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Gene therapy used to alleviate sickle cell disease pathology

Using a harmless virus to insert a corrective gene into mouse blood cells, scientists at St. Jude Children's Research Hospital have alleviated sickle cell disease pathology.

3 Dec 2008

Discovery of gene variants that impact the placebo effect

It is a well-known fact in drug trials that individuals can respond just as well to placebos, sugar pills, as to the active drug.

3 Dec 2008

Brains of low-income children function differently from brains of high-income kids

University of California, Berkeley, researchers have shown for the first time that the brains of low-income children function differently from the brains of high-income kids.

3 Dec 2008

New insights into cellular senescence

Scientists have identified a molecular cause behind the ravages of old age and in doing so have also shown how a natural process for fighting cancer in younger persons can actually promote cancer in older individuals.

3 Dec 2008

Researchers study newborns' umbilical cord blood to better understand fetal health risks from smoking mothers

Despite the well-known dangers of first- and secondhand smoke, an estimated ten percent of pregnant women in the U.S. are smokers.

3 Dec 2008

Broccoli compound, indole-3-carbinol targets key enzyme in late-stage cancer

An anti-cancer compound found in broccoli and cabbage works by lowering the activity of an enzyme associated with rapidly advancing breast cancer, according to a University of California, Berkeley, study appearing this week in the online early edition of the journal Proceedings of the National Academy of Sciences.

3 Dec 2008

More alkaline diet strengthens skeletal health

Diets that are high in protein and cereal grains produce an excess of acid in the body which may increase calcium excretion and weaken bones, according to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

3 Dec 2008

Men who survive childhood leukemia have lower bone mineral density

Men who survived childhood leukemia treatment into adulthood were more likely to have low bone mineral density than other adults their age, putting them at risk of osteoporosis and bone fractures, according to a new study.

3 Dec 2008

Researchers develop human embryonic stem cell-based system for modeling ALS

Long thought of as mere bystanders, astrocytes are crucial for the survival and well-being of motor neurons, which control voluntary muscle movements.

3 Dec 2008

Alpha-catenin protein provokes healthy cell bonding

In human relationships, a certain "spark" often governs whether we prefer one person more than another, and critical first impressions can occur within seconds. A team lead by Johns Hopkins researchers has found that cell-to-cell "friendships" operate in much the same way and that dysfunctional bonding is linked to the spread of cancer.

3 Dec 2008

Study to look at nutrition, ageing and health in Bangladeshi women

The Bangladeshi population is one of the fastest growing ethnic groups within the UK, and are amongst the most socially disadvantaged. A grant of over £500,000 hopes to reduce existing health inequalities and promote healthy, active ageing among Bangladeshi women.

3 Dec 2008

New technique to watch for eye disease

The monitoring and treatment of eye diseases that may cause blindness has taken a big leap forward, thanks to a new imaging technique that takes high quality colour photographs of the whole retina.

3 Dec 2008

Interferon needed for cells to 'remember' how to defeat a virus

Scientists at UT Southwestern Medical Center have determined that the immune-system protein interferon plays a key role in "teaching" the immune system how to fight off repeated infections of the same virus.

3 Dec 2008

New evidence shows that the heart beats to its own drummer

They've uncovered some of the molecular circuitry within the cardiovascular system itself that controls the daily rise and fall of blood pressure and heart rate. The findings might also explain why commonly used diabetes drugs come with cardiovascular benefits, according to the researchers.

3 Dec 2008

New vaccine theory aimed at ticks and mosquitoes to prevent disease transmission

Most successful vaccines and drugs rely on protecting humans or animals by blocking certain bacteria from growing in their systems.

3 Dec 2008

Use of rapid response team in hospital not linked with reduction in cardio arrests or deaths

Although there is an effort to implement rapid response teams in hospitals throughout the country, new research suggests that they do not result in a reduced rate of cardiopulmonary arrests or deaths, according to a study in the December 3 issue of JAMA.

3 Dec 2008

Two alcoholic drinks per day not linked with higher risk of atrial fibrillation for women

Women who have up to two alcoholic drinks per day do not appear to be at increased risk of atrial fibrillation (irregular heart beat), but drinking more than that amount is associated with a higher risk, according to a study in the December 3 issue of JAMA, the Journal of the American Medical Association.

3 Dec 2008