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Missing link between fructose, insulin resistance found

A new study in mice sheds light on the insulin resistance that can come from diets loaded with high-fructose corn syrup, a sweetener found in most sodas and many other processed foods.

3 Mar 2009

Regular moderate alcohol intake associated with greater bone mineral density

Researchers at the Jean Mayer USDA Human Nutrition Research Center on Aging (USDA HNRCA) at Tufts University found associations were strongest for beer and wine and, importantly, BMD was significantly lower in men drinking more than two servings of liquor per day.

3 Mar 2009

Trial looks at telmisartan in treating non-alcoholic steatohepatitis

Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are well-recognized causes of progressive liver disease leading to cirrhosis and hepatocellular carcinoma.

3 Mar 2009

Is esomeprazole the best choice for reflux esophagitis patients?

In patients with gastroesophageal reflux disease (GERD), esomeprazole, has demonstrated pharmacological and clinical benefits beyond those seen with the other proton pump inhibitors (PPIs).

3 Mar 2009

Insecticidal toxin useless without 'friendly' bacteria accomplices

The toxin produced by the bacterium Bacillus thuringiensis (Bt) is a popular insecticide used to control pest moths and butterflies, and in some GM pest-proof crops.

3 Mar 2009

Low energy density diet offsets influence of obesity gene

Children who carry a gene strongly associated with obesity could offset its effect by eating a low energy density diet, according to new research from UCL (University College London) and the University of Bristol published today in PLoS ONE.

3 Mar 2009

Inactivity of proteins behind longer shelf life when freezing

Frozen biological material, for example food, can be kept for a long time without perishing.

3 Mar 2009

Multiple childhood maltreatments lead to greater adolescent binge drinking

Researchers from Boston University found that multiple types of child maltreatment are robust risk factors for underage binge drinking based on a national multi-year study that explored the influence of social environment on the health of adolescents.

3 Mar 2009

Personality factors can influence the development of alcohol dependence

Researchers examined a group of AD individuals with the inactive form of aldehyde dehydrogenase-2 (ALDH2) - persons who would normally have a low incidence of alcoholism because the inactive form of ALDH2 causes flushing, nausea, and headaches. Results indicate that a strong need for novelty and little need for avoiding harm appear to increase the risk of AD.

3 Mar 2009

FDA warning letter to Genzyme related to Allston manufacturing facility

BioMarin Pharmaceutical Inc. (NASDAQ:BMRN) announced today that the FDA warning letter issued to Genzyme addressing deficiencies related to Genzyme's Allston Landing manufacturing facility during an inspection performed in September and October 2008 has no foreseeable impact on the supply of Aldurazyme.

3 Mar 2009

A tipple a day may increase pancreatic cancer risk

Men and women who consume two or more alcoholic drinks a day could increase their risk of developing pancreatic cancer, according to a study published in Cancer Epidemiology, Biomarkers and Prevention , a journal of the American Association for Cancer Research.

3 Mar 2009

FDA provides positive review of InNexus' lead preclinical drug candidate

InNexus Biotechnology Inc. has announced the United States Food & Drug Administration (FDA) has completed its comprehensive review of the development plans for InNexus' lead preclinical candidate, DXL625 (CD20) for the prospective treatment of Non-Hodgkin's Lymphoma (NHL) and/or Chronic Lymphocytic Leukemia (CLL).

3 Mar 2009

FDA clears Cellectar's IND application for lead drug candidate

Cellectar, Inc. has announced that the U.S. Food and Drug Administration (FDA) has cleared the Company's Investigational New Drug (IND) application for its (131)I-CLR1404 drug candidate for testing in patients with advanced solid malignancies.

3 Mar 2009

High-density of fast food outlets affects residents' weight and waist size

In a research article published recently by the American Journal of Epidemiology , Oregon Research Institute (ORI) scientist Fuzhong Li, Ph.D., and colleagues show that a high-density of fast food outlets was associated with an increase of 3 pounds in weight and .8 inches in waist circumference among neighborhood residents who frequently ate at those restaurants.

3 Mar 2009

Research looks at protective effects of acupuncture against NSAID-induced ulceration in a rat model

Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used as anti-inflammatory and analgesic agents.

3 Mar 2009

Drugs that act on 'fasting signal' may curb insulin resistance in obese

A report in the March issue of Cell Metabolism , a Cell Press publication, has found that a signal known to play a role during fasting also switches on early in the fat tissue of obese mice as they progress toward type 2 diabetes.

3 Mar 2009

Colonoscopy and virtual colonoscopy, either way get screened!

Today, patients have a wide selection of colorectal cancer screening exams from which to choose, unlike with other types of cancers.

3 Mar 2009

Certain combined medications after heart attack may increase risk of death

Following an acute coronary syndrome such as a heart attack or unstable angina, patients who receive a medication to reduce the risk of gastrointestinal bleeding that may be associated with the use of the antiplatelet drug clopidogrel and aspirin have an increased risk of subsequent hospitalization for acute coronary syndrome or death, according to a study in the March 4 issue of JAMA, the Journal of the American Medical Association.

3 Mar 2009

Boston Scientific launches Taxus Liberte drug-eluting stent in Japan

Boston Scientific Corporation has announced the launch of its TAXUS Liberte Paclitaxel-Eluting Coronary Stent System in Japan.

3 Mar 2009

Bionovo announces publication of positive trial results for Menerba

Bionovo, Inc. has announced the online publication of a peer-reviewed article in the journal, Menopause, reporting Menerba (formerly MF101) is well tolerated, safe and effective for the treatment of vasomotor symptoms (hot flashes and night sweats) associated with menopause.

3 Mar 2009