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New method for implanting aortic heart valves

An innovative approach for implanting a new aortic heart valve without open-heart surgery is being offered to patients at NewYork-Presbyterian Hospital/Columbia University Medical Center.

7 Jan 2009

Health-care providers and patients differ on views of knee replacement

Total knee replacement (TKR) is a common treatment for osteoarthritis, a disease affecting more than 20 million Americans.

7 Jan 2009

GSK completes tender offer for shares of Genelabs Technologies

GlaxoSmithKline plc has announced the successful completion of the tender offer by its wholly-owned subsidiary Gemstone Acquisition Corporation for shares of common stock of Genelabs Technologies, Inc.

7 Jan 2009

Gene marker may improve odds of stem cell therapies for disease

A single tumor-suppressor gene may provide a unique marker for senescence in Mesenchymal stem cells (MSCs) in vitro, while also playing a role in moving MSCs into senescence, researchers at the Human Health Foundation and the Sbarro Institute for Cancer Research and Molecular Medicine report.

7 Jan 2009

Gene mutations found to predict acute lymphoblastic leukemia relapse

Scientists have identified mutations in a gene that predict a high likelihood of relapse in children with acute lymphoblastic leukemia (ALL).

7 Jan 2009

Fighting childhood obesity should be a family affair

Fighting childhood obesity, which is a serious concern in our country, should be looked upon as a family affair.

7 Jan 2009

Lilly receives complete response letter for Olanzapine LAI for treatment of schizophrenia

Eli Lilly and Company has announced that it received a complete response letter from the U.S. Food and Drug Administration (FDA) for olanzapine long-acting injection (LAI) for acute and maintenance treatment of schizophrenia in adults.

7 Jan 2009

Widespread antiviral drug use can accelerate the evolution of drug resistance in viruses

Influenza's ability to resist the effects of cheap and popular antiviral agents in Asia and Russia should serve as a cautionary tale about U.S. plans to use the antiviral Tamiflu in the event of widespread avian flu infection in humans, scientists say.

7 Jan 2009

Lasers show potential to 'zap' amyloid proteins

Researchers have found that a technique used to visualize amyloid fibers in the laboratory might have the potential to destroy them in the clinic.

7 Jan 2009

Drive toward containing health care costs could have consequences for health care delivery

The drive toward containing health care costs could have the unintended consequence of reducing physician productivity, impairing quality and perhaps even increasing costs, two Beth Israel Deaconess Medical Center physicians suggest in a New England Journal of Medicine "Perspective."

7 Jan 2009

Discovery of more efficient way to create induced Pluripotent Stem (iPS) cells

A Boston University School of Medicine-led research team has discovered a more efficient way to create induced Pluripotent Stem (iPS) cells, derived from mouse fibroblasts, by using a single virus vector instead of multiple viruses in the reprogramming process.

7 Jan 2009

Codexis announces licensing agreement with Teva Pharmaceutical Industries

Codexis, Inc. today announced a licensing agreement with Teva Pharmaceutical Industries Ltd., to produce an important publicly-undisclosed generic product, using a proprietary Codexis biocatalyst.

7 Jan 2009

Bird flu becoming more resistant to antivirals

A new University of Colorado at Boulder study shows the resistance of the avian flu virus to a major class of antiviral drugs is increasing through positive evolutionary selection, with researchers documenting the trend in more than 30 percent of the samples tested.

7 Jan 2009

New Benzothiazepine test will catch sports cheats

Avoiding detection just got harder for drug cheats who try to use a particular range of untested, but potentially enhancing, compounds.

7 Jan 2009

Adolescents with arthritis need more information when transitioning to adult care

Helping adolescents with arthritis develop the skills and secure resources to assure that their health care needs are met as they transition to adulthood is an important issue in the U.S. In general, the frequency of which young people with special health care needs receive transition services is low and, to date, no studies have examined this frequency.

7 Jan 2009

Lack of human calmodulin-like protein can be indicative of oral cancer

Human calmodulin-like protein (CLP) is found in many cell types including breast, thyroid, prostate, kidney, and skin.

7 Jan 2009

A new state-of-the-art approach to brain and spine surgery

A medical revolution emerges when technology blends with smart care.

7 Jan 2009

Liquidia Technologies to collaborate with Abbott on siRNA therapeutics

Liquidia Technologies, Inc. announced today that it has entered into a collaboration and license agreement with Abbott to develop PRINT nanoparticles for the delivery of siRNA-based therapeutics. Liquidia's PRINT technology offers the ability to fabricate nanoparticles of precisely defined size, shape, surface chemistry, and composition, which offers the potential to develop safer and more effective therapies.

7 Jan 2009

Control of blood vessels a possible weapon against obesity

Mice exposed to low temperatures develop more blood vessels in their adipose tissue and metabolise body fat more quickly, according to a new study from Karolinska Institutet. Scientists now hope to learn how to control blood vessel development in humans in order to combat obesity and diabetes.

7 Jan 2009