydration. The study highlighted the importance of beverage composition in athlete recovery and hydration strategies.

13 Nov 2023

Medical News

Study observes virologic rebound in 20% of COVID-19 patients treated with nirmatrelvir-ritonavir

Study shows environment's pivotal role in healthy aging and disease prevention

New physical mechanism uncovered for breast cancer invasion

Multi-faceted implementation strategy significantly lowers blood pressure in low-income patients

Rat study suggests hemodialysis plus ketogenic diet could enhance cancer treatment

Novel assay may improve detection and treatment of acute myeloid leukemia

Study reveals coadministered COVID-19 and flu vaccines effective, especially in seniors

Automated referrals to pharmacy services dramatically increase appropriate statin prescription rates

One in five individuals taking nirmatrelvir-ritonavir therapy found to experience rebound COVID

Hospital-acquired COVID-19 mortality drops in Omicron era post-vaccination, reveals Swedish study

Brain-inspired computing system achieves high accuracy in handwritten digit recognition

Non-invasive device detects Alzheimer's and Parkinson's biomarkers with high accuracy

Study unravels the molecular mechanisms underlying influenza B virus pathogenicity

AI-powered method could revolutionize cancer treatment by interpreting tumor tissue data

Study reveals no neuroinflammation in long COVID patients with neuropsychiatric symptoms

Study reveals underuse of antiviral medications in young children with influenza

Young people begin to use nicotine through vaping rather than through cigarettes

"Christchurch mutation" can block detrimental effects of Alzheimer’s risk factor

Study uncovers how COVID-19 pandemic created new social disparities and affected existing inequalities

Optimal hydration post-exercise: Study compares sodium and carbohydrate levels in sports drinks for effective rehydration

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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