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Lower blood levels of vitamin D linked to increased heart problems

Individuals with lower blood levels of vitamin D appear to have an increased risk of death overall and from cardiovascular causes, according to a report in the June 23 issue of Archives of Internal Medicine.

23 Jun 2008

Study: Outreach and internal navigation program on breast cancer diagnosis in an urban cancer center with a large African-American population

A new study indicates that community education outreach and internal navigation programs lead to a significant shift in stage at diagnosis of breast cancer among African American women, with a doubling in the proportion of cases caught at the earliest stage and a nearly reciprocal drop in the proportion of cancers at most advanced stage.

23 Jun 2008

The impact of socioeconomic status on survival after cancer in the United States

Cancer patients with low socioeconomic status (SES) have more advanced cancers at diagnosis, receive less aggressive treatment, and have a higher risk of dying in the five years following cancer diagnosis, according to a new study.

23 Jun 2008

How mothers interact with their babies related to how children behave later on

The way mothers interact with their babies in the first year of life is strongly related to how children behave later on. Both a mother's parenting style and an infant's temperament reliably predict challenging behavior in later childhood, according to Benjamin Lahey and his team from the University of Chicago in the US. Their findings have just been published online in Springer's Journal of Abnormal Child Psychology.

23 Jun 2008

Hedgehog signaling is critical for maintenance of the adult coronary vasculature

A set of promising new anticancer agents could have unforeseen risks in individuals with heart disease, suggests research at Washington University School of Medicine in St. Louis.

23 Jun 2008

New, previously unrecognized source of heart stem cells discovered

Researchers at Children's Hospital Boston are continuing to document the heart's earliest origins. Now, they have pinpointed a new, previously unrecognized group of stem cells that give rise to cardiomyocytes, or heart muscle cells. These stem cells, located in the surface of the heart, or epicardium, advance the hope of being able to regenerate injured heart tissue.

23 Jun 2008

New way to limit gene transfer and expression

Researchers from Northwestern University and Texas A & M University have discovered a new way to limit gene transfer and expression to specific tissues in animals.

23 Jun 2008

Evidence for an increased cancer risk following the use of radioactive Radium-224 in the therapy for Ankylosing Spondylitis

In the course of an epidemiological study, scientists of the Institute of Radiation Biology of the Helmholtz Zentrum München - German Research Center for Environmental Health - have established an unfavourable benefit-risk-ratio for ankylosing spondylitis patients treated with Radium-224 therapy (Rheumatology 2008; 47: 855-59).

23 Jun 2008

Childhood prognosis of heart disease in later life

Heart diseases are one of the major causes of death in the western world. Research is under way in the University of Leicester Engineering Department, in collaboration with The Leicester Royal Infirmary, to analyse the heart rate variability of 10 year- old children, in an attempt to identify heart diseases at an early stage.

23 Jun 2008

Management of hypertension immediately after stroke

A research project at the University of Leicester in conjunction with the University of East Anglia, indicates that early reduction of high blood pressure following stroke is feasible and safe, and both Labetalol & Lisinopril were found to be suitable a medications for this purpose.

23 Jun 2008

Could Gleevec help stroke victims?

For over a decade, the drug called tPA has proven its worth as the most effective emergency treatment for the most common kind of stroke. But its promise is blemished by two facts: tPA can cause dangerous bleeding in the brain, and its brain-saving power fades fast after the third hour of a stroke.

23 Jun 2008

Canopus BioPharma enters phase II clinical trials with CB1400

Canopus BioPharma, Inc. has announced that the South African Medicines Control Council has granted approval for a Phase II study in 30 cancer patients evaluating the protective effect of CB1400 on the gastrointestional tract from radiation-induced mucositis. This new trial is an important step forward in the development of CB1400 as a novel, preventative, anti-mucositis agent.

23 Jun 2008

Alchemia granted first two patents in the "Synthetic Heparin Oligosaccharide" family of patents

Alchemia Ltd. has announced the granting of the first two patents in the "Synthetic Heparin Oligosaccharide" family of patents.

23 Jun 2008

FDA lifts clinical hold on Genta's Tesetaxel

Genta Incorporated announced that the Company has received notification from the U.S. Food and Drug Administration (FDA) that Genta may resume clinical trials with tesetaxel, a leading oral taxane in Genta's oncology product portfolio.

23 Jun 2008

Study shows generics now own 63% of Medicare Part D market

Wolters Kluwer Health, a division of Wolters Kluwer, has released the results of a study that looks at key statistical outcomes of the Medicare Part D (MPD) prescription drug program.

23 Jun 2008

Warning on fecal coliform in flooded areas of Iowa

Flood water samples taken by the U.S. Environmental Protection Agency within the city limits of Des Moines, Cedar Rapids, Hamburg, and Burlington, Iowa, showed numbers of fecal coliform bacteria exceeding the health-based level of concern. The level of concern is 200 colony forming units (cfu) per 100 milliliters (ml).

23 Jun 2008