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Blood transfusions associated with infection

A study of almost 25,000 coronary artery bypass graft (CABG) patients has shown that receiving blood from another person is associated with a two-fold increase in post-operative infection rates. The research, published in the open access journal BMC Medicine, also found considerable hospital variation in transfusion practices.

30 Jul 2009

Machine designed to reduce infections and cut back on expensive "disposables"

Johns Hopkins experts in applied physics, computer engineering, infectious diseases, emergency medicine, microbiology, pathology and surgery have unveiled a 7-foot-tall, $10,000 shower-cubicle-shaped device that automatically sanitizes in 30 minutes all sorts of hard-to-clean equipment in the highly trafficked hospital emergency department.

30 Jul 2009

Colchicine approved for acute gout, Mediterranean fever

The U.S. Food and Drug Administration has approved Colcrys to treat acute flairs in patients with gout, a recurrent and painful form of arthritis, and patients with familial Mediterranean fever (FMF), an inherited inflammatory disorder. The medication's active ingredient is colchicine, a complex compound derived from the dried seeds of a plant known as the autumn crocus or meadow saffron (Colchicum autumnale).

30 Jul 2009

Americans spent $33.9 billion out-of-pocket on complementary and alternative medicine

Americans spent $33.9 billion out-of-pocket on complementary and alternative medicine (CAM) over the previous 12 months, according to a 2007 government survey.

30 Jul 2009

Short-term complications after bariatric surgery for extreme obesity low

Short-term complications and death rates were low following bariatric surgery to limit the amount of food that can enter the stomach, decrease absorption of food or both, according to the Longitudinal Assessment of Bariatric Surgery (LABS-1). The study was funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health. Results are reported in the July 30 issue of the New England Journal of Medicine.

30 Jul 2009

UV radiation from sunlight may trigger certain autoimmune diseases in women

Ultraviolet (UV) radiation from sunlight may be associated with the development of certain autoimmune diseases, particularly in women, according to a study by researchers at the National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health.

30 Jul 2009

Nanoparticles show potential as part of new therapy for advanced ovarian cancer

Nanoparticle delivery of diphtheria toxin-encoding DNA selectively expressed in ovarian cancer cells reduced the burden of ovarian tumors in mice, and researchers expect this therapy could be tested in humans within 18 to 24 months, according to a report in Cancer Research, a journal of the American Association for Cancer Research.

30 Jul 2009

Higher drug doses needed to defeat tuberculosis in overweight and obese

The typical dose of a medication considered pivotal in treating tuberculosis effectively is much too low to account for modern-day physiques, UT Southwestern Medical Center researchers said.

30 Jul 2009

Depression missed and misidentified

A meta-analysis of more than 50,000 patients has shown that general practitioners (GPs) have great difficulty separating those with and without depression, with substantial numbers of missed and misidentified.

30 Jul 2009

Hospital dramatically increases transplant donations by integrating bereavement and donor services

A UK hospital that combined its bereavement and donation services saw a forty-fold increase in tissue donations, such as corneas, in just five years, according to research in the August issue of Anaesthesia.

30 Jul 2009

Epigenetic signature changes in low oxygen levels may contribute to prostate cancer development

UCD Conway researchers have characterised epigenetic signature changes in prostate cells under conditions of low oxygen levels that may lead to tumour development.

30 Jul 2009

Covance enters strategic genomic services agreement with Merck

Covance has announced it has entered into a definitive agreement with Merck & Co., Inc. relating to the supply of genomic analysis services.

30 Jul 2009

Protein level may predict severe osteoarthritis

Osteoarthritis (OA), the most common joint disorder throughout the world and a leading cause of disability, is characterized by pain, impaired joint mobility, reduction of muscular strength and loss of joint function. Unlike most other common diseases, little is known about its origins, and factors predicting a severe disease course have not been identified.

30 Jul 2009

Immune responses to flu vaccine are diminished in lupus patients

Patients with the autoimmune disease systemic lupus erythematosus (SLE) have an increased risk of infection, due to both disturbances in their immune responses and treatment with immunosuppressive drugs.

30 Jul 2009

"Free-rider" penalty for employers draws ire from advocates, yawns from business

A "free-rider" penalty being considered by members of the Senate Finance Committee isn't getting a free ride from advocates for low-wage workers and labor unions.

30 Jul 2009

Jubilant Democrats move ahead, but still face many obstacles on reform

After weeks of painstaking talks, Democrats celebrated breakthroughs on health care overhaul on both sides of the Capitol. Yet many lawmakers and health care experts said that yesterday's events marked only one step on the very bumpy road to a final deal that President Barack Obama might sign into law.

30 Jul 2009

Energy and commerce Blue Dogs make deal with House leaders, Liberal members rebel

Roll Call: "House leaders who have struggled for weeks to bring fiscally conservative Blue Dog Democrats on board announced a deal paving the way to get the bill through the Energy and Commerce Committee, but not to the floor, before the August break. But the agreement ran into a firestorm of resistance from liberal Members, forcing Chairman Henry Waxman (D-Calif.) to postpone plans for a markup Wednesday afternoon.

30 Jul 2009

Myths of the public health plan

It's a critical week in Congress on the health care reform front, and members are ramping up the rhetoric for one of the sticking points -- a government-run health insurance plan that would "compete" with private insurers.

30 Jul 2009

Senate Committee's reform bill could cover 95 percent of uninsured

"Senate Finance Committee Chairman Max Baucus, D-Mont., said Wednesday that a preliminary Congressional Budget Office score of his panel's draft health care overhaul package would cost under $900 billion over the next decade and provide health coverage to 95 percent of uninsured Americans," according to Kaiser Health News.

30 Jul 2009

Coming to a doctor's office near you: photo ID check

Elena Castro was finishing the paperwork to buy her first home when the bank called to warn her of a problem-- nearly $10,000 in unpaid hospital bills on her credit report. The charges were for several ear, nose and throat procedures done at hospitals in her region.

30 Jul 2009