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Phase 2 trial of treatment of C-difficile-associated diarrhea shows promise

Medarex, Inc. and The Massachusetts Biologic Laboratories (MBL) of the University of Massachusetts Medical School (UMMS) today announced that a Phase 2 trial of an anti- C. difficile antibody combination treatment in patients with C.

4 Nov 2008

Parents comfortable with alcohol screening in pediatricians' offices

Parents are surprisingly receptive to being screened for alcohol problems during a visit to their child's pediatrician, including those who have alcohol problems.

4 Nov 2008

Parasites that live inside cells use loophole to thwart immune system

St. Jude Children's Research Hospital scientists have discovered a mechanism by which intracellular pathogens can shut down one of the body's key chemical weapons against them: nitric oxide.

4 Nov 2008

Biologists identify genes that prevent changes in physical traits due to environmental changes

New York University biologists have identified genes that prevent physical traits from being affected by environmental changes.

4 Nov 2008

Novel leukemia therapy shows promise for high-risk patients

Researchers at the Moores Cancer Center at the University of California, San Diego (UCSD) are conducting clinical trials of a novel therapy aimed at revving up the immune system to combat a particularly difficult-to-treat form of leukemia.

4 Nov 2008

Two different approaches used to correct clubfoot both bring positive outcomes for most children

Two non-surgical treatments most commonly used to correct the condition known as clubfoot have similarly high levels of success, according to a new study published in the November 2008 issue of The Journal of Bone and Joint Surgery.

4 Nov 2008

Discovery of biomarkers for esophageal cancer before it develops

Rhode Island Hospital researchers have identified genetic proteins, also known as biomarkers, capable of distinguishing changes at the microscopic level that can signal a precancerous condition in the esophagus.

4 Nov 2008

New model helps estimate radiation skin doses during CT-guided interventional procedures

A new model that would allow interventional radiologists (radiologists who specialize in fine needle aspiration, fine needle biopsy and radiofrequency ablation) to better estimate patient radiation skin doses during CT guided interventional procedures has been developed according to a study performed at the Agios Savvas and Konstantopoulio Hospitals in Athens, Greece.

4 Nov 2008

Just one mutated SMAD4 allele is enough to cause cancer

Tumour suppressor genes do not necessarily require both alleles to be knocked out before disease phenotypes are expressed.

4 Nov 2008

Two new studies defend homeopathy

Two new studies conclude that a review which claimed that homeopathy is just a placebo, published in The Lancet, was seriously flawed.

4 Nov 2008

MRI reveals relationship between depression and pain

The brains of individuals with major depressive disorder appear to react more strongly when anticipating pain and also display altered functioning of the neural network that modifies pain sensitivity, according to a report in the November issue of Archives of General Psychiatry , one of the JAMA/Archives journals.

4 Nov 2008

Pre-treatment MRI eliminates unnecessary surgery for children with suspected musculosketal infections

Pre-treatment MRI can eliminate unnecessary diagnostic or surgical procedures for children with suspected musculoskeletal infections (septic arthritis and osteomyelitis) according to a study performed at Vanderbilt Children's Hospital in Nashville, TN.

4 Nov 2008

Potential therapeutic target for acute leukemia types

Research using a new mouse model has led to the identification of a potential therapeutic target for a type of leukemia commonly associated with an unfavorable prognosis.

4 Nov 2008

The two-pacemaker system

Two pacemakers in the brain work together in harmony to ensure that breathing occurs in a regular rhythm, according to new research from MIT scientists.

4 Nov 2008

Minor shift in vaccine schedule has potential to reduce infant illness, death

A new study by researchers at Wake Forest University School of Medicine and Vanderbilt University suggests that protecting infants from a common, highly contagious and even deadly disease may be as easy as administering a routine vaccine two weeks earlier than it is typically given.

4 Nov 2008

Study looks at children and teens physically victimized by peers

Mentoring youths, counseling parents can reduce youth violence, researchers say

4 Nov 2008

Analysis of Multidetector CT for detection of airway stent complications

Multidetector CT (MDCT) scans are highly accurate in detecting airway stent complications according to a recent study performed at Beth Israel Deaconess Medical Center and Harvard Medical School in Boston, MA.

4 Nov 2008

Living with smokers may be associated with inadequate access to food

Children and adults living with adult smokers appear less likely to have daily access to enough healthy food compared with those living with non-smoking adults, according to a report in the November issue of Archives of Pediatrics & Adolescent Medicine.

4 Nov 2008

Liver transplant recipients face increased risks of developing cancer

A new Canadian study comparing cancer rates of liver transplant patients to those of the general population has found that transplant recipients face increased risks of developing cancer, especially non-Hodgkin's lymphoma and colorectal cancer.

4 Nov 2008

ADHD appears to affect movement in boys more than it does in girls

Attention deficit hyperactivity disorder (ADHD) appears to affect movement in boys more than it does in girls, according to a study published in the November 4, 2008, issue of Neurology, the medical journal of the American Academy of Neurology.

4 Nov 2008