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Drug combo shows potential for treating extensively drug resistant tuberculosis

A combination of two FDA-approved drugs, already approved for fighting other bacterial infections, shows potential for treating extensively drug resistant tuberculosis (XDR-TB), the most deadly form of the infection.

26 Feb 2009

Zoologists search sea for drugs of the future

No matter how sophisticated modern medicine becomes, common ailments like fungal infections can outrun the best of the world's antibiotics.

26 Feb 2009

Clinical practice guidelines for osteoarthritis of the knee

Osteoarthritis (OA) is known as the "wear and tear" arthritis. It can affect any joint in the body particularly after years of use.

26 Feb 2009

Amyloid plaques may increase the activity of astrocytes

The impact of the amyloid plaques that appear in the brains of patients with Alzheimer's disease may extend beyond the deposits' effects on neurons – the cells that transmit electrochemical signals throughout the nervous system.

26 Feb 2009

Immune system found to be more versatile than previously thought

By studying how mice fight off infection by intestinal worms - a condition that affects more than 1 billion people worldwide - scientists have discovered that the immune system is more versatile than has long been thought.

26 Feb 2009

A second MND gene mutation in one year signifies rapid research progress

A collaborative research project involving Professor Christopher Shaw of the Institute of Psychiatry, King's College London (KCL), Dr Tom Kwiatkowski at Massachusetts General Hospital (MGH) and Professor Robert H Brown at University of Massachusetts, has revealed that mutations in a gene called FUS (fused in sarcoma) cause familial Motor Neuron Disease (also known as Amyotrophic Lateral Sclerosis).

26 Feb 2009

VIA Pharmaceuticals awarded new patent on lead compound VIA-2291

VIA Pharmaceuticals, Inc. has announced the issuance of United States Patent No. 7,495,024 entitled "Phenylalkyl N-Hydroxyureas for Combating Atherosclerotic Plaque", covering the use of VIA's lead compound, VIA-2291, for the treatment of atherosclerosis.

25 Feb 2009

United States files complaint against Forest Labs for allegedly violating the false claims act with Celexa and Lexapro

A Complaint was unsealed today in U.S. District Court in Massachusetts against a New York pharmaceutical company for alleged False Claims Act violations arising from the company's marketing the drugs Celexa and Lexapro for unapproved pediatric use and for paying kickbacks to induce physicians to prescribe the drugs.

25 Feb 2009

Scientists make electrically active motor neurons from iPS cells

Stem cells scientists at UCLA showed for the first time that human induced pluripotent stem (iPS) cells can be differentiated into electrically active motor neurons, a discovery that may aid in studying and treating neurological disorders.

25 Feb 2009

Two compounds show great promise for cerebral palsy

Two compounds developed by Northwestern University chemists have been shown to be effective in pre-clinical trials in protecting against cerebral palsy, a condition caused by neurodegeneration that affects body movement and muscle coordination.

25 Feb 2009

Perinatal anxiety - the hidden disorder

You've probably heard of postpartum depression - a common problem after pregnancy, suffered by about one in seven new mothers.

25 Feb 2009

Stages of sleep have distinct influence on process of learning and memory

Research on the sleeping brain has revealed some fascinating stage-dependent interactions between areas involved in formation and storage of long term memories.

25 Feb 2009

Discovery of gene that modifies severity of cystic fibrosis lung disease

Researchers have discovered a gene that modifies the severity of lung disease in people with the lethal genetic condition, cystic fibrosis, pointing to possible new targets for treatment, according to a new study in Nature.

25 Feb 2009

Eavesdropping on cellular communication

Scientists have discovered the secrets of a sophisticated molecule that plays a role in many aspects of human health from fertility to blood pressure; digestion to mental health.

25 Feb 2009

New statistical model could predict an individual's lifetime risk of stroke

Using genetic information from 569 hospital patients, the researchers showed that their predictive model could estimate an individual's overall risk of cardioembolic stroke -- the most common form of stroke -- with 86 percent accuracy. The findings are reported in the March issue of Stroke.

25 Feb 2009

Physical therapy is effective for management of low-back pain

A new review article published in the Journal of the American Academy of Orthopaedic Surgeons should help convince many patients with low back pain to consider physical therapy as a first line of treatment for their condition, according to the American Physical Therapy Association (APTA).

25 Feb 2009

Parents learn about human papillomavirus vaccine mostly from pharmaceutical advertising

Parents and other caretakers of young women learned about human papillomavirus (HPV) vaccine primarily from advertisements sponsored by the pharmaceutical company that makes the vaccine, a new study from the University of North Carolina at Chapel Hill shows.

25 Feb 2009